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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human Urinary TIM-1/KIM-1/HAVCR Quantikine ELISA Kit
catalog :
DKM100
quantity :
1 Kit (also 1 Pack (6 Plates))
price :
655 USD
citations: 42
Reference
Park S, Yu U, Oh W, Ryu S, Son S, Lee S, et al. Serum and urinary biomarkers of vancomycin-induced acute kidney injury: A prospective, observational analysis. Medicine (Baltimore). 2024;103:e39202 pubmed publisher
Kawakami S, Yasuno T, Kawakami S, Ito A, Fujimi K, Matsuda T, et al. Effects of high-intensity intermittent exercise versus moderate-intensity continuous exercise on renal hemodynamics assessed by ultrasound echo. Physiol Rep. 2024;12:e15925 pubmed publisher
Katz D, Gao Z, Freytag J, Mahendran A, Szugye C, Woodly S, et al. Associations Between Characteristics of Individuals With Fontan Circulation With Blood and Urine Biomarkers of Kidney Injury and Dysfunction. J Am Heart Assoc. 2023;12:e029130 pubmed publisher
Zhang F, Yin J, Liu L, Liu S, Zhang G, Kong Y, et al. IL-17C neutralization protects the kidney against acute injury and chronic injury. EBioMedicine. 2023;92:104607 pubmed publisher
Downes K, Zuppa A, Sharova A, Neely M. Optimizing Vancomycin Therapy in Critically Ill Children: A Population Pharmacokinetics Study to Inform Vancomycin Area under the Curve Estimation Using Novel Biomarkers. Pharmaceutics. 2023;15: pubmed publisher
Farooqui N, Zaidi M, Vaughan L, McKee T, Ahsan E, Pavelko K, et al. Cytokines and Immune Cell Phenotype in Acute Kidney Injury Associated With Immune Checkpoint Inhibitors. Kidney Int Rep. 2023;8:628-641 pubmed publisher
Wu V, Chan C, Chueh J, Chen Y, Lin Y, Chang C, et al. Markers of Kidney Tubular Function Deteriorate While Those of Kidney Tubule Health Improve in Primary Aldosteronism After Targeted Treatments. J Am Heart Assoc. 2023;12:e028146 pubmed publisher
Zhong J, Yang H, Shelton E, Matsusaka T, Clark A, Yermalitsky V, et al. Dicarbonyl-modified lipoproteins contribute to proteinuric kidney injury. JCI Insight. 2022;7: pubmed publisher
Kawakami S, Yasuno T, Kawakami S, Ito A, Fujimi K, Matsuda T, et al. The moderate-intensity continuous exercise maintains renal blood flow and does not impair the renal function. Physiol Rep. 2022;10:e15420 pubmed publisher
Kakkanattu T, Kaur J, Nagesh V, Kundu M, Kamboj K, Kaur P, et al. Serum myo-inositol oxygenase levels at hospital discharge predict progression to chronic kidney disease in community-acquired acute kidney injury. Sci Rep. 2022;12:13225 pubmed publisher
Upadhyay R, Batuman V. Aristolochic acid I induces proximal tubule injury through ROS/HMGB1/mt DNA mediated activation of TLRs. J Cell Mol Med. 2022;26:4277-4291 pubmed publisher
Zeni L, Norden A, Prandi E, Canepa C, Burling K, Simpson K, et al. Exploration of a panel of urine biomarkers of kidney disease in two paediatric cohorts with Type 1 diabetes mellitus of differing duration. Diabetol Metab Syndr. 2022;14:71 pubmed publisher
Bignon Y, Rinaldi A, Nadour Z, Poindessous V, Nemazanyy I, Lenoir O, et al. Cell stress response impairs de novo NAD+ biosynthesis in the kidney. JCI Insight. 2022;7: pubmed publisher
Rumpel J, Spray B, Chock V, Kirkley M, Slagle C, Frymoyer A, et al. Urine Biomarkers for the Assessment of Acute Kidney Injury in Neonates with Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia. J Pediatr. 2022;241:133-140.e3 pubmed publisher
Leśnik P, Woźnica Niesobska E, Janc J, Mierzchała Pasierb M, Łysenko L. Effect of a 3% gelatin solution on urinary KIM-1 levels in patients after thyroidectomy: a preliminary randomized controlled trial. Sci Rep. 2021;11:23617 pubmed publisher
Zhang Y, Xiang C, Gong L, Zhang Y, Zhen J, Hu Z, et al. Kidney injury molecule-1 levels are associated with therapeutic outcomes and renal tubulointerstitial injury severity in idiopathic membranous nephropathy. Exp Ther Med. 2021;22:1434 pubmed publisher
Jacobson M, Wu Y, Liu M, Kannan K, Li A, Robinson M, et al. Organophosphate pesticides and progression of chronic kidney disease among children: A prospective cohort study. Environ Int. 2021;155:106597 pubmed publisher
Østergaard A, Jørgensen A, Bøvling S, Ekeløf N, Mose F, Bech J. Effect of 0.9% NaCl compared to plasma-lyte on biomarkers of kidney injury, sodium excretion and tubular transport proteins in patients undergoing primary uncemented hip replacement - a randomized trial. BMC Nephrol. 2021;22:111 pubmed publisher
Funke B, JACKSON K, Self W, Collins S, Saunders C, Wang L, et al. Effect of balanced crystalloids versus saline on urinary biomarkers of acute kidney injury in critically ill adults. BMC Nephrol. 2021;22:54 pubmed publisher
Latoch E, Konończuk K, Muszyńska Rosłan K, Taranta Janusz K, Wasilewska A, Szymczak E, et al. Urine NGAL and KIM-1-Tubular Injury Biomarkers in Long-Term Survivors of Childhood Solid Tumors: A Cross-Sectional Study. J Clin Med. 2021;10: pubmed publisher
Jacobson M, Wu Y, Liu M, Attinà T, Naidu M, Karthikraj R, et al. Serially assessed bisphenol A and phthalate exposure and association with kidney function in children with chronic kidney disease in the US and Canada: A longitudinal cohort study. PLoS Med. 2020;17:e1003384 pubmed publisher
Wajda J, Dumnicka P, Kolber W, Sporek M, Maziarz B, Ceranowicz P, et al. The Marker of Tubular Injury, Kidney Injury Molecule-1 (KIM-1), in Acute Kidney Injury Complicating Acute Pancreatitis: A Preliminary Study. J Clin Med. 2020;9: pubmed publisher
Branković M, Akkerhuis K, Hoorn E, Van Boven N, van den Berge J, Constantinescu A, et al. Renal tubular damage and worsening renal function in chronic heart failure: Clinical determinants and relation to prognosis (Bio-SHiFT study). Clin Cardiol. 2020;43:630-638 pubmed publisher
Wołyniec W, Kasprowicz K, Giebułtowicz J, Korytowska N, Zorena K, Bartoszewicz M, et al. Changes in Water Soluble Uremic Toxins and Urinary Acute Kidney Injury Biomarkers After 10- and 100-km Runs. Int J Environ Res Public Health. 2019;16: pubmed publisher
Jouffroy R, Lebreton X, Mansencal N, Anglicheau D. Acute kidney injury during an ultra-distance race. PLoS ONE. 2019;14:e0222544 pubmed publisher
Gohda T, Kamei N, Koshida T, Kubota M, Tanaka K, Yamashita Y, et al. Circulating kidney injury molecule-1 as a biomarker of renal parameters in diabetic kidney disease. J Diabetes Investig. 2020;11:435-440 pubmed publisher
Santelli A, Sun I, Eirin A, Abumoawad A, Woollard J, Lerman A, et al. Senescent Kidney Cells in Hypertensive Patients Release Urinary Extracellular Vesicles. J Am Heart Assoc. 2019;8:e012584 pubmed publisher
Huang Y, Tian Y, Likhodii S, Randell E. Baseline urinary KIM-1 concentration in detecting acute kidney injury should be interpreted with patient pre-existing nephropathy. Pract Lab Med. 2019;15:e00118 pubmed publisher
Kostic D, Beozzo G, do Couto S, Kato A, Lima L, Palmeira P, et al. The role of renal biomarkers to predict the need of surgery in congenital urinary tract obstruction in infants. J Pediatr Urol. 2019;15:242.e1-242.e9 pubmed publisher
Jiang Q, Han M, Ma K, Chen G, Wan X, Kilonzo S, et al. Acute kidney injury in acute-on-chronic liver failure is different from in decompensated cirrhosis. World J Gastroenterol. 2018;24:2300-2310 pubmed publisher
Wang J, Chi N, Huang T, Connolly R, Chen L, Chueh S, et al. Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery. Crit Care. 2018;22:108 pubmed publisher
Dayem S, Bohy A, Hamed M, Ahmed S. Follow Up of Value of the Intrarenal Resistivity Indices and Different Renal Biomarkers for Early Identification of Diabetic Nephropathy in Type 1 Diabetic Patients. Open Access Maced J Med Sci. 2017;5:188-192 pubmed publisher
Jin Y, Shao X, Sun B, Miao C, Li Z, Shi Y. Urinary kidney injury molecule?1 as an early diagnostic biomarker of obstructive acute kidney injury and development of a rapid detection method. Mol Med Rep. 2017;15:1229-1235 pubmed publisher
Yiu W, Wong D, Wu H, Li R, Yam I, Chan L, et al. Kallistatin protects against diabetic nephropathy in db/db mice by suppressing AGE-RAGE-induced oxidative stress. Kidney Int. 2016;89:386-98 pubmed
Jongman R, van Klarenbosch J, Molema G, Zijlstra J, de Vries A, van Meurs M. Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass. PLoS ONE. 2015;10:e0136205 pubmed publisher
Xu P, Wei L, Shang W, Tian S, Gu D, Yan T, et al. Urinary kidney injury molecule-1 is related to pathologic involvement in IgA nephropathy with normotension, normal renal function and mild proteinuria. BMC Nephrol. 2014;15:107 pubmed publisher
Peake P, Pianta T, Succar L, Fernando M, Pugh D, McNamara K, et al. A comparison of the ability of levels of urinary biomarker proteins and exosomal mRNA to predict outcomes after renal transplantation. PLoS ONE. 2014;9:e98644 pubmed publisher
Liu W, Luo M, Tan J, Chen W, Huang L, Yang C, et al. Autophagy activation reduces renal tubular injury induced by urinary proteins. Autophagy. 2014;10:243-56 pubmed publisher
Park H, Hwang J, Kang A, Ro H, Kim M, An J, et al. Urinary N-acetyl-?-D glucosaminidase as a surrogate marker for renal function in autosomal dominant polycystic kidney disease: 1 year prospective cohort study. BMC Nephrol. 2012;13:93 pubmed publisher
Conway B, Manoharan D, Manoharan D, Jenks S, Dear J, McLachlan S, et al. Measuring urinary tubular biomarkers in type 2 diabetes does not add prognostic value beyond established risk factors. Kidney Int. 2012;82:812-8 pubmed publisher
de Borst M, Nauta F, Vogt L, Laverman G, Gansevoort R, Navis G. Indomethacin reduces glomerular and tubular damage markers but not renal inflammation in chronic kidney disease patients: a post-hoc analysis. PLoS ONE. 2012;7:e37957 pubmed publisher
Metzger J, Kirsch T, Schiffer E, Ulger P, Mentes E, Brand K, et al. Urinary excretion of twenty peptides forms an early and accurate diagnostic pattern of acute kidney injury. Kidney Int. 2010;78:1252-62 pubmed publisher
product information
master code :
DKM100
SKU :
DKM100
product name :
Human Urinary TIM-1/KIM-1/HAVCR Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (6 Plates))
description :
The Human Urinary TIM-1/KIM-1/HAVCR Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human TIM-1/KIM-1/HAVCR in urine (50 ul).
target :
TIM-1/KIM-1/HAVCR
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human TIM-1
gene symbol :
HAVCR1
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Urine (50 uL)
elisaSensitivity :
0.046 ng/mL
elisaRange :
0.16 - 10 ng/mL
top caption :
Human TIM-1/KIM-1/HAVCR ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human TIM-1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure TIM-1 in urine. It contains NS0-expressed recombinant human TIM-1 and antibodies raised against the recombinant factor. Natural human TIM-1 showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards, indicating that this kit can be used to determine relative levels of natural human TIM-1.
alt names :
CD365, HAVCR1, HAVCR-1, HAVCRT cell immunoglobin domain and mucin domain protein 1, hepatitis A virus cellular receptor 1, Kidney injury molecule 1, KIM1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIM1, TIM-1TIM, TIM1TIMD-1, TIMD1T-cell membrane protein 1
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.