Human Dkk-1 Quantikine ELISA Kit | R&D Systems DKK100B product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human Dkk-1 Quantikine ELISA Kit

catalog :

DKK100B

quantity :

1 Kit

price :

655 USD

citations: 21

Reference
Shi T, Zhang Y, Wang Y, Song X, Wang H, Zhou X, et al. DKK1 Promotes Tumor Immune Evasion and Impedes Anti-PD-1 Treatment by Inducing Immunosuppressive Macrophages in Gastric Cancer. Cancer Immunol Res. 2022;10:1506-1524 pubmed publisher
Papagoras C, Tsiami S, Chrysanthopoulou A, Mitroulis I, Baraliakos X. Serum granulocyte-macrophage colony-stimulating factor (GM-CSF) is increased in patients with active radiographic axial spondyloarthritis and persists despite anti-TNF treatment. Arthritis Res Ther. 2022;24:195 pubmed publisher
Suda T, Yamashita T, Sunagozaka H, Okada H, Nio K, Sakai Y, et al. Dickkopf-1 Promotes Angiogenesis and is a Biomarker for Hepatic Stem Cell-like Hepatocellular Carcinoma. Int J Mol Sci. 2022;23: pubmed publisher
Jung Y, Chae C, Choi G, Shin H, Lim J, Chang H, et al. Cyanidin 3-O-arabinoside suppresses DHT-induced dermal papilla cell senescence by modulating p38-dependent ER-mitochondria contacts. J Biomed Sci. 2022;29:17 pubmed publisher
Kobari L, Auclair M, Piau O, Ferrand N, Zaoui M, Delhommeau F, et al. Circulating cytokines present in multiple myeloma patients inhibit the osteoblastic differentiation of adipose stem cells. Leukemia. 2022;36:540-548 pubmed publisher
Nava Valdivia C, Ponce Guarneros J, Saldaña Cruz A, Corona Sánchez E, Ramirez Villafaña M, Perez Guerrero E, et al. Assessment of Serum sRANKL, sRANKL/OPG Ratio, and Other Bone Turnover Markers with the Estimated 10-Year Risk of Major and Hip Osteoporotic Fractures in Rheumatoid Arthritis: A Cross-Sectional Study. Biomed Res Int. 2021;2021:5567666 pubmed publisher
Galliera E, Massaccesi L, de Benedettis E, Longhi E, De Toma D, Corsi Romanelli M, et al. Longitudinal evaluation of Wnt inhibitors and comparison with others serum osteoimmunological biomarkers in osteolytic bone metastasis. J Leukoc Biol. 2020;108:697-704 pubmed publisher
Diani M, Perego S, Sansoni V, Bertino L, Gomarasca M, Faraldi M, et al. Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic Patients. Int J Mol Sci. 2019;20: pubmed publisher
Mihai S, Codrici E, Popescu I, Enciu A, Rusu E, Zilisteanu D, et al. Inflammation-Related Patterns in the Clinical Staging and Severity Assessment of Chronic Kidney Disease. Dis Markers. 2019;2019:1814304 pubmed publisher
Mambet C, Necula L, Mihai S, Matei L, Bleotu C, Chivu Economescu M, et al. Increased Dkk-1 plasma levels may discriminate disease subtypes in myeloproliferative neoplasms. J Cell Mol Med. 2018;: pubmed publisher
Jadon D, Sengupta R, Nightingale A, Lu H, Dunphy J, Green A, et al. Serum bone-turnover biomarkers are associated with the occurrence of peripheral and axial arthritis in psoriatic disease: a prospective cross-sectional comparative study. Arthritis Res Ther. 2017;19:210 pubmed publisher
Tang X, Lin J, Wang G, Lu J. MicroRNA-433-3p promotes osteoblast differentiation through targeting DKK1 expression. PLoS ONE. 2017;12:e0179860 pubmed publisher
Kim T, Chang J, Park K, Park J, Kim N, Lee J, et al. Effects of exercise training on circulating levels of Dickkpof-1 and secreted frizzled-related protein-1 in breast cancer survivors: A pilot single-blind randomized controlled trial. PLoS ONE. 2017;12:e0171771 pubmed publisher
Niu C, Lin S, Yuan L, Chen L, Yang C, Chung A, et al. Correlation of blood bone turnover biomarkers and Wnt signaling antagonists with AS, DISH, OPLL, and OYL. BMC Musculoskelet Disord. 2017;18:61 pubmed publisher
Lee E, Kim S, Choi B, Kim E, Chung Y, Lee E, et al. Interleukin-32 Gamma Stimulates Bone Formation by Increasing miR-29a in Osteoblastic Cells and Prevents the Development of Osteoporosis. Sci Rep. 2017;7:40240 pubmed publisher
Hartman M, Talar B, Noman M, Gajos Michniewicz A, Chouaib S, Czyz M. Gene expression profiling identifies microphthalmia-associated transcription factor (MITF) and Dickkopf-1 (DKK1) as regulators of microenvironment-driven alterations in melanoma phenotype. PLoS ONE. 2014;9:e95157 pubmed publisher
André T, Meuleman N, Stamatopoulos B, De Bruyn C, Pieters K, Bron D, et al. Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells. PLoS ONE. 2013;8:e59756 pubmed publisher
Scheel C, Eaton E, Li S, Chaffer C, Reinhardt F, Kah K, et al. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell. 2011;145:926-40 pubmed publisher
Gunn W, Krause U, Lee N, Gregory C. Pharmaceutical inhibition of glycogen synthetase kinase-3? reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model. Blood. 2011;117:1641-51 pubmed publisher
Honsawek S, Tanavalee A, Yuktanandana P, Ngarmukos S, Saetan N, Tantavisut S. Dickkopf-1 (Dkk-1) in plasma and synovial fluid is inversely correlated with radiographic severity of knee osteoarthritis patients. BMC Musculoskelet Disord. 2010;11:257 pubmed publisher
Olivares Navarrete R, Hyzy S, Wieland M, Boyan B, Schwartz Z. The roles of Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell maturation state in osteogenesis on microstructured titanium surfaces. Biomaterials. 2010;31:2015-24 pubmed publisher

product information

master code :

DKK100B

SKU :

DKK100B

product name :

Human Dkk-1 Quantikine ELISA Kit

unit size :

1 Kit

description :

The Human Dkk-1 Quantikine ELISA Kit from R&D Systems quantifies human Dkk-1 in cell culture supernates (50 ul), serum-free cell culture supernates (50 ul), serum (10 ul), platelet-poor edta plasma (50 ul), platelet-poor heparin plasma (50 ul).

target :

Dkk-1

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human Dkk-1.

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Serum-free Cell Culture Supernates (50 uL), Serum (10 uL), Platelet-poor EDTA Plasma (50 uL), Platelet-poor Heparin Plasma (50 uL)

elisaSensitivity :

0.948 pg/mL

elisaRange :

9.38 - 600 pg/mL

top caption :

Human Dkk-1 ELISA Cell Culture Supernate Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine« Human Dkk-1 immunoassay is a 4.5 hour solid phase ELISA designed to measure human Dkk-1 in cell culture supernates, serum-free cell culture supernates, serum, and platelet-poor plasma. It contains Sf 21-expressed recombinant human Dkk-1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Dkk-1 showed dose-response curves that were parallel to the standard curves obtained using the Quantikine« kit standards. These results indicate that this kit can be used to determine relative mass values of natural human Dkk-1.

alt names :

dickkopf (Xenopus laevis) homolog 1, dickkopf homolog 1 (Xenopus laevis), dickkopf related protein-1, Dickkopf-1, dickkopf-related protein 1, Dkk1, DKK-1, hDkk-1, SKdickkopf-1 like

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.