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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human GDF-15 Quantikine ELISA Kit
catalog :
DGD150
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 103
Reference
Ferreira R, Velho T, Pereira R, Pedroso D, Draiblate B, Constantino S, et al. Growth Differentiation Factor 15 as a Biomarker for Risk Stratification in the Cardiothoracic Surgery Intensive Care Unit. Biomolecules. 2024;14: pubmed publisher
Bathina S, Lopez V, Prado M, Ballato E, Colleluori G, Tetlay M, et al. Health implications of racial differences in serum growth differentiation factor levels among men with obesity. Physiol Rep. 2024;12:e70124 pubmed publisher
Ball B, Xiao W, Borthakur G, Nguyen L, Valerio M, Venkatachalam A, et al. Phase I First-in-Human Dose Escalation Study of the oral Casein Kinase 1α and Cyclin Dependent Kinase 7/9 inhibitor BTX-A51 in advanced MDS and AML. Res Sq. 2024;: pubmed publisher
Gollner A, Rudolph D, Weyer Czernilofsky U, Baumgartinger R, Jung P, Weinstabl H, et al. Discovery and Characterization of Brigimadlin, a Novel and Highly Potent MDM2-p53 Antagonist Suitable for Intermittent Dose Schedules. Mol Cancer Ther. 2024;23:1689-1702 pubmed publisher
Wang Q, Farhadipour M, Thijs T, Ruilova Sosoranga E, Van Der Schueren B, Ceulemans L, et al. Bitter-tasting drugs tune GDF15 and GLP-1 expression via bitter taste or motilin receptors in the intestine of patients with obesity. Mol Metab. 2024;88:102002 pubmed publisher
Deng J, Pan T, Wang D, Hong Y, Liu Z, Zhou X, et al. The MondoA-dependent TXNIP/GDF15 axis predicts oxaliplatin response in colorectal adenocarcinomas. EMBO Mol Med. 2024;16:2080-2108 pubmed publisher
Liu Q, Qin L, Liang Y, Xu M, Zhang J, Mo X, et al. Correlations between growth differentiation factor 15 (GDF-15) serum levels and gene polymorphism with type 2 diabetes mellitus. Heliyon. 2024;10:e33044 pubmed publisher
Nawrocka Millward S, Biegus J, Fudim M, Guzik M, Iwanek G, Ponikowski P, et al. The role of urine chloride in acute heart failure. Sci Rep. 2024;14:14100 pubmed publisher
Christidis G, K xfc ppers F, Karatayli S, Karatayli E, Weber S, Lammert F, et al. Skin advanced glycation end-products as indicators of the metabolic profile in diabetes mellitus: correlations with glycemic control, liver phenotypes and metabolic biomarkers. BMC Endocr Disord. 2024;24:31 pubmed publisher
Kim H, Kim M, Jeon J, Ham Y, Na K, Park H, et al. Association between Serum GDF-15 and Cognitive Dysfunction in Hemodialysis Patients. Biomedicines. 2024;12: pubmed publisher
Ozdemir E, Stavileci B, Ozdemir B, Aksoy F, Kahraman S, Colakoglu Gevher C, et al. The association between growth differentiation factor 15 and presence and severity of coronary atherosclerosis. Adv Med Sci. 2024;69:56-60 pubmed publisher
Shchelochkov O, Farmer C, Chlebowski C, Adedipe D, Ferry S, Manoli I, et al. Intellectual disability and autism in propionic acidemia: a biomarker-behavioral investigation implicating dysregulated mitochondrial biology. Mol Psychiatry. 2024;29:974-981 pubmed publisher
Shibasaki I, Otani N, Ouchi M, Fukuda T, Matsuoka T, Hirota S, et al. Utility of growth differentiation factor-15 as a predictor of cardiovascular surgery outcomes: Current research and future directions. J Cardiol. 2024;83:211-218 pubmed publisher
De Paepe B, Bracke K, De Bleecker J. Retrospective Study Shows That Serum Levels of Chemokine CXCL10 and Cytokine GDF15 Support a Diagnosis of Sporadic Inclusion Body Myositis and Immune-Mediated Necrotizing Myopathy. Brain Sci. 2023;13: pubmed publisher
Nederveen J, Mastrolonardo A, Xhuti D, Di Carlo A, Manta K, Fuda M, et al. Novel Multi-Ingredient Supplement Facilitates Weight Loss and Improves Body Composition in Overweight and Obese Individuals: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2023;15: pubmed publisher
Oshita T, Watanabe S, Toyohara T, Kujirai R, Kikuchi K, Suzuki T, et al. Urinary growth differentiation factor 15 predicts renal function decline in diabetic kidney disease. Sci Rep. 2023;13:12508 pubmed publisher
Wang D, Townsend L, DesOrmeaux G, Frangos S, Batchuluun B, Dumont L, et al. GDF15 promotes weight loss by enhancing energy expenditure in muscle. Nature. 2023;619:143-150 pubmed publisher
Yoshida S, Saito T, Shibagaki K, Hirao K, Yuza T, Tomosugi N, et al. Changes of biomarkers for erythropoiesis, iron metabolism, and FGF23 by supplementation with roxadustat in patients on hemodialysis. Sci Rep. 2023;13:3181 pubmed publisher
Joo M, Kim D, Lee M, Lee H, Kim J. GDF15 Promotes Cell Growth, Migration, and Invasion in Gastric Cancer by Inducing STAT3 Activation. Int J Mol Sci. 2023;24: pubmed publisher
Binder M, Yanek L, Yang W, Butcher B, Norgard S, Marine J, et al. Growth Differentiation Factor-15 Predicts Mortality and Heart Failure Exacerbation But Not Ventricular Arrhythmias in Patients With Cardiomyopathy. J Am Heart Assoc. 2023;12:e8023 pubmed publisher
Kim Muller J, Song L, LaCarubba Paulhus B, Pashos E, Li X, Rinaldi A, et al. GDF15 neutralization restores muscle function and physical performance in a mouse model of cancer cachexia. Cell Rep. 2023;42:111947 pubmed publisher
Quist J, Klein A, F xe6 rch K, Beaulieu K, Rosenkilde M, Gram A, et al. Effects of acute exercise and exercise training on plasma GDF15 concentrations and associations with appetite and cardiometabolic health in individuals with overweight or obesity - A secondary analysis of a randomized controlled trial. Appetite. 2023;182:106423 pubmed publisher
Gherghe M, Lazar A, Mutuleanu M, Bordea C, Ionescu S, Mihaila R, et al. Evaluating Cardiotoxicity in Breast Cancer Patients Treated with HER2 Inhibitors: Could a Combination of Radionuclide Ventriculography and Cardiac Biomarkers Predict the Cardiac Impact?. Cancers (Basel). 2022;15: pubmed publisher
Peterson T, Landon C, HABERLEN S, Bhondoekhan F, Plankey M, Palella F, et al. Circulating biomarker correlates of left atrial size and myocardial extracellular volume fraction among persons living with and without HIV. BMC Cardiovasc Disord. 2022;22:393 pubmed publisher
Wu L, Luo L, Zhou L, Li N, Qin X. GDF-15 and sST-2 act as biomarkers of disease severity but not independent predictors in idiopathic membranous nephropathy. Int Immunopharmacol. 2022;111:109150 pubmed publisher
Sugimoto M, Suzuki R, Nozawa Y, Takagi T, Konno N, Asama H, et al. Clinical usefulness and acceleratory effect of macrophage inhibitory cytokine-1 on biliary tract cancer: an experimental biomarker analysis. Cancer Cell Int. 2022;22:250 pubmed publisher
Torrens Mas M, Perell xf3 Reus C, Trias Ferrer N, Ibarg xfc en Gonz xe1 lez L, Cresp xed C, Galmes Panades A, et al. GDF15 and ACE2 stratify COVID-19 patients according to severity while ACE2 mutations increase infection susceptibility. Front Cell Infect Microbiol. 2022;12:942951 pubmed publisher
Luther J, Vannier A, Schaefer E, Goodman R. The circulating proteomic signature of alcohol-associated liver disease. JCI Insight. 2022;7: pubmed publisher
Kared H, Wolf A, Alirezaylavasani A, Ravussin A, Solum G, Tran T, et al. Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults. Nat Commun. 2022;13:4165 pubmed publisher
Ananthapadmanabhan V, Frost T, Soroko K, Knott A, Magliozzi B, Gokhale P, et al. Milademetan is a highly potent MDM2 inhibitor in Merkel cell carcinoma. JCI Insight. 2022;7: pubmed publisher
Arinaga Hino T, Ide T, Akiba J, Suzuki H, Kuwahara R, Amano K, et al. Growth differentiation factor 15 as a novel diagnostic and therapeutic marker for autoimmune hepatitis. Sci Rep. 2022;12:8759 pubmed publisher
Wang Y, Chen C, Chen J, Sang T, Peng H, Lin X, et al. Overexpression of NAG-1/GDF15 prevents hepatic steatosis through inhibiting oxidative stress-mediated dsDNA release and AIM2 inflammasome activation. Redox Biol. 2022;52:102322 pubmed publisher
Yamamoto H, Takeshima F, Haraguchi M, Akazawa Y, Matsushima K, Kitayama M, et al. High serum concentrations of growth differentiation factor-15 and their association with Crohn's disease and a low skeletal muscle index. Sci Rep. 2022;12:6591 pubmed publisher
Cha Y, Chang J, Kim H, Park K. Application of Mitochondrial and Oxidative Stress Biomarkers in the Evaluation of Neurocognitive Prognosis Following Acute Carbon Monoxide Poisoning. Metabolites. 2022;12: pubmed publisher
Herrmann J, Fink E, Fabio A, Au A, Berger R, Janesko Feldman K, et al. Serum levels of the cold stress hormones FGF21 and GDF-15 after cardiac arrest in infants and children enrolled in single center therapeutic hypothermia clinical trials. Resuscitation. 2022;172:173-180 pubmed publisher
Geppert J, Walth A, Terr xf3 n Exp xf3 sito R, Kaltenecker D, Morigny P, Machado J, et al. Aging Aggravates Cachexia in Tumor-Bearing Mice. Cancers (Basel). 2021;14: pubmed publisher
Nawrocka Millward S, Biegus J, Hurkacz M, Guzik M, Rosiek Biegus M, Jankowska E, et al. Differences in the Biomarker Profile of De Novo Acute Heart Failure versus Decompensation of Chronic Heart Failure. Biomolecules. 2021;11: pubmed publisher
de Sousa C, Sierra A, Mart xed nez Gal xe1 n B, Maciel J, Manoel R, Barbeiro H, et al. Time Course and Role of Exercise-Induced Cytokines in Muscle Damage and Repair After a Marathon Race. Front Physiol. 2021;12:752144 pubmed publisher
Vallet N, Delaye J, Ropert M, Foucault A, Ravalet N, Deriaz S, et al. Megaloblastic anemia-related iron overload and erythroid regulators: a case report. J Med Case Rep. 2021;15:463 pubmed publisher
Lim J, Jeon Y, Ahn J, Kim S, Kim D, Lee J, et al. GDF-15 Predicts In-Hospital Mortality of Critically Ill Patients with Acute Kidney Injury Requiring Continuous Renal Replacement Therapy: A Multicenter Prospective Study. J Clin Med. 2021;10: pubmed publisher
Lertpatipanpong P, Lee J, Kim I, Eling T, Oh S, Seong J, et al. The anti-diabetic effects of NAG-1/GDF15 on HFD/STZ-induced mice. Sci Rep. 2021;11:15027 pubmed publisher
Hong Y, Lee J, Moon H, Ryu C, Seok J, Jung Y, et al. Quercetin Induces Anticancer Activity by Upregulating Pro-NAG-1/GDF15 in Differentiated Thyroid Cancer Cells. Cancers (Basel). 2021;13: pubmed publisher
Bauer S, Demetri G, Halilovic E, Dummer R, Meille C, Tan D, et al. Pharmacokinetic-pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies. Br J Cancer. 2021;125:687-698 pubmed publisher
Kato T, Nakajima T, Fukuda T, Shibasaki I, Hasegawa T, Ogata K, et al. Preoperative Serum GDF-15, Endothelin-1 Levels, and Intraoperative Factors as Short-Term Operative Risks for Patients Undergoing Cardiovascular Surgery. J Clin Med. 2021;10: pubmed publisher
Crake R, Strother M, Phillips E, Doogue M, Zhang M, Frampton C, et al. Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study. Sci Rep. 2021;11:5648 pubmed publisher
Bening C, Sales V, Alhussini K, Radakovic D, Benitez R, Madrahimov N, et al. Clinically inapparent right heart dysfunction is associated with reduced myofilament force development in coronary artery disease. BMC Cardiovasc Disord. 2021;21:125 pubmed publisher
Liu H, Huang Y, Lyu Y, Dai W, Tong Y, Li Y. GDF15 as a biomarker of ageing. Exp Gerontol. 2021;146:111228 pubmed publisher
de Cos Gomez M, Benito Hernández A, Garcia Unzueta M, Mazon Ruiz J, López Del Moral Cuesta C, Perez Canga J, et al. Growth Differentiation Factor 15: A Biomarker with High Clinical Potential in the Evaluation of Kidney Transplant Candidates. J Clin Med. 2020;9: pubmed publisher
Guinot P, Ellouze O, Grosjean S, Berthoud V, Constandache T, Radhouani M, et al. Anaesthesia and ICU sedation with sevoflurane do not reduce myocardial injury in patients undergoing cardiac surgery: A randomized prospective study. Medicine (Baltimore). 2020;99:e23253 pubmed publisher
Oikawa Y, Izumi R, Koide M, Hagiwara Y, Kanzaki M, Suzuki N, et al. Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5. PLoS ONE. 2020;15:e0231064 pubmed publisher
Chung J, Park S, Cho D, Chung D, Chung M. Relationship between plasma growth differentiation factor-15 levels and diabetic retinopathy in individuals with type 2 diabetes. Sci Rep. 2020;10:20568 pubmed publisher
Zhao Z, Zhang J, Yin L, Yang J, Zheng Y, Zhang M, et al. Upregulated GDF-15 expression facilitates pancreatic ductal adenocarcinoma progression through orphan receptor GFRAL. Aging (Albany NY). 2020;12:22564-22581 pubmed publisher
Wada H, Suzuki M, Matsuda M, Ajiro Y, Shinozaki T, Sakagami S, et al. Impact of Smoking Status on Growth Differentiation Factor 15 and Mortality in Patients With Suspected or Known Coronary Artery Disease: The ANOX Study. J Am Heart Assoc. 2020;9:e018217 pubmed publisher
Yazawa H, Fukuda T, Kaneda H, Waku R, Sakuma M, Matsumoto A, et al. Association of serum growth differentiation factor-15 with eGFR and hemoglobin in healthy older females. Int J Cardiol Heart Vasc. 2020;31:100651 pubmed publisher
Izaguirre D, Ng C, Kwan S, Kun E, Tsang Y, Gershenson D, et al. The Role of GDF15 in Regulating the Canonical Pathways of the Tumor Microenvironment in Wild-Type p53 Ovarian Tumor and Its Response to Chemotherapy. Cancers (Basel). 2020;12: pubmed publisher
Kim H, Kim K, Kang M, Lim S. Growth differentiation factor-15 as a biomarker for sarcopenia in aging humans and mice. Exp Gerontol. 2020;142:111115 pubmed publisher
Hannappe M, Arnould L, Meloux A, Mouhat B, Bichat F, Zeller M, et al. Vascular density with optical coherence tomography angiography and systemic biomarkers in low and high cardiovascular risk patients. Sci Rep. 2020;10:16718 pubmed publisher
Van Dyck L, Gunst J, Casaer M, Peeters B, Derese I, Wouters P, et al. The clinical potential of GDF15 as a "ready-to-feed indicator" for critically ill adults. Crit Care. 2020;24:557 pubmed publisher
Freeman D, Noren Hooten N, Kim Y, Mode N, Ejiogu N, Zonderman A, et al. Association between GDF15, poverty and mortality in urban middle-aged African American and white adults. PLoS ONE. 2020;15:e0237059 pubmed publisher
Domínguez González C, Badosa C, Madruga Garrido M, Marti I, Paradas C, Ortez C, et al. Growth Differentiation Factor 15 is a potential biomarker of therapeutic response for TK2 deficient myopathy. Sci Rep. 2020;10:10111 pubmed publisher
Borner T, Wald H, Ghidewon M, Zhang B, Wu Z, De Jonghe B, et al. GDF15 Induces an Aversive Visceral Malaise State that Drives Anorexia and Weight Loss. Cell Rep. 2020;31:107543 pubmed publisher
Mitic V, Stojanovic D, Deljanin Ilic M, Stojanovic M, Petrovic D, Ignjatović A, et al. Cardiac Remodeling Biomarkers as Potential Circulating Markers of Left Ventricular Hypertrophy in Heart Failure with Preserved Ejection Fraction. Tohoku J Exp Med. 2020;250:233-242 pubmed publisher
De Jesus D, Orime K, Kaminska D, Kimura T, Basile G, Wang C, et al. Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice. J Clin Invest. 2020;130:2391-2407 pubmed publisher
Kagiyama Y, Yatsuga S, Kinoshita M, Koteda Y, Kishimoto S, Koga Y, et al. Growth differentiation factor 15 as a useful biomarker of heart failure in young patients with unrepaired congenital heart disease of left to right shunt. J Cardiol. 2020;75:697-701 pubmed publisher
Noren Hooten N, McFarland M, Freeman D, Mode N, Ezike N, Zonderman A, et al. Association of Extracellular Vesicle Protein Cargo with Race and Clinical Markers of Mortality. Sci Rep. 2019;9:17582 pubmed publisher
Nakajima T, Shibasaki I, Sawaguchi T, Haruyama A, Kaneda H, Nakajima T, et al. Growth Differentiation Factor-15 (GDF-15) is a Biomarker of Muscle Wasting and Renal Dysfunction in Preoperative Cardiovascular Surgery Patients. J Clin Med. 2019;8: pubmed publisher
Chen G, Wang M, Liu X. GDF15 promotes osteosarcoma cell migration and invasion by regulating the TGF‑β signaling pathway. Mol Med Rep. 2019;20:4262-4270 pubmed publisher
Richter B, Uray T, Krychtiuk K, Schriefl C, Lenz M, Nürnberger A, et al. Growth differentiation factor-15 predicts poor survival after cardiac arrest. Resuscitation. 2019;143:22-28 pubmed publisher
Miyauchi A, Kouga T, Jimbo E, Matsuhashi T, Abe T, Yamagata T, et al. Apomorphine rescues reactive oxygen species-induced apoptosis of fibroblasts with mitochondrial disease. Mitochondrion. 2019;49:111-120 pubmed publisher
Traeger L, Ellermann I, Wiethoff H, Ihbe J, Gallitz I, Eveslage M, et al. Serum Hepcidin and GDF-15 levels as prognostic markers in urothelial carcinoma of the upper urinary tract and renal cell carcinoma. BMC Cancer. 2019;19:74 pubmed publisher
Engerud H, Hope K, Berg H, Fasmer K, Tangen I, Haldorsen I, et al. Plasma growth differentiation factor-15 is an independent marker for aggressive disease in endometrial cancer. PLoS ONE. 2019;14:e0210585 pubmed publisher
Wu C, Su M, Wu Y, Hwang J, Lin L. Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients. J Clin Med. 2018;7: pubmed publisher
Jeay S, Ferretti S, Holzer P, Fuchs J, Chapeau E, Wartmann M, et al. Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53-MDM2 Inhibitor HDM201. Cancer Res. 2018;78:6257-6267 pubmed publisher
Sun L, Zhou X, Jiang J, Zang X, Chen X, Li H, et al. Growth differentiation factor-15 levels and the risk of contrast induced nephropathy in patients with acute myocardial infarction undergoing percutaneous coronary intervention: A retrospective observation study. PLoS ONE. 2018;13:e0197609 pubmed publisher
Babic A, Schnure N, Neupane N, Zaman M, Rifai N, Welch M, et al. Plasma inflammatory cytokines and survival of pancreatic cancer patients. Clin Transl Gastroenterol. 2018;9:145 pubmed publisher
Ham Y, Song C, Bae H, Jeong J, Yeo M, Choi D, et al. Growth Differentiation Factor-15 as a Predictor of Idiopathic Membranous Nephropathy Progression: A Retrospective Study. Dis Markers. 2018;2018:1463940 pubmed publisher
Li S, Ma Y, Zheng P, Zhang P. GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2. J Exp Clin Cancer Res. 2018;37:80 pubmed publisher
Scherzer R, Shah S, Secemsky E, Butler J, Grunfeld C, Shlipak M, et al. Association of Biomarker Clusters With Cardiac Phenotypes and Mortality in Patients With HIV Infection. Circ Heart Fail. 2018;11:e004312 pubmed publisher
Sun L, Zhou X, Jiang J, Zang X, Chen X, Li H, et al. Growth differentiation factor-15 levels and the risk of contrast induced acute kidney injury in acute myocardial infarction patients treated invasively: A propensity-score match analysis. PLoS ONE. 2018;13:e0194152 pubmed publisher
Kleinert M, Clemmensen C, Sjøberg K, Carl C, Jeppesen J, Wojtaszewski J, et al. Exercise increases circulating GDF15 in humans. Mol Metab. 2018;9:187-191 pubmed publisher
Stojkovic S, Kaider A, Koller L, Brekalo M, Wojta J, Diedrich A, et al. GDF-15 is a better complimentary marker for risk stratification of arrhythmic death in non-ischaemic, dilated cardiomyopathy than soluble ST2. J Cell Mol Med. 2018;22:2422-2429 pubmed publisher
Buendgens L, Yagmur E, Bruensing J, Herbers U, Baeck C, Trautwein C, et al. Growth Differentiation Factor-15 Is a Predictor of Mortality in Critically Ill Patients with Sepsis. Dis Markers. 2017;2017:5271203 pubmed publisher
Ratnam N, Peterson J, Talbert E, Ladner K, Rajasekera P, Schmidt C, et al. NF-?B regulates GDF-15 to suppress macrophage surveillance during early tumor development. J Clin Invest. 2017;127:3796-3809 pubmed publisher
Sugimoto M, Takagi T, Konno N, Suzuki R, Asama H, Watanabe K, et al. The efficacy of biliary and serum macrophage inhibitory cytokine-1 for diagnosing biliary tract cancer. Sci Rep. 2017;7:9198 pubmed publisher
Matsuhashi T, Sato T, Kanno S, Suzuki T, Matsuo A, Oba Y, et al. Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases. EBioMedicine. 2017;20:27-38 pubmed publisher
Ban N, Siegfried C, Lin J, Shui Y, Sein J, Pita Thomas W, et al. GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients. JCI Insight. 2017;2: pubmed publisher
Yang Y, Lian S, Meng L, Qu L, Shou C. Antibody Array Revealed PRL-3 Affects Protein Phosphorylation and Cytokine Secretion. PLoS ONE. 2017;12:e0169665 pubmed publisher
Schernthaner Reiter M, Kasses D, Tugendsam C, Riedl M, Peric S, Prager G, et al. Growth differentiation factor 15 increases following oral glucose ingestion: effect of meal composition and obesity. Eur J Endocrinol. 2016;175:623-631 pubmed
Yuan Z, Li H, Qi Q, Gong W, Qian C, Dong R, et al. Plasma levels of growth differentiation factor-15 are associated with myocardial injury in patients undergoing off-pump coronary artery bypass grafting. Sci Rep. 2016;6:28221 pubmed publisher
Mahon K, Lin H, Castillo L, Lee B, Lee Ng M, Chatfield M, et al. Cytokine profiling of docetaxel-resistant castration-resistant prostate cancer. Br J Cancer. 2015;112:1340-8 pubmed publisher
Urakawa N, Utsunomiya S, Nishio M, Shigeoka M, Takase N, Arai N, et al. GDF15 derived from both tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression via Akt and Erk pathways. Lab Invest. 2015;95:491-503 pubmed publisher
Jeansonne D, DeLuca M, Marrero L, Lassak A, Pacifici M, Wyczechowska D, et al. Anti-tumoral effects of miR-3189-3p in glioblastoma. J Biol Chem. 2015;290:8067-80 pubmed publisher
Kahli A, Guenancia C, Zeller M, Grosjean S, Stamboul K, Rochette L, et al. Growth differentiation factor-15 (GDF-15) levels are associated with cardiac and renal injury in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass. PLoS ONE. 2014;9:e105759 pubmed publisher
Fujiwara T, Ikeda T, Nagasaka Y, Okitsu Y, Katsuoka Y, Fukuhara N, et al. A low-molecular-weight compound K7174 represses hepcidin: possible therapeutic strategy against anemia of chronic disease. PLoS ONE. 2013;8:e75568 pubmed publisher
André T, Meuleman N, Stamatopoulos B, De Bruyn C, Pieters K, Bron D, et al. Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells. PLoS ONE. 2013;8:e59756 pubmed publisher
Aksoy C, Guliyev A, Kilic E, Uckan D, Severcan F. Bone marrow mesenchymal stem cells in patients with beta thalassemia major: molecular analysis with attenuated total reflection-Fourier transform infrared spectroscopy study as a novel method. Stem Cells Dev. 2012;21:2000-11 pubmed publisher
Talbot N, Lakhal S, Smith T, Privat C, Nickol A, Rivera Ch M, et al. Regulation of hepcidin expression at high altitude. Blood. 2012;119:857-60 pubmed publisher
Si Y, Liu X, Cheng M, Wang M, Gong Q, Yang Y, et al. Growth differentiation factor 15 is induced by hepatitis C virus infection and regulates hepatocellular carcinoma-related genes. PLoS ONE. 2011;6:e19967 pubmed publisher
Wei J, Wu A, Kong L, Wang Y, Fuller G, Fokt I, et al. Hypoxia potentiates glioma-mediated immunosuppression. PLoS ONE. 2011;6:e16195 pubmed publisher
Vila G, Riedl M, Anderwald C, Resl M, Handisurya A, Clodi M, et al. The relationship between insulin resistance and the cardiovascular biomarker growth differentiation factor-15 in obese patients. Clin Chem. 2011;57:309-16 pubmed publisher
Piperno A, Galimberti S, Mariani R, Pelucchi S, Ravasi G, Lombardi C, et al. Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project. Blood. 2011;117:2953-9 pubmed publisher
Darmanis S, Nong R, Hammond M, Gu J, Alderborn A, Vänelid J, et al. Sensitive plasma protein analysis by microparticle-based proximity ligation assays. Mol Cell Proteomics. 2010;9:327-35 pubmed publisher
Ashby D, Gale D, Busbridge M, Murphy K, Duncan N, Cairns T, et al. Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease. Kidney Int. 2009;75:976-81 pubmed publisher
product information
master code :
DGD150
SKU :
DGD150
product name :
Human GDF-15 Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Human GDF-15 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human GDF-15 in cell culture supernates (50 ul), serum (13 ul), edta plasma (13 ul), heparin plasma (13 ul), urine (10 ul).
target :
GDF-15
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human GDF-15
gene symbol :
GDF15
kit type :
Solid Phase Sandwich ELISA
assay length :
3.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (13 uL), EDTA Plasma (13 uL), Heparin Plasma (13 uL), Urine (10 uL)
elisaSensitivity :
4.39 pg/mL
elisaRange :
23.40 - 1500 pg/mL
top caption :
Human GDF-15 Quantikine ELISA Kit Linearity Competitor Comparison
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human GDF-15 immunoassay is a 3.5 hour solid phase ELISA designed to measure GDF-15 in cell culture supernates, serum, plasma, and urine. It contains CHO cell-expressed recombinant human GDF-15 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural GDF-15 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of naturally occurring GDF-15.
alt names :
GDF15, growth differentiation factor 15, growth/differentiation factor 15, Macrophage inhibitory cytokine 1, MIC-1, MIC-1NSAID-activated gene 1 protein, MIC1Prostate differentiation factor, NAG-1, NAG-1NSAID-regulated gene 1 protein, NSAID (nonsteroidal inflammatory drug)-activated protein 1, PDF, PDFGDF-15, PLAB, PLABNRG-1, Placental bone morphogenetic protein, Placental TGF-beta, PTGF-beta, PTGFBPTGF-beta
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.