Human Fas Ligand/TNFSF6 Quantikine ELISA Kit | R&D Systems DFL00B product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human Fas Ligand/TNFSF6 Quantikine ELISA Kit

catalog :

DFL00B

quantity :

1 Kit

price :

655 USD

citations: 30

Reference
Pourfarzam S, Ardestani S, Jamali T, Ghazanfari H, Naghizadeh M, Faghihzadeh S, et al. Distinct inflammatory profiles in mustard lung: A study of sulfur mustard-exposed patients with serious pulmonary complications. Int Immunopharmacol. 2025;146:113832 pubmed publisher
Thaler F, Bangol B, Biljecki M, Havla J, Schumacher A, Kümpfel T. Possible link of genetic variants to autoimmunity in GAD-antibody-associated neurological disorders. J Neurol Sci. 2020;413:116860 pubmed publisher
Masuda A, Isobe Y, Sugimoto K, Yoshimori M, Arai A, Komatsu N. Efficient recruitment of c-FLIPL to the death-inducing signaling complex leads to Fas resistance in natural killer-cell lymphoma. Cancer Sci. 2020;111:807-816 pubmed publisher
Grzanka R, Damasiewicz Bodzek A, Kasperska Zajac A. Tumor necrosis factor-alpha and Fas/Fas ligand signaling pathways in chronic spontaneous urticaria. Allergy Asthma Clin Immunol. 2019;15:15 pubmed publisher
Matsukiyo Y, Nagai H, Matsui T, Igarashi Y. Host Immunological Effects of Partial Splenic Embolization in Patients with Liver Cirrhosis. J Immunol Res. 2018;2018:1746391 pubmed publisher
Karowicz Bilinska A, Kowalska Koprek U, Estemberg D, Sikora Szubert A. Evaluation of soluble concentration Fas and Fas ligand in maternal and cord blood 3rd trimester of pregnancy. Ginekol Pol. 2018;89:142-146 pubmed publisher
Chang L, Li Y, Kaplan D. Endotoxemia contributes to CD27+ memory B-cell apoptosis via enhanced sensitivity to Fas ligation in patients with Cirrhosis. Sci Rep. 2016;6:36862 pubmed publisher
Katz G, Krummey S, Larsen S, Stinson J, Snow A. SAP facilitates recruitment and activation of LCK at NTB-A receptors during restimulation-induced cell death. J Immunol. 2014;192:4202-9 pubmed publisher
Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, et al. Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation. J Biol Chem. 2014;289:11522-35 pubmed publisher
Price S, Shaw P, Seitz A, Joshi G, Davis J, Niemela J, et al. Natural history of autoimmune lymphoproliferative syndrome associated with FAS gene mutations. Blood. 2014;123:1989-99 pubmed publisher
Beynon V, Quintana F, Weiner H. Activated human CD4+CD45RO+ memory T-cells indirectly inhibit NLRP3 inflammasome activation through downregulation of P2X7R signalling. PLoS ONE. 2012;7:e39576 pubmed publisher
Bellini A, Marini M, Bianchetti L, Barczyk M, Schmidt M, Mattoli S. Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients. Mucosal Immunol. 2012;5:140-9 pubmed publisher
Tang T, Zhu Z, Wang J, Zhang W, Tu X, Xiao H, et al. Impaired thymic export and apoptosis contribute to regulatory T-cell defects in patients with chronic heart failure. PLoS ONE. 2011;6:e24272 pubmed publisher
Dowdell K, Niemela J, Price S, Davis J, Hornung R, Oliveira J, et al. Somatic FAS mutations are common in patients with genetically undefined autoimmune lymphoproliferative syndrome. Blood. 2010;115:5164-9 pubmed publisher
Deftereos S, Giannopoulos G, Kossyvakis C, Kaoukis A, Raisakis K, Driva M, et al. Effect of quinapril on in-stent restenosis and relation to plasma apoptosis signaling molecules. Am J Cardiol. 2010;105:54-8 pubmed publisher
Zhao W, Xu L, Wang L, Zhang L, Zhang Z, Liu Y, et al. A 60-s postconditioning protocol by percutaneous coronary intervention inhibits myocardial apoptosis in patients with acute myocardial infarction. Apoptosis. 2009;14:1204-11 pubmed publisher
Liao W, Yu C, Lan C, Lee C, Chang C, Chang L, et al. Differential effects of arsenic on cutaneous and systemic immunity: focusing on CD4+ cell apoptosis in patients with arsenic-induced Bowen's disease. Carcinogenesis. 2009;30:1064-72 pubmed publisher
Tohyama M, Shirakata Y, Sayama K, Hashimoto K. The influence of hepatic damage on serum soluble Fas ligand levels of patients with drug rashes. J Allergy Clin Immunol. 2009;123:971-2; author reply 972 pubmed publisher
Dai Z, Turtle C, Booth G, Riddell S, Gooley T, Stevens A, et al. Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus. J Exp Med. 2009;206:793-805 pubmed publisher
Chung W, Hung S, Yang J, Su S, Huang S, Wei C, et al. Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. Nat Med. 2008;14:1343-50 pubmed publisher
Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, et al. Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp Hematol. 2008;36:1035-46 pubmed publisher
Kourea K, Parissis J, Farmakis D, Panou F, Paraskevaidis I, Venetsanou K, et al. Effects of darbepoetin-alpha on plasma pro-inflammatory cytokines, anti-inflammatory cytokine interleukin-10 and soluble Fas/Fas ligand system in anemic patients with chronic heart failure. Atherosclerosis. 2008;199:215-21 pubmed
Zhang B, Sun T, Xue L, Han X, Zhang B, Lu N, et al. Functional polymorphisms in FAS and FASL contribute to increased apoptosis of tumor infiltration lymphocytes and risk of breast cancer. Carcinogenesis. 2007;28:1067-73 pubmed
Harris L, Keogh R, Wareing M, Baker P, Cartwright J, Aplin J, et al. Invasive trophoblasts stimulate vascular smooth muscle cell apoptosis by a fas ligand-dependent mechanism. Am J Pathol. 2006;169:1863-74 pubmed
Claessens Y, Fontenay M, Pène F, Chiche J, Guesnu M, Hababou C, et al. Erythropoiesis abnormalities contribute to early-onset anemia in patients with septic shock. Am J Respir Crit Care Med. 2006;174:51-7 pubmed
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product information

master code :

DFL00B

SKU :

DFL00B

product name :

Human Fas Ligand/TNFSF6 Quantikine ELISA Kit

unit size :

1 Kit

description :

The Human Fas Ligand/TNFSF6 Quantikine ELISA Kit from R&D Systems quantifies human Fas Ligand/TNFSF6 in cell culture supernates (50 ul), cell lysates (50 ul), serum (50 ul), edta plasma (50 ul), heparin plasma (50 ul).

target :

Fas Ligand/TNFSF6

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human Fas Ligand.

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Cell Lysates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)

elisaSensitivity :

5.1 pg/mL

elisaRange :

15.60 - 1000 pg/mL

top caption :

Human Fas Ligand/TNFSF6 Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine« Human Fas Ligand/TNFSF6 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Fas Ligand in cell culture supernates, cell lysates, serum, and plasma. It contains CHO cell-expressed recombinant human Fas Ligand and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Fas Ligand showed linear curves that were parallel to the standard curves obtained using the Quantikine« kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Fas Ligand.

alt names :

apoptosis (APO-1) antigen ligand 1, Apoptosis antigen ligand, APT1LG1CD95L, APTL, CD178, CD178 antigen, CD95L, CD95-L, Fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, member 6), FASLCD95 ligand, FASLG, TNFSF6, TNFSF6FasL, tumor necrosis factor (ligand) superfamily, member 6, tumor necrosis factor ligand superfamily member 6

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.