Human Flt-3 Ligand/FLT3L Quantikine ELISA Kit | R&D Systems DFK00 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human Flt-3 Ligand/FLT3L Quantikine ELISA Kit

catalog :

DFK00

quantity :

1 Kit

price :

655 USD

citations: 21

Reference
Detjen K, Otto R, Giesecke Y, Geisler L, Riemer P, Jann H, et al. Elevated Flt3L Predicts Long-Term Survival in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms. Cancers (Basel). 2021;13: pubmed publisher
Loughland J, Woodberry T, Oyong D, Piera K, Amante F, Barber B, et al. Reduced circulating dendritic cells in acute Plasmodium knowlesi and Plasmodium falciparum malaria despite elevated plasma Flt3 ligand levels. Malar J. 2021;20:97 pubmed publisher
Saevarsdottir S, Olafsdottir T, Ivarsdottir E, Halldorsson G, Gunnarsdottir K, Sigurdsson A, et al. FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease. Nature. 2020;584:619-623 pubmed publisher
Kawase T, Nakazawa T, Eguchi T, Tsuzuki H, Ueno Y, Amano Y, et al. Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells. Oncotarget. 2019;10:6111-6123 pubmed publisher
Yuan Y, Zhou C, Yang Q, Ma S, Wang X, Guo X, et al. HIV-1 Tat protein inhibits the hematopoietic support function of human bone marrow mesenchymal stem cells. Virus Res. 2019;273:197756 pubmed publisher
Yuan X, Qin X, Wang D, Zhang Z, Tang X, Gao X, et al. Mesenchymal stem cell therapy induces FLT3L and CD1c+ dendritic cells in systemic lupus erythematosus patients. Nat Commun. 2019;10:2498 pubmed publisher
Kalanxhi E, Meltzer S, Schou J, Larsen F, Dueland S, Flatmark K, et al. Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer. Br J Cancer. 2018;118:1322-1328 pubmed publisher
Batsali A, Pontikoglou C, Koutroulakis D, Pavlaki K, Damianaki A, Mavroudi I, et al. Differential expression of cell cycle and WNT pathway-related genes accounts for differences in the growth and differentiation potential of Wharton's jelly and bone marrow-derived mesenchymal stem cells. Stem Cell Res Ther. 2017;8:102 pubmed publisher
Ciullini Mannurita S, Vignoli M, Colarusso G, Tucci F, Veltroni M, Frenos S, et al. Timely follow-up of a GATA2 deficiency patient allows successful treatment. J Allergy Clin Immunol. 2016;138:1480-1483.e4 pubmed publisher
Nguyen T, Arthur A, Panagopoulos R, Paton S, Hayball J, Zannettino A, et al. EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance. Stem Cells. 2015;33:2838-49 pubmed publisher
Xiong W, Candolfi M, Liu C, Muhammad A, Yagiz K, Puntel M, et al. Human Flt3L generates dendritic cells from canine peripheral blood precursors: implications for a dog glioma clinical trial. PLoS ONE. 2010;5:e11074 pubmed publisher
Reeves R, Wei Q, Stallworth J, Fultz P. Systemic dendritic cell mobilization associated with administration of FLT3 ligand to SIV- and SHIV-infected macaques. AIDS Res Hum Retroviruses. 2009;25:1313-28 pubmed publisher
Hatfield K, Ryningen A, Corbascio M, Bruserud O. Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts. Int J Cancer. 2006;119:2313-21 pubmed
Iłzecka J. Cerebrospinal fluid Flt3 ligand level in patients with amyotrophic lateral sclerosis. Acta Neurol Scand. 2006;114:205-9 pubmed
Curtin J, King G, Barcia C, Liu C, Hubert F, Guillonneau C, et al. Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain. J Immunol. 2006;176:3566-77 pubmed
Ali S, Curtin J, Zirger J, Xiong W, King G, Barcia C, et al. Inflammatory and anti-glioma effects of an adenovirus expressing human soluble Fms-like tyrosine kinase 3 ligand (hsFlt3L): treatment with hsFlt3L inhibits intracranial glioma progression. Mol Ther. 2004;10:1071-84 pubmed
Drouet M, Mourcin F, Grenier N, Leroux V, Denis J, Mayol J, et al. Single administration of stem cell factor, FLT-3 ligand, megakaryocyte growth and development factor, and interleukin-3 in combination soon after irradiation prevents nonhuman primates from myelosuppression: long-term follow-up of hematopoiesis. Blood. 2004;103:878-85 pubmed
Haidar J, Bazarbachi A, Mahfouz R, Haidar H, Jaafar H, Daher R. Serum Flt3 ligand variation as a predictive indicator of hematopoietic stem cell mobilization. J Hematother Stem Cell Res. 2002;11:533-8 pubmed
Briard D, Brouty Boye D, Azzarone B, Jasmin C. Fibroblasts from human spleen regulate NK cell differentiation from blood CD34(+) progenitors via cell surface IL-15. J Immunol. 2002;168:4326-32 pubmed
Loeuillet C, Bernard G, Remy Martin J, Saas P, Herve P, Douay L, et al. Distinct hematopoietic support by two human stromal cell lines. Exp Hematol. 2001;29:736-45 pubmed
Solanilla A, Dechanet J, El Andaloussi A, Dupouy M, Godard F, Chabrol J, et al. CD40-ligand stimulates myelopoiesis by regulating flt3-ligand and thrombopoietin production in bone marrow stromal cells. Blood. 2000;95:3758-64 pubmed

product information

master code :

DFK00

SKU :

DFK00

product name :

Human Flt-3 Ligand/FLT3L Quantikine ELISA Kit

unit size :

1 Kit

description :

The Human Flt-3 Ligand/FLT3L Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human Flt-3 Ligand/FLT3L in cell culture supernates (50 ul), serum (50 ul), edta plasma (50 ul), heparin plasma (50 ul), citrate plasma (50 ul).

target :

Flt-3 Ligand/FLT3L

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human Flt-3 Ligand

gene symbol :

FLT3LG

kit type :

Solid Phase Sandwich ELISA

assay length :

4 hours or 4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL), Citrate Plasma (50 uL)

elisaSensitivity :

7 pg/mL

elisaRange :

15.60 - 1000 pg/mL

top caption :

Human Flt-3 Ligand ELISA Cell Culture Supernate Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human Flt-3/Flk-2 Ligand Immunoassay is a 4.0 or 4.5 hour solid phase ELISA designed to measure soluble human Flt-3 Ligand in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human Flt-3 Ligand and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant Flt-3 Ligand accurately. Results obtained measuring natural human Flt-3 Ligand showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Flt-3 Ligand.

alt names :

FL, FLG3L, Flt3 ligand, Flt3L, FLT3LG, fms-related tyrosine kinase 3 ligand, SL cytokine

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.