product summary
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company name :
R&D Systems
product type :
ELISA/assay
product name :
Endothelin-1 Quantikine ELISA Kit
catalog :
DET100
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
more info or order :
citations: 87
Reference
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Totaro P, Tirelli C, De Amici M, Grosjean F, Testa G, Sacchi L, et al. Circulating Endothelin 1 but Not Transforming Growth Factor-β Levels Are Reduced after Pulmonary Endarterectomy in Subjects Affected by Chronic Thromboembolic Pulmonary Hypertension: A Prospective Cohort Study. J Clin Med. 2024;13: pubmed publisher
Gonsalves A, Baker S, Jacob D, Harper J, Manrique Acevedo C, Limberg J. Effect of endothelin-1 on the blood pressure response to acute hypoxia and hyperoxia in healthy young men. Physiol Rep. 2024;12:e70004 pubmed publisher
Ho x142 da M, Ra x17a ny U, Sordyl M, G xf3 ralska J, Kapusta M, S x142 owi x144 ska Solnica K, et al. Autophagy and ubiquitin-dependent proteolysis processes in left ventricular mass loss in pulmonary arterial hypertension. Sci Rep. 2024;14:15133 pubmed publisher
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Pulito Cueto V, Genre F, L xf3 pez Mej xed as R, Mora Cuesta V, Iturbe Fern xe1 ndez D, Portilla V, et al. Endothelin-1 as a Biomarker of Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Associated with Autoimmune Diseases. Int J Mol Sci. 2023;24: pubmed publisher
Tocci P, Román C, Sestito R, Di Castro V, Sacconi A, Molineris I, et al. Targeting tumor-stroma communication by blocking endothelin-1 receptors sensitizes high-grade serous ovarian cancer to PARP inhibition. Cell Death Dis. 2023;14:5 pubmed publisher
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Weigert A, Zheng X, Nenzel A, Turkowski K, G xfc nther S, Strack E, et al. Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. Nat Commun. 2022;13:6078 pubmed publisher
Fato B, De Alwis N, Beard S, Binder N, Pritchard N, Tong S, et al. Serum Collected from Preeclamptic Pregnancies Drives Vasoconstriction of Human Omental Arteries-A Novel Ex Vivo Model of Preeclampsia for Therapeutic Development. Int J Mol Sci. 2022;23: pubmed publisher
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De Alwis N, Binder N, Mangwiro Y, Beard S, Pritchard N, Kadife E, et al. Actions of Esomeprazole on the Maternal Vasculature in Lean and Obese Pregnant Mice with Impaired Nitric Oxide Synthesis: A Model of Preeclampsia. Int J Mol Sci. 2022;23: pubmed publisher
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Lommatzsch C, Rothaus K, Schopmeyer L, Feldmann M, Bauer D, Grisanti S, et al. Elevated endothelin-1 levels as risk factor for an impaired ocular blood flow measured by OCT-A in glaucoma. Sci Rep. 2022;12:11801 pubmed publisher
Baran J, Niewiara x, Podolec J, Siedli x144 ski M, J xf3 zefczuk E, Bernacik A, et al. Serum and Vascular Stiffness Biomarkers Associated with the Severity of Degenerative Aortic Valve Stenosis and Cardiovascular Outcomes. J Cardiovasc Dev Dis. 2022;9: pubmed publisher
MacDonald S, Bosio E, Shapiro N, Balmer L, Burrows S, Hibbs M, et al. No association between intravenous fluid volume and endothelial glycocalyx shedding in patients undergoing resuscitation for sepsis in the emergency department. Sci Rep. 2022;12:8733 pubmed publisher
Kang H, Hasanuzzaman M, Kim S, Koh H, Lee S. Elevated aqueous endothelin-1 concentrations in advanced diabetic retinopathy. PLoS ONE. 2022;17:e0268353 pubmed publisher
Yang X, Dai R, Qin Z, Cai R, Xu Y, Su Q. LncRNA MALAT1 functions as a biomarker of no-reflow phenomenon in ST-segment elevation myocardial infarction patients receiving primary percutaneous coronary intervention. Sci Rep. 2022;12:3294 pubmed publisher
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Vong C, Chen Y, Chen Z, Gao C, Yang F, Wang S, et al. Classical prescription Dachuanxiong Formula delays nitroglycerin-induced pain response in migraine mice through reducing endothelin-1 level and regulating fatty acid biosynthesis. J Ethnopharmacol. 2022;288:114992 pubmed publisher
Nie X, Shen C, Tan J, Yang X, Wang W, Dai Y, et al. Andrographolide Attenuates Established Pulmonary Hypertension via Rescue of Vascular Remodeling. Biomolecules. 2021;11: pubmed publisher
Velásquez M, Peláez L, Rojas M, Narvaez Sanchez R, Velásquez J, Escudero C, et al. Differences in Endothelial Activation and Dysfunction Induced by Antiphospholipid Antibodies Among Groups of Patients With Thrombotic, Refractory, and Non-refractory Antiphospholipid Syndrome. Front Physiol. 2021;12:764702 pubmed publisher
Dakota I, Munawar M, Pranata R, Raffaello W, Sukmawan R. Diagnostic prediction model in subjects with low-risk unstable angina pectoris/non-ST segment Elevation Myocardial Infarction. Eur Rev Med Pharmacol Sci. 2021;25:5145-5152 pubmed publisher
Ríos Arrabal S, Puentes Pardo J, Moreno SanJuan S, Szuba A, Casado J, García Costela M, et al. Endothelin-1 as a Mediator of Heme Oxygenase-1-Induced Stemness in Colorectal Cancer: Influence of p53. J Pers Med. 2021;11: pubmed publisher
Kang H, Hasanuzzaman M, Kim S, Koh H, Lee S. Significant elevation of aqueous endothelin-1 in central retinal vein occlusion. PLoS ONE. 2021;16:e0252530 pubmed publisher
Nassar E, Hassan N, El Ghonaimy E, Hassan H, Abdullah M, Rottke T, et al. Syndecan-1 Promotes Angiogenesis in Triple-Negative Breast Cancer through the Prognostically Relevant Tissue Factor Pathway and Additional Angiogenic Routes. Cancers (Basel). 2021;13: pubmed publisher
Kato T, Nakajima T, Fukuda T, Shibasaki I, Hasegawa T, Ogata K, et al. Preoperative Serum GDF-15, Endothelin-1 Levels, and Intraoperative Factors as Short-Term Operative Risks for Patients Undergoing Cardiovascular Surgery. J Clin Med. 2021;10: pubmed publisher
Payne G, Sharma N, Lal C, Song C, Guo L, Margaroli C, et al. Prolyl endopeptidase contributes to early neutrophilic inflammation in acute myocardial transplant rejection. JCI Insight. 2021;6: pubmed publisher
Osawa Y, Yoshio S, Aoki Y, Korenaga M, Imamura M, Oide T, et al. Blood angiopoietin-2 predicts liver angiogenesis and fibrosis in hepatitis C patients. BMC Gastroenterol. 2021;21:55 pubmed publisher
Figueiredo C, Santiago R, da Guarda C, Oliveira R, Fiuza L, Yahouedehou S, et al. Priapism in sickle cell disease: Associations between NOS3 and EDN1 genetic polymorphisms and laboratory biomarkers. PLoS ONE. 2021;16:e0246067 pubmed publisher
Yu Q, Li K, Zhao A, Wei M, Huang Z, Zhang Y, et al. Sorafenib not only impairs endothelium-dependent relaxation but also promotes vasoconstriction through the upregulation of vasoconstrictive endothelin type B receptors. Toxicol Appl Pharmacol. 2021;414:115420 pubmed publisher
Monroe J, Song Q, Emery M, Hirai D, Motaganahalli R, Roseguini B. Acute effects of leg heat therapy on walking performance and cardiovascular and inflammatory responses to exercise in patients with peripheral artery disease. Physiol Rep. 2021;8:e14650 pubmed publisher
Santiago R, Figueiredo C, Fiuza L, Yahouedehou S, Oliveira R, Aleluia M, et al. TGFBR3 Polymorphisms (rs1805110 and rs7526590) Are Associated with Laboratory Biomarkers and Clinical Manifestations in Sickle Cell Anemia. Dis Markers. 2020;2020:8867986 pubmed publisher
Schiappacassa A, Maranhão P, Souza M, Panazzolo D, Nogueira Neto J, Bouskela E, et al. Acute Effects of Metformin and Vildagliptin after a Lipid-Rich Meal on Postprandial Microvascular Reactivity in Patients with Type 2 Diabetes and Obesity: A Randomized Trial. J Clin Med. 2020;9: pubmed publisher
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Maayah Z, Takahara S, Alam A, Ferdaoussi M, Sutendra G, El Kadi A, et al. Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling. BMC Cancer. 2020;20:751 pubmed publisher
Piotrowicz Z, Chalimoniuk M, Płoszczyca K, Czuba M, Langfort J. Exercise-Induced Elevated BDNF Level Does Not Prevent Cognitive Impairment Due to Acute Exposure to Moderate Hypoxia in Well-Trained Athletes. Int J Mol Sci. 2020;21: pubmed publisher
Kim M, Kim H, Yu S, Lee B, Jeon S, Lee J, et al. Combination of Red Clover and Hops Extract Improved Menopause Symptoms in an Ovariectomized Rat Model. Evid Based Complement Alternat Med. 2020;2020:7941391 pubmed publisher
Jung J, Noh T, Jo S, Kim S, Song Y, Kim Y, et al. Guanine Deaminase in Human Epidermal Keratinocytes Contributes to Skin Pigmentation. Molecules. 2020;25: pubmed publisher
Wilson D, Howard M, Fung A, O Donoghue F, Barnes M, Lappas M, et al. Sleep-disordered breathing does not impact maternal outcomes in women with hypertensive disorders of pregnancy. PLoS ONE. 2020;15:e0232287 pubmed publisher
Selvaraju V, Ayine P, Fadamiro M, Babu J, Brown M, Geetha T. Urinary Biomarkers of Inflammation and Oxidative Stress Are Elevated in Obese Children and Correlate with a Marker of Endothelial Dysfunction. Oxid Med Cell Longev. 2019;2019:9604740 pubmed publisher
Castellazzi M, Lamberti G, Resi M, Baldi E, Caniatti L, Galante G, et al. Increased Levels of Endothelin-1 in Cerebrospinal Fluid Are a Marker of Poor Visual Recovery after Optic Neuritis in Multiple Sclerosis Patients. Dis Markers. 2019;2019:9320791 pubmed publisher
Niewiarowska Sendo A, Kozik A, Guevara Lora I. Influence of bradykinin B2 receptor and dopamine D2 receptor on the oxidative stress, inflammatory response, and apoptotic process in human endothelial cells. PLoS ONE. 2018;13:e0206443 pubmed publisher
Wu C, Su M, Wu Y, Hwang J, Lin L. Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients. J Clin Med. 2018;7: pubmed publisher
Kong Y, Gao Y, Lan D, Zhang Y, Zhan R, Liu M, et al. Trans-repression of NFκB pathway mediated by PPARγ improves vascular endothelium insulin resistance. J Cell Mol Med. 2019;23:216-226 pubmed publisher
Chebib N, Archer F, Bobet Erny A, Leroux C, Cottin V. Dysregulation of the endothelin pathway in lymphangioleiomyomatosis with no direct effect on cell proliferation and migration. Sci Rep. 2018;8:14698 pubmed publisher
Houde M, Schwertani A, Touil H, Desbiens L, Sarrhini O, Lecomte R, et al. Mouse Mast Cell Protease 4 Deletion Protects Heart Function and Survival After Permanent Myocardial Infarction. Front Pharmacol. 2018;9:868 pubmed publisher
Roato I, Belisario D, Compagno M, Verderio L, Sighinolfi A, Mussano F, et al. Adipose-Derived Stromal Vascular Fraction/Xenohybrid Bone Scaffold: An Alternative Source for Bone Regeneration. Stem Cells Int. 2018;2018:4126379 pubmed publisher
Li Y, Sheu W, Lee W, Wang J, Fu C, Liang K, et al. Synergistic effect of renalase and chronic kidney disease on endothelin-1 in patients with coronary artery disease ? a cross-sectional study. Sci Rep. 2018;8:7378 pubmed publisher
Caldeira Dias M, Luizon M, Deffune E, Tanus Santos J, Freire P, Carvalho R, et al. Preeclamptic plasma stimulates the expression of miRNAs, leading to a decrease in endothelin-1 production in endothelial cells. Pregnancy Hypertens. 2018;12:75-81 pubmed publisher
Mayyas F, Jaradat R, Alzoubi K. Cardiac effects of fish oil in a rat model of streptozotocin-induced diabetes. Nutr Metab Cardiovasc Dis. 2018;28:592-599 pubmed publisher
Mancini S, Boyd D, Katwan O, Strembitska A, Almabrouk T, Kennedy S, et al. Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms. Sci Rep. 2018;8:5276 pubmed publisher
D Souza A, Chevillet J, Ghanouni P, Yan X, Tewari M, Gambhir S. Tumor characterization by ultrasound-release of multiple protein and microRNA biomarkers, preclinical and clinical evidence. PLoS ONE. 2018;13:e0194268 pubmed publisher
McKay D, Eliasziw M, Chen C, Blumberg J. A Pecan-Rich Diet Improves Cardiometabolic Risk Factors in Overweight and Obese Adults: A Randomized Controlled Trial. Nutrients. 2018;10: pubmed publisher
Ruediger C, John B, Kumar S, Lim H, Rangnekar G, Roberts Thomson K, et al. Influence of ethnic background on left atrial markers of inflammation, endothelial function and tissue remodelling. Indian Pacing Electrophysiol J. 2018;18:1-5 pubmed publisher
Giles L, Tebbutt S, CARLSTEN C, Koehle M. The effect of low and high-intensity cycling in diesel exhaust on flow-mediated dilation, circulating NOx, endothelin-1 and blood pressure. PLoS ONE. 2018;13:e0192419 pubmed publisher
Guo X, Chen H, Han L, Haulon S, Kassab G. Chronic ETA antagonist reverses hypertension and impairment of structure and function of peripheral small arteries in aortic stiffening. Sci Rep. 2018;8:3076 pubmed publisher
Allam H, Masri A. The Potential Therapeutic Role of Peroxisome ProliferatorActivated Receptors Agonist in Preeclamptic Pregnant Rats. J Coll Physicians Surg Pak. 2018;28:31-35 pubmed publisher
Russignan A, Spina C, Tamassia N, Cassaro A, Rigo A, Bagnato A, et al. Endothelin-1 receptor blockade as new possible therapeutic approach in multiple myeloma. Br J Haematol. 2017;178:781-793 pubmed publisher
Khalid W, Varghese S, Sankari M, Jayakumar N. Comparison of Serum Levels of Endothelin-1 in Chronic Periodontitis Patients Before and After Treatment. J Clin Diagn Res. 2017;11:ZC78-ZC81 pubmed publisher
Treweeke A, Hall J, Lambie S, Leslie S, Megson I, MacRury S. Preliminary study of hypoxia-related cardiovascular mediator-markers in patients with end-stage renal disease with and without diabetes and the effects of haemodialysis. PLoS ONE. 2017;12:e0178171 pubmed publisher
Koehl B, Nivoit P, El Nemer W, Lenoir O, Hermand P, Pereira C, et al. The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease. Haematologica. 2017;102:1161-1172 pubmed publisher
Lin J, Chudasama N, Hayashi Y, Hawk C, Ramnauth S, Wong K, et al. Peripheral venous congestion causes time- and dose-dependent release of endothelin-1 in humans. Physiol Rep. 2017;5: pubmed publisher
Wang C, Chang D, Chen M, Zhao M. HMGB1 contributes to glomerular endothelial cell injury in ANCA-associated vasculitis through enhancing endothelium-neutrophil interactions. J Cell Mol Med. 2017;21:1351-1360 pubmed publisher
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Mei M, Cheng G, Sun B, Yang L, Wang H, Sun J, et al. EDN1 Gene Variant is Associated with Neonatal Persistent Pulmonary Hypertension. Sci Rep. 2016;6:29877 pubmed publisher
Wu S, Yang D, Pan L, Shan J, Li H, Wei H, et al. Chemical constituents and sources of ambient particulate air pollution and biomarkers of endothelial function in a panel of healthy adults in Beijing, China. Sci Total Environ. 2016;560-561:141-9 pubmed publisher
Michaels D, Leibowitz J, Azaiza M, Shil P, Shama S, Kutish G, et al. Cellular Microbiology of Mycoplasma canis. Infect Immun. 2016;84:1785-1795 pubmed publisher
Hou H, Yuan N, Guo Q, Sun T, Li C, Liu J, et al. Citreoviridin Enhances Atherogenesis in Hypercholesterolemic ApoE-Deficient Mice via Upregulating Inflammation and Endothelial Dysfunction. PLoS ONE. 2015;10:e0125956 pubmed publisher
Wang J, Wang D, Wang H, Wang Z, Wen Y, Sun C, et al. Tumor necrosis factor-alpha-induced reduction of glomerular filtration rate in rats with fulminant hepatic failure. Lab Invest. 2014;94:740-51 pubmed publisher
Liu B, Wu Y, Zhou Y, Peng D. Endothelin A receptor antagonism enhances inhibitory effects of anti-ganglioside GD2 monoclonal antibody on invasiveness and viability of human osteosarcoma cells. PLoS ONE. 2014;9:e93576 pubmed publisher
Pallis F, Conran N, Fertrin K, Olalla Saad S, Costa F, Franco Penteado C. Hydroxycarbamide reduces eosinophil adhesion and degranulation in sickle cell anaemia patients. Br J Haematol. 2014;164:286-95 pubmed publisher
Liu B, ESCALERA J, Balakrishna S, Fan L, Caceres A, Robinson E, et al. TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis. FASEB J. 2013;27:3549-63 pubmed publisher
Wang J, Wang L, Song G, Han B. The mechanism through which octreotide inhibits hepatic stellate cell activity. Mol Med Rep. 2013;7:1559-64 pubmed publisher
Sang H, Yuan N, Yao S, Li F, Wang J, Fang Y, et al. Inhibitory effect of the combination therapy of simvastatin and pinocembrin on atherosclerosis in ApoE-deficient mice. Lipids Health Dis. 2012;11:166 pubmed publisher
Sikkeland L, Dahl C, Ueland T, Andreassen A, Gude E, Edvardsen T, et al. Increased levels of inflammatory cytokines and endothelin-1 in alveolar macrophages from patients with chronic heart failure. PLoS ONE. 2012;7:e36815 pubmed publisher
Jain A, Olovsson M, Burton G, Yung H. Endothelin-1 induces endoplasmic reticulum stress by activating the PLC-IP(3) pathway: implications for placental pathophysiology in preeclampsia. Am J Pathol. 2012;180:2309-20 pubmed publisher
Rafnsson A, Bohm F, Settergren M, Gonon A, Brismar K, Pernow J. The endothelin receptor antagonist bosentan improves peripheral endothelial function in patients with type 2 diabetes mellitus and microalbuminuria: a randomised trial. Diabetologia. 2012;55:600-7 pubmed publisher
image
image 1 :
R&D Systems DET100 image 1
Multi-species Endothelin-1 ELISA Standard Curve
product information
brand :
R&D Systems
master code :
DET100
SKU :
DET100
product name :
Endothelin-1 Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
seo description :
The Endothelin-1 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies multi-species Endothelin-1 in cell culture supernates (75 ul), serum (75 ul), edta plasma (75 ul), heparin plasma (75 ul), urine (75 ul).
target :
Endothelin-1
category :
ELISAs
dilution :
ELISA
species :
Multi-Species
specificity :
Synthetic and natural Endothelin-1
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (75 uL), Serum (75 uL), EDTA Plasma (75 uL), Heparin Plasma (75 uL), Urine (75 uL)
elisaSensitivity :
0.207 pg/mL
elisaRange :
0.39 - 25 pg/mL
top caption :
Multi-species Endothelin-1 ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Endothelin-1 immunoassay is a 4.5 hour solid phase ELISA designed to measure ET-1 in cell culture supernates, serum, plasma, and urine. It contains synthetic ET-1 and antibodies raised against synthetic ET-1. This immunoassay has been shown to accurately quantitate synthetic and naturally occurring ET-1.
alt names :
ARCND3, EDN1, endothelin 1, endothelin-1, ET1, HDLCQ7, PPET1, Preproendothelin-1, QME
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.