product summary
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company name :
R&D Systems
product type :
ELISA/assay
product name :
Human CX3CL1/Fractalkine Quantikine ELISA Kit
catalog :
DCX310
quantity :
1 Kit
price :
655 USD
more info or order :
citations: 25
Reference
Hesson J, Fudge N, Grant M. Cytomegalovirus Immunity, Inflammation and Cognitive Abilities in the Elderly. Viruses. 2021;13: pubmed publisher
Ravichandran S, Grubbs G, Tang J, Lee Y, Huang C, Golding H, et al. Systemic and mucosal immune profiling in asymptomatic and symptomatic SARS-CoV-2-infected individuals reveal unlinked immune signatures. Sci Adv. 2021;7:eabi6533 pubmed publisher
Jang H, Kim M, Hong S, Lee K, Park M, Yang K, et al. Early postoperative urinary MCP-1 as a potential biomarker predicting acute rejection in living donor kidney transplantation: a prospective cohort study. Sci Rep. 2021;11:18832 pubmed publisher
Sendic S, Mansouri L, Lundberg S, Nopp A, Jacobson S, Lundahl J. B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy. PLoS ONE. 2021;16:e0248056 pubmed publisher
Helmke A, Hüsing A, Gaedcke S, Brauns N, Balzer M, Reinhardt M, et al. Peritoneal dialysate-range hypertonic glucose promotes T-cell IL-17 production that induces mesothelial inflammation. Eur J Immunol. 2021;51:354-367 pubmed publisher
Fu R, Guo H, Janga S, Choi M, Klinngam W, Edman M, et al. Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren's syndrome murine model. Sci Rep. 2020;10:1455 pubmed publisher
Mangold A, Hofbauer T, Ondracek A, Artner T, Scherz T, Speidl W, et al. Neutrophil extracellular traps and monocyte subsets at the culprit lesion site of myocardial infarction patients. Sci Rep. 2019;9:16304 pubmed publisher
Kashiwagi M, Imanishi T, Ozaki Y, Taruya A, Nishiguchi T, Katayama Y, et al. Prognostic Value of Human Peripheral Monocyte Subsets for Future Coronary Events in Patients Without Significant Coronary Artery Stenosis. Circ J. 2019;83:2250-2256 pubmed publisher
Im E, Lee C, Moon P, Rangaswamy G, Lee B, Lee J, et al. Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A. Nat Commun. 2019;10:1387 pubmed publisher
Hoffmann Vold A, Weigt S, Palchevskiy V, Volkmann E, Saggar R, Li N, et al. Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis. PLoS ONE. 2018;13:e0206545 pubmed publisher
Huang X, Zeng Y, Jiang Y, Qin Y, Luo W, Xiang S, et al. Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB. Mediators Inflamm. 2017;2017:9734837 pubmed publisher
Kulkarni M, Bowman E, Gabriel J, Amburgy T, Mayne E, Zidar D, et al. Altered Monocyte and Endothelial Cell Adhesion Molecule Expression Is Linked to Vascular Inflammation in Human Immunodeficiency Virus Infection. Open Forum Infect Dis. 2016;3:ofw224 pubmed publisher
Galgani J, Gomez C, Mizgier M, Gutierrez J, Santos J, Olmos P, et al. Assessment of the Role of Metabolic Determinants on the Relationship between Insulin Sensitivity and Secretion. PLoS ONE. 2016;11:e0168352 pubmed publisher
Boag S, Das R, Shmeleva E, Bagnall A, Egred M, Howard N, et al. T lymphocytes and fractalkine contribute to myocardial ischemia/reperfusion injury in patients. J Clin Invest. 2015;125:3063-76 pubmed publisher
Kassianos A, Wang X, Sampangi S, Afrin S, Wilkinson R, Healy H. Fractalkine-CX3CR1-dependent recruitment and retention of human CD1c+ myeloid dendritic cells by in vitro-activated proximal tubular epithelial cells. Kidney Int. 2015;87:1153-63 pubmed publisher
Ostroff R, Mehan M, Stewart A, Ayers D, Brody E, Williams S, et al. Early detection of malignant pleural mesothelioma in asbestos-exposed individuals with a noninvasive proteomics-based surveillance tool. PLoS ONE. 2012;7:e46091 pubmed publisher
Richter B, Koller L, Hohensinner P, Rychli K, Zorn G, Goliasch G, et al. Fractalkine is an independent predictor of mortality in patients with advanced heart failure. Thromb Haemost. 2012;108:1220-7 pubmed publisher
Stolla M, Pelisek J, von Brühl M, Schafer A, Barocke V, Heider P, et al. Fractalkine is expressed in early and advanced atherosclerotic lesions and supports monocyte recruitment via CX3CR1. PLoS ONE. 2012;7:e43572 pubmed publisher
Rødland E, Ueland T, Bjørnsen S, Sagen E, Dahl C, Naalsund A, et al. Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis. BMC Infect Dis. 2012;12:144 pubmed
Cox S, Sallustio F, Serino G, Loverre A, Pesce F, Gigante M, et al. Activated innate immunity and the involvement of CX3CR1-fractalkine in promoting hematuria in patients with IgA nephropathy. Kidney Int. 2012;82:548-60 pubmed publisher
Xu Y, Zeng K, Han Y, Wang L, Chen D, Xi Z, et al. Altered expression of CX3CL1 in patients with epilepsy and in a rat model. Am J Pathol. 2012;180:1950-62 pubmed publisher
Gaudin F, Nasreddine S, Donnadieu A, Emilie D, Combadiere C, Prevot S, et al. Identification of the chemokine CX3CL1 as a new regulator of malignant cell proliferation in epithelial ovarian cancer. PLoS ONE. 2011;6:e21546 pubmed publisher
Shah R, Hinkle C, Ferguson J, Mehta N, Li M, Qu L, et al. Fractalkine is a novel human adipochemokine associated with type 2 diabetes. Diabetes. 2011;60:1512-8 pubmed publisher
Matsumiya T, Ota K, Imaizumi T, Yoshida H, Kimura H, Satoh K. Characterization of synergistic induction of CX3CL1/fractalkine by TNF-alpha and IFN-gamma in vascular endothelial cells: an essential role for TNF-alpha in post-transcriptional regulation of CX3CL1. J Immunol. 2010;184:4205-14 pubmed publisher
Huang Y, Su P, Liu G, Crow M, Chaukos D, Yan H, et al. Constitutive endocytosis of the chemokine CX3CL1 prevents its degradation by cell surface metalloproteases. J Biol Chem. 2009;284:29644-53 pubmed publisher
image
image 1 :
R&D Systems DCX310 image 1
Human CX3CL1/Fractalkine ELISA Cell Culture Supernate/Saliva Standard Curve
product information
brand :
R&D Systems
master code :
DCX310
SKU :
DCX310
product name :
Human CX3CL1/Fractalkine Quantikine ELISA Kit
unit size :
1 Kit
seo description :
The Human CX3CL1/Fractalkine Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human CX3CL1/Fractalkine in cell culture supernates (100 ul), serum (100 ul), edta plasma (100 ul), heparin plasma (100 ul), saliva (50 ul), urine (50 ul), human milk (100 ul).
target :
CX3CL1/Fractalkine
category :
ELISAs
dilution :
ELISA
species :
Human
specificity :
Natural and recombinant human Fractalkine. This assay detects all forms of human Fractalkine containing the chemokine domain.
gene symbol :
CX3CL1
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (100 uL), Serum (100 uL), EDTA Plasma (100 uL), Heparin Plasma (100 uL), Saliva (50 uL), Urine (50 uL), Human Milk (100 uL)
elisaSensitivity :
0.072 ng/mL
elisaRange :
0.16 - 10 ng/mL
top caption :
Human CX3CL1/Fractalkine ELISA Cell Culture Supernate/Saliva Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human Fractalkine immunoassay is a 4.5 hour solid phase ELISA designed to measure Fractalkine in cell culture supernates, serum, plasma, saliva, urine, and human milk. It contains NS0-expressed recombinant human Fractalkine and has been shown to accurately quantitate the recombinant factor. Results obtained using natural Fractalkine showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Fractalkine.
alt names :
ABCD-3, C3Xkine, chemokine (C-X3-C motif) ligand 1, CX3C membrane-anchored chemokine, CXC3, CXC3C, FKN, fractalkine, Neurotactin, neurotactin), NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, NTTSmall-inducible cytokine D1, SCYD1C-X3-C motif chemokine 1, small inducible cytokine subfamily D (Cys-X3-Cys), member-1
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.