Human COMP Quantikine ELISA Kit | R&D Systems DCMP0 product information

product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human COMP Quantikine ELISA Kit

catalog :

DCMP0

quantity :

1 Kit

price :

655 USD

more info or order :

R&D Systems product webpage

citations: 12

Reference
Nishida Y, Hashimoto Y, Orita K, Nishino K, Kinoshita T, Iida K, et al. Longitudinal measurement of serum cartilage oligomeric matrix protein can detect the progression of cartilage degeneration in anterior cruciate ligament reconstruction patients. Asia Pac J Sports Med Arthrosc Rehabil Technol. 2024;37:27-32 pubmed publisher
Kim H, Lee H. The Effect of 13 Weeks Long-Distance Bicycle Riding on Inflammatory Response Indicators Related to Joint Cartilage and Muscle Damage. Int J Environ Res Public Health. 2022;19: pubmed publisher
Papaneophytou C, Alabajos Cea A, Viosca Herrero E, Calvis C, Costa M, Christodoulides A, et al. Associations between serum biomarkers of cartilage metabolism and serum hyaluronic acid, with risk factors, pain categories, and disease severity in knee osteoarthritis: a pilot study. BMC Musculoskelet Disord. 2022;23:195 pubmed publisher
Jhan S, Wang C, Wu K, Siu K, Ko J, Huang W, et al. Comparison of Extracorporeal Shockwave Therapy with Non-Steroid Anti-Inflammatory Drugs and Intra-Articular Hyaluronic Acid Injection for Early Osteoarthritis of the Knees. Biomedicines. 2022;10: pubmed publisher
Fu Y, Huang Y, Yang Z, Chen Y, Zheng J, Mao C, et al. Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury. Cell Res. 2021;31:773-790 pubmed publisher
Winsz Szczotka K, Kuznik Trocha K, Gruenpeter A, Wojdas M, Dąbkowska K, Olczyk K. Association of Circulating COMP and YKL-40 as Markers of Metabolic Changes of Cartilage with Adipocytokines in Juvenile Idiopathic Arthritis. Metabolites. 2020;10: pubmed publisher
Sun L, Wang Y, Wang L, Yao B, Chen T, Li Q, et al. Resolvin D1 prevents epithelial-mesenchymal transition and reduces the stemness features of hepatocellular carcinoma by inhibiting paracrine of cancer-associated fibroblast-derived COMP. J Exp Clin Cancer Res. 2019;38:170 pubmed publisher
Nfonsam V, Jecius H, Chen D, Omesiete P, Ewongwo A, Elquza E, et al. Increasing Incidence of Colon Cancer in the Young: Assessing the Tumor Biology. J Am Coll Surg. 2019;: pubmed publisher
Pérez García S, Carrión M, Villanueva Romero R, Hermida Gómez T, Fernández Moreno M, Mellado M, et al. Wnt and RUNX2 mediate cartilage breakdown by osteoarthritis synovial fibroblast-derived ADAMTS-7 and -12. J Cell Mol Med. 2019;23:3974-3983 pubmed publisher
Azukizawa M, Ito H, Hamamoto Y, Fujii T, Morita Y, Okahata A, et al. The Effects of Well-Rounded Exercise Program on Systemic Biomarkers Related to Cartilage Metabolism. Cartilage. 2019;10:451-458 pubmed publisher
López H, Habowski S, Sandrock J, Raub B, Kedia A, Bruno E, et al. Effects of dietary supplementation with a standardized aqueous extract of Terminalia chebula fruit (AyuFlex®) on joint mobility, comfort, and functional capacity in healthy overweight subjects: a randomized placebo-controlled clinical trial. BMC Complement Altern Med. 2017;17:475 pubmed publisher
Das Gupta E, Ng W, Wong S, Bhurhanudeen A, Yeap S. Correlation of serum cartilage oligomeric matrix protein (COMP) and interleukin-16 (IL-16) levels with disease severity in primary knee osteoarthritis: A pilot study in a Malaysian population. PLoS ONE. 2017;12:e0184802 pubmed publisher

image

image 1 :

Human COMP/Thrombospondin-5 ELISA Standard Curve

product information

master code :

DCMP0

SKU :

DCMP0

product name :

Human COMP Quantikine ELISA Kit

unit size :

1 Kit

description :

The Human COMP Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human COMP/Thrombospondin-5 in cell culture supernates (50 ul), cell lysates (50 ul), serum (10 ul), edta plasma (10 ul), heparin plasma (10 ul).

target :

COMP/Thrombospondin-5

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human COMP

gene symbol :

COMP

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Cell Lysates (50 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL)

elisaSensitivity :

0.036 ng/mL

elisaRange :

0.16 - 10 ng/mL

top caption :

Human COMP/Thrombospondin-5 ELISA Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human COMP immunoassay is a 4.5 hour solid phase ELISA designed to measure human COMP in cell culture supernates, cell lysates, serum, and plasma. It contains NS0-expressed recombinant human COMP and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human COMP showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring COMP.

alt names :

cartilage oligomeric matrix protein, cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia1, multiple), cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia1, multiple), EDM1, EPD1, MED, MEDMGC131819, MGC149768, PSACH, pseudoachondroplasia (epiphyseal dysplasia 1, multiple), THBS5, Thrombospondin5, Thrombospondin-5, TSP5

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.

more info or order :

R&D Systems product webpage