product summary
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company name :
R&D Systems
product type :
ELISA/assay
product name :
Human SCF Quantikine ELISA Kit
catalog :
DCK00
quantity :
1 Kit
price :
655 USD
more info or order :
citations: 25
Reference
Huang J, Chen S, Chang W, Hung W, Wu P, Wu L, et al. KITLG Promotes Glomerular Endothelial Cell Injury in Diabetic Nephropathy by an Autocrine Effect. Int J Mol Sci. 2022;23: pubmed publisher
Yuan Y, Zhou C, Yang Q, Ma S, Wang X, Guo X, et al. HIV-1 Tat protein inhibits the hematopoietic support function of human bone marrow mesenchymal stem cells. Virus Res. 2019;273:197756 pubmed publisher
Sun T, Ju M, Dai X, Dong H, Gu W, Gao Y, et al. Multilevel defects in the hematopoietic niche in essential thrombocythemia. Haematologica. 2020;105:661-673 pubmed publisher
Vermeulen M, Del Vento F, DE Michele F, Poels J, Wyns C. Development of a Cytocompatible Scaffold from Pig Immature Testicular Tissue Allowing Human Sertoli Cell Attachment, Proliferation and Functionality. Int J Mol Sci. 2018;19: pubmed publisher
Zhang Y, He L, Selimoglu Buet D, Jego C, Morabito M, Willekens C, et al. Engraftment of chronic myelomonocytic leukemia cells in immunocompromised mice supports disease dependency on cytokines. Blood Adv. 2017;1:972-979 pubmed publisher
Desbourdes L, Javary J, Charbonnier T, Ishac N, Bourgeais J, Iltis A, et al. Alteration Analysis of Bone Marrow Mesenchymal Stromal Cells from De Novo Acute Myeloid Leukemia Patients at Diagnosis. Stem Cells Dev. 2017;26:709-722 pubmed publisher
Fischer Fodor E, Mikláš R, Rišiaňová L, Cenariu M, Grosu I, Virag P, et al. Novel Palladium(II) Complexes that Influence Prominin-1/CD133 Expression and Stem Cell Factor Release in Tumor Cells. Molecules. 2017;22: pubmed publisher
Abu El Asrar A, Nawaz M, Kangave D, Mairaj Siddiquei M, Geboes K. Angiogenic and vasculogenic factors in the vitreous from patients with proliferative diabetic retinopathy. J Diabetes Res. 2013;2013:539658 pubmed publisher
Harmon C, DePrimo S, Raymond E, Cheng A, Boucher E, Douillard J, et al. Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib. J Transl Med. 2011;9:120 pubmed publisher
Lee J, Song Y, Shin J, Kwon Y, Shin M, Kim J. The change of cytokines in tear and blood after different pterygium operation. Cytokine. 2010;49:148-54 pubmed publisher
Farha S, Asosingh K, Laskowski D, Hammel J, Dweik R, Wiedemann H, et al. Effects of the menstrual cycle on lung function variables in women with asthma. Am J Respir Crit Care Med. 2009;180:304-10 pubmed publisher
Schuster C, Vaculik C, Fiala C, Meindl S, Brandt O, Imhof M, et al. HLA-DR+ leukocytes acquire CD1 antigens in embryonic and fetal human skin and contain functional antigen-presenting cells. J Exp Med. 2009;206:169-81 pubmed publisher
Westerweel P, Visseren F, Hajer G, Olijhoek J, Hoefer I, de Bree P, et al. Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy. Eur Heart J. 2008;29:2808-17 pubmed publisher
Hollins F, Kaur D, Yang W, Cruse G, Saunders R, Sutcliffe A, et al. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J Immunol. 2008;181:2772-80 pubmed
Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, et al. Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp Hematol. 2008;36:1035-46 pubmed publisher
Han Z, Ren H, Zhao H, Chi Y, Chen K, Zhou B, et al. Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF). Carcinogenesis. 2008;29:1853-61 pubmed publisher
Makowska J, Grzegorczyk J, Bienkiewicz B, Wozniak M, Kowalski M. Systemic responses after bronchial aspirin challenge in sensitive patients with asthma. J Allergy Clin Immunol. 2008;121:348-54 pubmed
Dentelli P, Rosso A, Balsamo A, Colmenares Benedetto S, Zeoli A, Pegoraro M, et al. C-KIT, by interacting with the membrane-bound ligand, recruits endothelial progenitor cells to inflamed endothelium. Blood. 2007;109:4264-71 pubmed
Hatfield K, Ryningen A, Corbascio M, Bruserud O. Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts. Int J Cancer. 2006;119:2313-21 pubmed
Drouet M, Mourcin F, Grenier N, Leroux V, Denis J, Mayol J, et al. Single administration of stem cell factor, FLT-3 ligand, megakaryocyte growth and development factor, and interleukin-3 in combination soon after irradiation prevents nonhuman primates from myelosuppression: long-term follow-up of hematopoiesis. Blood. 2004;103:878-85 pubmed
Lamming C, Augustin L, Blackstad M, Lund T, Hebbel R, Verfaillie C. Spontaneous circulation of myeloid-lymphoid-initiating cells and SCID-repopulating cells in sickle cell crisis. J Clin Invest. 2003;111:811-9 pubmed
Briard D, Brouty Boye D, Azzarone B, Jasmin C. Fibroblasts from human spleen regulate NK cell differentiation from blood CD34(+) progenitors via cell surface IL-15. J Immunol. 2002;168:4326-32 pubmed
Bovolenta C, Pilotti E, Mauri M, Turci M, Ciancianaini P, Fisicaro P, et al. Human T-cell leukemia virus type 2 induces survival and proliferation of CD34(+) TF-1 cells through activation of STAT1 and STAT5 by secretion of interferon-gamma and granulocyte macrophage-colony-stimulating factor. Blood. 2002;99:224-31 pubmed
Hartman M, Piliponsky A, Temkin V, Levi Schaffer F. Human peripheral blood eosinophils express stem cell factor. Blood. 2001;97:1086-91 pubmed
Osuga Y, Koga K, Tsutsumi O, Igarashi T, Okagaki R, Takai Y, et al. Stem cell factor (SCF) concentrations in peritoneal fluid of women with or without endometriosis. Am J Reprod Immunol. 2000;44:231-5 pubmed
image
image 1 :
R&D Systems DCK00 image 1
Human SCF/c-kit Ligand ELISA Cell Culture Supernate Standard Curve
product information
brand :
R&D Systems
master code :
DCK00
SKU :
DCK00
product name :
Human SCF Quantikine ELISA Kit
unit size :
1 Kit
seo description :
The Human SCF Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human SCF/c-kit Ligand in cell culture supernates (100 ul), serum (100 ul), edta plasma (100 ul), heparin plasma (100 ul), citrate plasma (100 ul).
target :
SCF/c-kit Ligand
category :
ELISAs
dilution :
ELISA
species :
Human
specificity :
Natural and recombinant human SCF. This assay cross-reacts 15.6% with Canine SCF, 16.1% with Feline SCF, 3.5% with Mouse SCF and 1.0% with Rat SCF.
gene symbol :
KITLG
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (100 uL), Serum (100 uL), EDTA Plasma (100 uL), Heparin Plasma (100 uL), Citrate Plasma (100 uL)
elisaSensitivity :
9 pg/mL
elisaRange :
31.20 - 2000 pg/mL
top caption :
Human SCF/c-kit Ligand ELISA Cell Culture Supernate Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human SCF Immunoassay is a 4.5 hour solid phase ELISA designed to measure SCF levels in cell culture supernates, serum, and plasma. It contains E. coli -expressed recombinant human soluble SCF (KL-1 variant) and antibodies raised against this recombinant factor. Results obtained for naturally occurring human SCF samples showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human SCF.
alt names :
c-kit Ligand, DCUA, DFNA69, DKFZp686F2250, familial progressive hyperpigmentation 2, FPH2, FPHH, KIT ligand, Kitl, KITLG, KL-1, Mast cell growth factor, MGF, MGFSHEP7, SCFStem cell factor, SFc-Kit ligand, SHEP7, SLF, steel factor
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.