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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human Chitinase 3-like 1/YKL-40 Quantikine ELISA Kit
catalog :
DC3L10
quantity :
1 Kit
price :
655 USD
citations: 40
Reference
Yamanaka K, Koma Y, Urakami S, Takahashi R, Nagamata S, Omori M, et al. YKL40/Integrin β4 Axis Induced by the Interaction between Cancer Cells and Tumor-Associated Macrophages Is Involved in the Progression of High-Grade Serous Ovarian Carcinoma. Int J Mol Sci. 2024;25: pubmed publisher
Babel J, Ko x161 uta I, Vujaklija Brajkovi x107 A, Lon x10d ar Vran x10d i x107 A, Premu x17e i x107 V, Rogi x107 D, et al. Early Fever in Allogeneic Stem Cell Transplantation: Are Presepsin and YKL-40 Valuable Diagnostic Tools?. J Clin Med. 2024;13: pubmed publisher
Kusnierova P, Revendova K, Karasova K, Zeman D, Bunganic R, Hradilek P, et al. Neurofilament heavy chain and chitinase 3-like 1 as markers for monitoring therapeutic response in multiple sclerosis. Mult Scler Relat Disord. 2024;91:105915 pubmed publisher
Ropri A, Lam T, Kalia V, Buchanan H, Bartosch A, Youth E, et al. Alzheimer's disease CSF biomarkers correlate with early pathology and alterations in neuronal and glial gene expression. medRxiv. 2024;: pubmed publisher
Shanks H, Chen K, Reiman E, Blennow K, Cummings J, Massa S, et al. p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trial. Nat Med. 2024;30:1761-1770 pubmed publisher
Babi x107 Leko M, Mihel x10d i x107 M, Jurasovi x107 J, Nikolac Perkovi x107 M, x160 pani x107 E, Sekovani x107 A, et al. Heavy Metals and Essential Metals Are Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease. Int J Mol Sci. 2022;24: pubmed publisher
Xu T, Zhang K, Zhong C, Zhu Z, Zheng X, Yang P, et al. Plasma Human Cartilage Glycoprotein-39 Is Associated With the Prognosis of Acute Ischemic Stroke. J Am Heart Assoc. 2022;11:e026263 pubmed publisher
Huss A, Abdelhak A, Mayer B, Tumani H, M xfc ller H, Althaus K, et al. Association of Serum GFAP with Functional and Neurocognitive Outcome in Sporadic Small Vessel Disease. Biomedicines. 2022;10: pubmed publisher
Vahsen B, Gray E, Candalija A, Cramb K, Scaber J, Dafinca R, et al. Human iPSC co-culture model to investigate the interaction between microglia and motor neurons. Sci Rep. 2022;12:12606 pubmed publisher
Francuzik W, Pa x17e ur K, Dalke M, D xf6 lle Bierke S, Babina M, Worm M. Serological profiling reveals hsa-miR-451a as a possible biomarker of anaphylaxis. JCI Insight. 2022;7: pubmed publisher
Komabashiri N, Suehiro F, Ishii M, Nishimura M. Efficacy of chitinase-3-like protein 1 as an in vivo bone formation predictable marker of maxillary/mandibular bone marrow stromal cells. Regen Ther. 2021;18:38-50 pubmed publisher
Ko P, Lee H, Lee M, Youn Y, Kim S, Kim J, et al. Increased plasma levels of chitinase 3-like 1 (CHI3L1) protein in patients with idiopathic normal-pressure hydrocephalus. J Neurol Sci. 2021;423:117353 pubmed publisher
Lee Y, Lee E, Yon D, Jee H, Baek H, Lee S, et al. The potential pathways underlying the association of propyl-paraben exposure with aeroallergen sensitization and EASI score using metabolomics analysis. Sci Rep. 2021;11:3772 pubmed publisher
Robinson T, Abdelhak A, Bose T, Meinl E, Otto M, Zettl U, et al. Cerebrospinal Fluid Biomarkers in Relation to MRZ Reaction Status in Primary Progressive Multiple Sclerosis. Cells. 2020;9: pubmed publisher
Kwon Y, Kim J, Ha E, Jee H, Baek H, Han M, et al. Serum YKL-40 Levels Are Associated with the Atherogenic Index of Plasma in Children. Mediators Inflamm. 2020;2020:8713908 pubmed publisher
Gomez Llorente M, Martínez Cañavate A, Chueca N, Rico M, Romero R, Anguita Ruiz A, et al. A Multi-Omics Approach Reveals New Signatures in Obese Allergic Asthmatic Children. Biomedicines. 2020;8: pubmed publisher
Ye G, Xie Z, Zeng H, Wang P, Li J, Zheng G, et al. Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis. Cell Death Dis. 2020;11:775 pubmed publisher
Teitsdottir U, Jonsdottir M, Lund S, Darreh Shori T, Snaedal J, Petersen P. Association of glial and neuronal degeneration markers with Alzheimer's disease cerebrospinal fluid profile and cognitive functions. Alzheimers Res Ther. 2020;12:92 pubmed publisher
Shirai T, Hirai K, Gon Y, Maruoka S, Mizumura K, Hikichi M, et al. Combined assessment of serum eosinophil-derived neurotoxin and YKL-40 may identify Asthma-COPD overlap. Allergol Int. 2021;70:136-139 pubmed publisher
Kusnierova P, Zeman D, Hradilek P, Zapletalova O, Stejskal D. Determination of chitinase 3-like 1 in cerebrospinal fluid in multiple sclerosis and other neurological diseases. PLoS ONE. 2020;15:e0233519 pubmed publisher
Hoste E, Vaara S, De Loor J, Haapio M, Nuytinck L, Demeyere K, et al. Urinary cell cycle arrest biomarkers and chitinase 3-like protein 1 (CHI3L1) to detect acute kidney injury in the critically ill: a post hoc laboratory analysis on the FINNAKI cohort. Crit Care. 2020;24:144 pubmed publisher
Whitwell H, Worthington J, Blyuss O, Gentry Maharaj A, Ryan A, Gunu R, et al. Improved early detection of ovarian cancer using longitudinal multimarker models. Br J Cancer. 2020;122:847-856 pubmed publisher
Palmqvist S, Insel P, Stomrud E, Janelidze S, Zetterberg H, Brix B, et al. Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease. EMBO Mol Med. 2019;11:e11170 pubmed publisher
Lowes H, Pyle A, Duddy M, Hudson G. Cell-free mitochondrial DNA in progressive multiple sclerosis. Mitochondrion. 2019;46:307-312 pubmed publisher
Olsson M, Ärlig J, Hedner J, Blennow K, Zetterberg H. Sleep deprivation and cerebrospinal fluid biomarkers for Alzheimer's disease. Sleep. 2018;41: pubmed publisher
Jensen C, Portelius E, Høgh P, Wermuth L, Blennow K, Zetterberg H, et al. Effect of physical exercise on markers of neuronal dysfunction in cerebrospinal fluid in patients with Alzheimer's disease. Alzheimers Dement (N Y). 2017;3:284-290 pubmed publisher
Pikwer A, Castegren M, Namdar S, Blennow K, Zetterberg H, Mattsson N. Effects of surgery and propofol-remifentanil total intravenous anesthesia on cerebrospinal fluid biomarkers of inflammation, Alzheimer's disease, and neuronal injury in humans: a cohort study. J Neuroinflammation. 2017;14:193 pubmed publisher
Salomon J, Matusiak Ł, Nowicka Suszko D, Szepietowski J. Chitinase-3-Like Protein 1 (YKL-40) Is a New Biomarker of Inflammation in Psoriasis. Mediators Inflamm. 2017;2017:9538451 pubmed publisher
Salomon J, Matusiak Å, Nowicka Suszko D, Szepietowski J. Chitinase-3-Like Protein 1 (YKL-40) Reflects the Severity of Symptoms in Atopic Dermatitis. J Immunol Res. 2017;2017:5746031 pubmed publisher
Jennum P, Østergaard Pedersen L, Czarna Bahl J, Modvig S, Fog K, Holm A, et al. Cerebrospinal Fluid Biomarkers of Neurodegeneration Are Decreased or Normal in Narcolepsy. Sleep. 2017;40: pubmed publisher
Langley S, Willeit K, Didangelos A, Matic L, Skroblin P, Barallobre Barreiro J, et al. Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques. J Clin Invest. 2017;127:1546-1560 pubmed publisher
De Loor J, Herck I, Francois K, Van Wesemael A, Nuytinck L, Meyer E, et al. Diagnosis of cardiac surgery-associated acute kidney injury: differential roles of creatinine, chitinase 3-like protein 1 and neutrophil gelatinase-associated lipocalin: a prospective cohort study. Ann Intensive Care. 2017;7:24 pubmed publisher
Johansson V, Jakobsson J, Fortgang R, Zetterberg H, Blennow K, Cannon T, et al. Cerebrospinal fluid microglia and neurodegenerative markers in twins concordant and discordant for psychotic disorders. Eur Arch Psychiatry Clin Neurosci. 2017;267:391-402 pubmed publisher
Feaver R, Cole B, Lawson M, Hoang S, Marukian S, Blackman B, et al. Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis. JCI Insight. 2016;1:e90954 pubmed publisher
Vasquez M, Hu C, Roe D, Chen Z, Halonen M, Guerra S. Least absolute shrinkage and selection operator type methods for the identification of serum biomarkers of overweight and obesity: simulation and application. BMC Med Res Methodol. 2016;16:154 pubmed
Eyking A, Reis H, Frank M, Gerken G, Schmid K, Cario E. MiR-205 and MiR-373 Are Associated with Aggressive Human Mucinous Colorectal Cancer. PLoS ONE. 2016;11:e0156871 pubmed publisher
Fantino E, Gangell C, Hartl D, Sly P. Airway, but not serum or urinary, levels of YKL-40 reflect inflammation in early cystic fibrosis lung disease. BMC Pulm Med. 2014;14:28 pubmed publisher
Yan C, Ding X, Wu L, Yu M, Qu P, Du H. Stat3 downstream gene product chitinase 3-like 1 is a potential biomarker of inflammation-induced lung cancer in multiple mouse lung tumor models and humans. PLoS ONE. 2013;8:e61984 pubmed publisher
Kim H, Jun C, Lee K, Cho J, Jeong E, Yang S, et al. Levels of YKL-40 in pleural effusions and blood from patients with pulmonary or pleural disease. Cytokine. 2012;58:336-43 pubmed publisher
Hector A, Kormann M, Mack I, Latzin P, Casaulta C, Kieninger E, et al. The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease. PLoS ONE. 2011;6:e24399 pubmed publisher
product information
master code :
DC3L10
SKU :
DC3L10
product name :
Human Chitinase 3-like 1/YKL-40 Quantikine ELISA Kit
unit size :
1 Kit
description :
The Human Chitinase 3-like 1/YKL-40 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human Chitinase 3-like 1/YKL-40 in cell culture supernates (50 ul), serum (10 ul), edta plasma (10 ul), heparin plasma (10 ul), urine (50 ul).
target :
Chitinase 3-like 1/YKL-40
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human CHI3L1
gene symbol :
CHI3L1
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Urine (50 uL)
elisaSensitivity :
8.15 pg/mL
elisaRange :
62.50 - 4000 pg/mL
top caption :
Human Chitinase 3-like 1 ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human CHI3L1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure CHI3L1 in cell culture supernates, serum, plasma, and urine. It contains NS0-expressed recombinant human CHI3L1 and antibodies raised against recombinant human CHI3L1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural CHI3L1 showed dose response curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human CHI3L1.
alt names :
AW208766, Brp39, Chi3l1, Chitinase 3 like 1, gp39, HCgp39, YKL-40
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.