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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Total BDNF Quantikine ELISA Kit
catalog :
DBNT00
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 49
Reference
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Drexler R, Drinnenberg A, Gavish A, Yalçın B, Shamardani K, Rogers A, et al. Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling. bioRxiv. 2024;: pubmed publisher
Salamanca Fern xe1 ndez E, Esp xed n Moreno L, Olivas Mart xed nez A, P xe9 rez Cantero A, Mart xed n Rodr xed guez J, Poyatos R, et al. Associations between Urinary Phthalate Metabolites with BDNF and Behavioral Function among European Children from Five HBM4EU Aligned Studies. Toxics. 2024;12: pubmed publisher
Liang C, Yen C, Wang H, Tsai Y, Chye C, Wang K. Intramuscular Pulsed Radiofrequency Upregulates BNDF-TrKB Expression in the Spinal Cord in Rats as an Alternative Treatment for Complicated Pain. Int J Mol Sci. 2024;25: pubmed publisher
de Souza V, Medeiros L, Stein D, de Oliveira C, Medeiros H, Dussan Sarria J, et al. Transcranial direct current stimulation is more effective than pregabalin in controlling nociceptive and anxiety-like behaviors in a rat fibromyalgia-like model. Scand J Pain. 2024;24: pubmed publisher
Kang D, Koh S, Kim T, Bressel E, Kim D. Circuit Training Improves the Levels of β-Amyloid and Brain-Derived Neurotrophic Factor Related to Cognitive Impairment Risk Factors in Obese Elderly Korean Women. J Clin Med. 2024;13: pubmed publisher
Driskill C, Childs J, Phensy A, Rodriguez S, O Brien J, Lindquist K, et al. Vagus nerve stimulation (VNS) modulates synaptic plasticity in the rat infralimbic cortex via Trk-B receptor activation to reduce drug-seeking. bioRxiv. 2024;: pubmed publisher
Lin T, Tsai Y, Chen Y, Young T, Wu C, Chiang Y, et al. Brain-derived neurotrophic factor contributes to neurogenesis after intracerebral hemorrhage: a rodent model and human study. Front Cell Neurosci. 2023;17:1170251 pubmed publisher
Moon Y, Lee E, Lee S, Son G, Byeon H, Shin H, et al. Changes in cortisol awakening responses (CAR) in menopausal women through short-term marine healing retreat program with specific factors affecting each CAR index. PLoS ONE. 2023;18:e0284627 pubmed publisher
Chroboczek M, Kujach S, x141 uszczyk M, Soya H, Laskowski R. Exercise-Induced Elevated BDNF Concentration Seems to Prevent Cognitive Impairment after Acute Exposure to Moderate Normobaric Hypoxia among Young Men. Int J Environ Res Public Health. 2023;20: pubmed publisher
Formolo D, Lee T, Yu J, Lin K, Chen G, Kranz G, et al. Increasing Adiponectin Signaling by Sub-Chronic AdipoRon Treatment Elicits Antidepressant- and Anxiolytic-Like Effects Independent of Changes in Hippocampal Plasticity. Biomedicines. 2023;11: pubmed publisher
Al Omran A, Watanabe S, Hong E, Skinner S, Zhang M, Zhang J, et al. Dihydromyricetin ameliorates social isolation-induced anxiety by modulating mitochondrial function, antioxidant enzymes, and BDNF. Neurobiol Stress. 2022;21:100499 pubmed publisher
Takamiya S, Kawabori M, Yamazaki K, Yamaguchi S, Tanimori A, Yamamoto K, et al. Intravenous transplantation of amnion-derived mesenchymal stem cells promotes functional recovery and alleviates intestinal dysfunction after spinal cord injury. PLoS ONE. 2022;17:e0270606 pubmed publisher
Wu J, Yang S, Ho Y, Chen C, Tasi B, Lee M, et al. The Functional Vision Restorative Effect of Crocin via the BDNF-TrkB Pathway: An In Vivo Study. Nutrients. 2022;14: pubmed publisher
Jung S, Kim Y, Park W, Ahn S, Sung D, Sung S, et al. Thrombin Preconditioning Improves the Therapeutic Efficacy of Mesenchymal Stem Cells in Severe Intraventricular Hemorrhage Induced Neonatal Rats. Int J Mol Sci. 2022;23: pubmed publisher
Rodr xed guez Carrillo A, Mustieles V, D Cruz S, Legoff L, Gil F, Olmedo P, et al. Exploring the relationship between metal exposure, BDNF, and behavior in adolescent males. Int J Hyg Environ Health. 2022;239:113877 pubmed publisher
Crombie K, Sartin Tarm A, Sellnow K, Ahrenholtz R, Lee S, Matalamaki M, et al. Exercise-induced increases in Anandamide and BDNF during extinction consolidation contribute to reduced threat following reinstatement: Preliminary evidence from a randomized controlled trial. Psychoneuroendocrinology. 2021;132:105355 pubmed publisher
Li R, Ma C, Xiong Y, Zhao H, Yang Y, Xue L, et al. An Antagonistic Peptide of Gpr1 Ameliorates LPS-Induced Depression through the Hypothalamic-Pituitary-Ovarian Axis. Biomolecules. 2021;11: pubmed publisher
Sultan N, Amin L, Zaher A, Grawish M, Scheven B. Dental pulp stem cells stimulate neuronal differentiation of PC12 cells. Neural Regen Res. 2021;16:1821-1828 pubmed publisher
Chai G, Liu S, Yang H, Chen X. Quercetin protects against diabetic retinopathy in rats by inducing heme oxygenase-1 expression. Neural Regen Res. 2021;16:1344-1350 pubmed publisher
Kartalou G, Salgueiro Pereira A, Endres T, Lesnikova A, Casarotto P, Pousinha P, et al. Anti-Inflammatory Treatment with FTY720 Starting after Onset of Symptoms Reverses Synaptic Deficits in an AD Mouse Model. Int J Mol Sci. 2020;21: pubmed publisher
Zilkha Falb R, Rachutin Zalogin T, Cleaver L, Gurevich M, Achiron A. RAM-589.555 favors neuroprotective and anti-inflammatory profile of CNS-resident glial cells in acute relapse EAE affected mice. J Neuroinflammation. 2020;17:313 pubmed publisher
Sanabria Mazo J, Montero Marín J, Feliu Soler A, Gasión V, Navarro Gil M, Morillo Sarto H, et al. Mindfulness-Based Program Plus Amygdala and Insula Retraining (MAIR) for the Treatment of Women with Fibromyalgia: A Pilot Randomized Controlled Trial. J Clin Med. 2020;9: pubmed publisher
Pinazo Dur xe1 n M, Garc xed a Medina J, Bolar xed n J, Sanz Gonz xe1 lez S, Valero Velló M, Abell xe1 n Abenza J, et al. Computational Analysis of Clinical and Molecular Markers and New Theranostic Possibilities in Primary Open-Angle Glaucoma. J Clin Med. 2020;9: pubmed publisher
Williams R, Cooper S, Dring K, Hatch L, Morris J, Sunderland C, et al. Effect of football activity and physical fitness on information processing, inhibitory control and working memory in adolescents. BMC Public Health. 2020;20:1398 pubmed publisher
Stevenson W, Hase Y, Wilson E, Hollins A, Hase M, Ennaceur A, et al. Long-term effects of experimental carotid stenosis on hippocampal infarct pathology, neurons and glia and amelioration by environmental enrichment. Brain Res Bull. 2020;163:72-83 pubmed publisher
Kim T, Park S, Park J, Park H. Infusion of Plasma from Exercised Mice Ameliorates Cognitive Dysfunction by Increasing Hippocampal Neuroplasticity and Mitochondrial Functions in 3xTg-AD Mice. Int J Mol Sci. 2020;21: pubmed publisher
Geng Y, Chen Y, Sun W, Gu Y, Zhang Y, Li M, et al. Electroacupuncture Ameliorates Cerebral I/R-Induced Inflammation through DOR-BDNF/TrkB Pathway. Evid Based Complement Alternat Med. 2020;2020:3495836 pubmed publisher
Kim J, Jeong B, Jang S, Yun J, Jung M, Kang K, et al. Alpha-Lipoic Acid Ameliorates Radiation-Induced Salivary Gland Injury by Preserving Parasympathetic Innervation in Rats. Int J Mol Sci. 2020;21: pubmed publisher
Gueniot L, Lepere V, de Medeiros G, Danckaert A, Flamant P, Le Dudal M, et al. Muscle Injury Induces Postoperative Cognitive Dysfunction. Sci Rep. 2020;10:2768 pubmed publisher
Kubica J, Szymura J, Domagalik A, Golda S, Więcek M, Fafrowicz M, et al. Systematic Balance Exercises Influence Cortical Activation and Serum BDNF Levels in Older Adults. J Clin Med. 2019;8: pubmed publisher
Tian B, Yang C, Wang J, Hou X, Zhao S, Li Y, et al. Peripheral blood brain-derived neurotrophic factor level and tyrosine kinase B expression on T lymphocytes in systemic lupus erythematosus: Implications for systemic involvement. Cytokine. 2019;123:154764 pubmed publisher
Martín Martín Y, Fernández García L, Sanchez Rebato M, Marí Buyé N, Rojo F, Pérez Rigueiro J, et al. Evaluation of Neurosecretome from Mesenchymal Stem Cells Encapsulated in Silk Fibroin Hydrogels. Sci Rep. 2019;9:8801 pubmed publisher
Canteiro P, Antero D, Tramontin N, Simon K, Mendes C, Anastácio Borges Correa M, et al. Insulin treatment protects the brain against neuroinflammation by reducing cerebral cytokines and modulating mitochondrial function. Brain Res Bull. 2019;149:120-128 pubmed publisher
Danesi C, Achuta V, Corcoran P, Peteri U, Turconi G, Matsui N, et al. Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein. Stem Cell Reports. 2018;11:1449-1461 pubmed publisher
Kin K, Yasuhara T, Kameda M, Tomita Y, Umakoshi M, Kuwahara K, et al. Cell encapsulation enhances antidepressant effect of the mesenchymal stem cells and counteracts depressive-like behavior of treatment-resistant depressed rats. Mol Psychiatry. 2018;: pubmed publisher
Saitoh K, Furihata R, Kaneko Y, Suzuki M, Takahashi S, Uchiyama M. Association of serum BDNF levels and the BDNF Val66Met polymorphism with the sleep pattern in healthy young adults. PLoS ONE. 2018;13:e0199765 pubmed publisher
Tao Y, Piao S, Jin Y, Jin J, Zheng H, Zhao H, et al. Expression of brain-derived neurotrophic factor in kidneys from normal and cyclosporine-treated rats. BMC Nephrol. 2018;19:63 pubmed publisher
Brondino N, Fusar Poli L, Rocchetti M, Bertoglio F, Bloise N, Visai L, et al. BDNF levels are associated with autistic traits in the general population. Psychoneuroendocrinology. 2018;89:131-133 pubmed publisher
Kim J, Kim D. Aquarobic exercises improve the serum blood irisin and brain-derived neurotrophic factor levels in elderly women. Exp Gerontol. 2018;104:60-65 pubmed publisher
Byiers B, Barney C, Ehrhardt M, Panoskaltsis Mortari A, Feyma T, Beisang A, et al. Initial Observations of Salivary Brain-Derived Neurotrophic Factor Levels in Rett Syndrome. Pediatr Neurol. 2018;80:88-89 pubmed publisher
Yin C, Qi X. Pregnancy promotes pituitary tumors by increasing the rate of the cell cycle. Oncol Lett. 2017;14:4873-4877 pubmed publisher
Nomura T, Musial T, Marshall J, Zhu Y, Remmers C, Xu J, et al. Delayed Maturation of Fast-Spiking Interneurons Is Rectified by Activation of the TrkB Receptor in the Mouse Model of Fragile X Syndrome. J Neurosci. 2017;37:11298-11310 pubmed publisher
Stefani M, Modkovski R, Hansel G, Zimmer E, Kopczynski A, Muller A, et al. Elevated glutamate and lactate predict brain death after severe head trauma. Ann Clin Transl Neurol. 2017;4:392-402 pubmed publisher
Sungur A, Jochner M, Harb H, Kılıç A, Garn H, Schwarting R, et al. Aberrant cognitive phenotypes and altered hippocampal BDNF expression related to epigenetic modifications in mice lacking the post-synaptic scaffolding protein SHANK1: Implications for autism spectrum disorder. Hippocampus. 2017;27:906-919 pubmed publisher
Marwarha G, Claycombe Larson K, Schommer J, Ghribi O. Maternal low-protein diet decreases brain-derived neurotrophic factor expression in the brains of the neonatal rat offspring. J Nutr Biochem. 2017;45:54-66 pubmed publisher
Saliba S, Vieira E, Santos R, Candelario Jalil E, Fiebich B, Vieira L, et al. Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid. J Neuroinflammation. 2017;14:25 pubmed publisher
Guo J, Deng H, Bo X, Yang X. Involvement of BDNF/TrkB and ERK/CREB axes in nitroglycerin-induced rat migraine and effects of estrogen on these signals in the migraine. Biol Open. 2017;6:8-16 pubmed publisher
product information
master code :
DBNT00
SKU :
DBNT00
product name :
Total BDNF Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Total BDNF Quantikine ELISA Kit from R&D Systems quantifies human, mouse, rat, porcine, canine BDNF in cell culture supernates (50 ul), tissue lysates (50 ul), serum (10 ul), edta plasma (50 ul), platelet-poor edta plasma (10 ul), heparin plasma (50 ul), platelet-poor heparin plasma (10 ul), urine (50 ul), human milk (50 ul).
target :
BDNF
category :
ELISAs
species :
Human, Mouse, Rat, Porcine, Canine
specificity :
Natural and recombinant free, trk-bound, pro-, and mature BDNF.
gene symbol :
BDNF
assay length :
3.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Tissue Lysates (50 uL), Serum (10 uL), EDTA Plasma (50 uL), Platelet-poor EDTA Plasma (10 uL), Heparin Plasma (50 uL), Platelet-poor Heparin Plasma (10 uL), Urine (50 uL), Human Milk (50 uL)
elisaSensitivity :
1.35 pg/mL
elisaRange :
15.60 - 1000 pg/mL
top caption :
Human/Mouse/Rat/Porcine/Canine Total BDNF ELISA Standard Curve
applications :
ELISA
extended description :
Detects free and Trk-bound BDNF
USD :
655 USD
product details :
The Quantikine Total BDNF Immunoassay is a 3.5 hour solid phase ELISA designed to measure BDNF in cell culture supernates, tissue lysates, serum, plasma, urine, and human milk. It contains recombinant human BDNF expressed in Sf 21 cells and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant BDNF accurately. Results obtained measuring natural BDNF showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural BDNF.
alt names :
abrineurin, ANON2, brain-derived neurotrophic factor, BULN2, MGC34632, neurotrophin
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.