This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human BAFF/BLyS/TNFSF13B Quantikine ELISA Kit
catalog :
DBLYS0B
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 67
Reference
Lin J, Deng W, Liao J, Ke D, Cui L, Zhong H, et al. BAFF deficiency aggravated optic nerve crush-induced retinal ganglion cells damage by regulating apoptosis and neuroinflammation via NF-κB-IκBα signaling. Int Immunopharmacol. 2024;126:111287 pubmed publisher
Rahm xe9 Z, Franco C, Cruciani C, Pettorossi F, Zaramella A, Realdon S, et al. Characterization of Serum Cytokine Profiles of Patients with Active Lupus Nephritis. Int J Mol Sci. 2023;24: pubmed publisher
Gyllemark P, Sj xf6 wall J, Forsberg P, Ernerudh J, Henningsson A. Intrathecal Th17-driven inflammation is associated with prolonged post-treatment convalescence for patients with Lyme neuroborreliosis. Sci Rep. 2023;13:9722 pubmed publisher
Lievin R, Hendel Chavez H, Bald xe9 A, Lancar R, Algarte G xe9 nin M, Krzysiek R, et al. Increased Production of B-Cell Activating Cytokines and Altered Peripheral B-Cell Subset Distribution during HIV-Related Classical Hodgkin Lymphoma. Cancers (Basel). 2021;14: pubmed publisher
Alturaiki W, Mubarak A, Mir S, Afridi A, Premanathan M, Mickymaray S, et al. Plasma levels of BAFF and APRIL are elevated in patients with asthma in Saudi Arabia. Saudi J Biol Sci. 2021;28:7455-7459 pubmed publisher
Wang X, Huang J, Zhang A, Fang C, Ma Q, Jiang P. Altered expression profile of BAFF receptors on peripheral blood B lymphocytes in Graves' disease. BMC Endocr Disord. 2021;21:88 pubmed publisher
Sendic S, Mansouri L, Lundberg S, Nopp A, Jacobson S, Lundahl J. B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy. PLoS ONE. 2021;16:e0248056 pubmed publisher
Crake R, Strother M, Phillips E, Doogue M, Zhang M, Frampton C, et al. Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study. Sci Rep. 2021;11:5648 pubmed publisher
Rönnberg C, Lugaajju A, Nyman A, Hammar U, Bottai M, Lautenbach M, et al. A longitudinal study of plasma BAFF levels in mothers and their infants in Uganda, and correlations with subsets of B cells. PLoS ONE. 2021;16:e0245431 pubmed publisher
Robinson T, Abdelhak A, Bose T, Meinl E, Otto M, Zettl U, et al. Cerebrospinal Fluid Biomarkers in Relation to MRZ Reaction Status in Primary Progressive Multiple Sclerosis. Cells. 2020;9: pubmed publisher
Barman M, Rabe H, Hesselmar B, Johansen S, Sandberg A, Wold A. Cord Blood Levels of EPA, a Marker of Fish Intake, Correlate with Infants' T- and B-Lymphocyte Phenotypes and Risk for Allergic Disease. Nutrients. 2020;12: pubmed publisher
Liba Z, Vaskova M, Zamecnik J, Kayserová J, Nohejlova H, Ebel M, et al. An immunotherapy effect analysis in Rasmussen encephalitis. BMC Neurol. 2020;20:359 pubmed publisher
Muema D, Akilimali N, Ndumnego O, Rasehlo S, Durgiah R, Ojwach D, et al. Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection. BMC Med. 2020;18:81 pubmed publisher
Piuri G, Basello K, Rossi G, Soldavini C, Duiella S, Privitera G, et al. Methylglyoxal, Glycated Albumin, PAF, and TNF-α: Possible Inflammatory and Metabolic Biomarkers for Management of Gestational Diabetes. Nutrients. 2020;12: pubmed publisher
Irure Ventura J, San Segundo D, Rodrigo E, Merino D, Belmar Vega L, Ruiz San Millán J, et al. High Pretransplant BAFF Levels and B-cell Subset Polarized towards a Memory Phenotype as Predictive Biomarkers for Antibody-Mediated Rejection. Int J Mol Sci. 2020;21: pubmed publisher
Brinkhoff A, Zeng Y, Sieberichs A, Dolff S, Shilei X, Sun M, et al. B-cell dynamics during experimental endotoxemia in humans. Biosci Rep. 2019;39: pubmed publisher
Lagou V, Garcia Perez J, Smets I, Van Horebeek L, Vandebergh M, Chen L, et al. Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators. Cell Rep. 2018;25:798-810.e6 pubmed publisher
Wilhelmson A, Lantero Rodriguez M, Stubelius A, Fogelstrand P, Johansson I, Buechler M, et al. Testosterone is an endogenous regulator of BAFF and splenic B cell number. Nat Commun. 2018;9:2067 pubmed publisher
James K, Chipeta C, Parker A, Harding S, Cockell S, Gillespie C, et al. B-cell activity markers are associated with different disease activity domains in primary Sjögren's syndrome. Rheumatology (Oxford). 2018;57:1222-1227 pubmed publisher
Alvarez Rodriguez L, Riancho Zarrabeitia L, Calvo Alén J, Lopez Hoyos M, Martinez Taboada V. Peripheral B-Cell Subset Distribution in Primary Antiphospholipid Syndrome. Int J Mol Sci. 2018;19: pubmed publisher
Heremans J, Garcia Perez J, Turro E, Schlenner S, Casteels I, Collin R, et al. Abnormal differentiation of B cells and megakaryocytes in patients with Roifman syndrome. J Allergy Clin Immunol. 2018;142:630-646 pubmed publisher
Smets I, Fiddes B, Garcia Perez J, He D, Mallants K, Liao W, et al. Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells. Brain. 2018;141:786-796 pubmed publisher
Fu Y, Wang L, Xie C, Zou K, Tu L, Yan W, et al. Comparison of non-invasive biomarkers faecal BAFF, calprotectin and FOBT in discriminating IBS from IBD and evaluation of intestinal inflammation. Sci Rep. 2017;7:2669 pubmed publisher
Wang S, Yang T, Wan J, Zhang Y, Fan Y. Elevated C-X-C motif ligand 13 and B-cell-activating factor levels in neuromyelitis optica during remission. Brain Behav. 2017;7:e00648 pubmed publisher
Pranzatelli M, Tate E, Allison T. Case-control, exploratory study of cerebrospinal fluid chemokines/cytokines and lymphocyte subsets in childhood Tourette syndrome with positive streptococcal markers. Cytokine. 2017;96:49-53 pubmed publisher
Ajeganova S, Tesfa D, Hagglund H, Fadeel B, Vedin I, Zignego A, et al. Effect of FCGR polymorphism on the occurrence of late-onset neutropenia and flare-free survival in rheumatic patients treated with rituximab. Arthritis Res Ther. 2017;19:44 pubmed publisher
Parodis I, Sjöwall C, Jönsen A, Ramsköld D, Zickert A, Frodlund M, et al. Smoking and pre-existing organ damage reduce the efficacy of belimumab in systemic lupus erythematosus. Autoimmun Rev. 2017;16:343-351 pubmed publisher
Gyllemark P, Forsberg P, Ernerudh J, Henningsson A. Intrathecal Th17- and B cell-associated cytokine and chemokine responses in relation to clinical outcome in Lyme neuroborreliosis: a large retrospective study. J Neuroinflammation. 2017;14:27 pubmed publisher
Puthenparampil M, Federle L, Miante S, Zito A, Toffanin E, Ruggero S, et al. BAFF Index and CXCL13 levels in the cerebrospinal fluid associate respectively with intrathecal IgG synthesis and cortical atrophy in multiple sclerosis at clinical onset. J Neuroinflammation. 2017;14:11 pubmed publisher
Lu B, Zhang B, Wang L, Ma C, Liu X, Zhao Y, et al. Hepatitis B Virus e Antigen Regulates Monocyte Function and Promotes B Lymphocyte Activation. Viral Immunol. 2017;30:35-44 pubmed publisher
Yamada T, Ogi K, Sakashita M, Kanno M, Kubo S, Ito Y, et al. Toll-like receptor ligands induce cytokine and chemokine production in human inner ear endolymphatic sac fibroblasts. Auris Nasus Larynx. 2017;44:398-403 pubmed publisher
Dijkstra D, Meyer Bahlburg A. Human Basophils Modulate Plasma Cell Differentiation and Maturation. J Immunol. 2017;198:229-238 pubmed
Zhang L, Li N, Yang L, Zhang J, Weng H, Zou L. Serum B-cell activating factor predicts prognosis in nasal type, extranodal NK/T cell lymphoma. Cytokine. 2016;88:196-198 pubmed publisher
Flint S, Gibson A, Lucas G, Nandigam R, Taylor L, Provan D, et al. A distinct plasmablast and naïve B-cell phenotype in primary immune thrombocytopenia. Haematologica. 2016;101:698-706 pubmed publisher
Borhis G, Burelout C, Chaoul N, Smith N, Goujard C, Meyer L, et al. Plasmacytoid dendritic cells and myeloid cells differently contribute to B-cell-activating factor belonging to the tumor necrosis factor superfamily overexpression during primary HIV infection. AIDS. 2016;30:365-76 pubmed publisher
Bornacelly A, Mercado D, Acevedo N, Caraballo L. The strength of the antibody response to the nematode Ascaris lumbricoides inversely correlates with levels of B-Cell Activating Factor (BAFF). BMC Immunol. 2014;15:22 pubmed publisher
Neill D, Saint G, Bricio Moreno L, Fothergill J, Southern K, Winstanley C, et al. The B lymphocyte differentiation factor (BAFF) is expressed in the airways of children with CF and in lungs of mice infected with Pseudomonas aeruginosa. PLoS ONE. 2014;9:e95892 pubmed publisher
Yang C, Li N, Wang Y, Zhang P, Zhu Q, Li F, et al. Serum levels of B-cell activating factor in chronic hepatitis B virus infection: association with clinical diseases. J Interferon Cytokine Res. 2014;34:787-94 pubmed publisher
Müller N, Schulte D, Hillebrand S, Türk K, Hampe J, Schafmayer C, et al. B Lymphocyte Stimulator (BLyS) is expressed in human adipocytes in vivo and is related to obesity but not to insulin resistance. PLoS ONE. 2014;9:e94282 pubmed publisher
Scholzen A, Teirlinck A, Bijker E, Roestenberg M, Hermsen C, Hoffman S, et al. BAFF and BAFF receptor levels correlate with B cell subset activation and redistribution in controlled human malaria infection. J Immunol. 2014;192:3719-29 pubmed publisher
Palanichamy A, Bauer J, Yalavarthi S, Meednu N, Barnard J, Owen T, et al. Neutrophil-mediated IFN activation in the bone marrow alters B cell development in human and murine systemic lupus erythematosus. J Immunol. 2014;192:906-18 pubmed publisher
Giacomini E, Severa M, Rizzo F, Mechelli R, Annibali V, Ristori G, et al. IFN-? therapy modulates B-cell and monocyte crosstalk via TLR7 in multiple sclerosis patients. Eur J Immunol. 2013;43:1963-72 pubmed publisher
Raffaghello L, Fühlhuber V, Bianchi G, Conte M, Blaes F, Gambini C, et al. Role of BAFF in Opsoclonus-Myoclonus syndrome, a bridge between cancer and autoimmunity. J Leukoc Biol. 2013;94:183-91 pubmed publisher
Pranzatelli M, Tate E, McGee N, Travelstead A, Colliver J, Ness J, et al. BAFF/APRIL system in pediatric OMS: relation to severity, neuroinflammation, and immunotherapy. J Neuroinflammation. 2013;10:10 pubmed publisher
Pontikoglou C, Kastrinaki M, Klaus M, Kalpadakis C, Katonis P, Alpantaki K, et al. Study of the quantitative, functional, cytogenetic, and immunoregulatory properties of bone marrow mesenchymal stem cells in patients with B-cell chronic lymphocytic leukemia. Stem Cells Dev. 2013;22:1329-41 pubmed publisher
Saussine A, Tazi A, Feuillet S, Rybojad M, Juillard C, Bergeron A, et al. Active chronic sarcoidosis is characterized by increased transitional blood B cells, increased IL-10-producing regulatory B cells and high BAFF levels. PLoS ONE. 2012;7:e43588 pubmed publisher
Benito Miguel M, García Carmona Y, Balsa A, Bautista Caro M, Arroyo Villa I, Cobo Ibáñez T, et al. IL-15 expression on RA synovial fibroblasts promotes B cell survival. PLoS ONE. 2012;7:e40620 pubmed publisher
Chaoul N, Burelout C, Peruchon S, van Buu B, Laurent P, Proust A, et al. Default in plasma and intestinal IgA responses during acute infection by simian immunodeficiency virus. Retrovirology. 2012;9:43 pubmed publisher
Ohmatsu H, Sugaya M, Miyagaki T, Suga H, Fujita H, Asano Y, et al. BAFF levels are increased in lesional skin and sera in patients with cutaneous T-cell lymphoma. Br J Dermatol. 2012;167:359-67 pubmed publisher
Pyrpasopoulou A, Balaska E, Triantafyllou A, Anyfanti P, Aslanidis S, Douma S. B-cell activating factor levels in rheumatoid arthritis patients in response to treatment with biologics. J Interferon Cytokine Res. 2012;32:338-40 pubmed publisher
Barbosa R, Silva S, Silva S, Melo A, Pedro E, Barbosa M, et al. Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-cell homeostasis and B-cell differentiation. PLoS ONE. 2011;6:e22848 pubmed publisher
Sarantopoulos S, Stevenson K, Kim H, Washel W, Bhuiya N, Cutler C, et al. Recovery of B-cell homeostasis after rituximab in chronic graft-versus-host disease. Blood. 2011;117:2275-83 pubmed publisher
Kuzmina Z, Greinix H, Weigl R, Körmöczi U, Rottal A, Frantal S, et al. Significant differences in B-cell subpopulations characterize patients with chronic graft-versus-host disease-associated dysgammaglobulinemia. Blood. 2011;117:2265-74 pubmed publisher
Sugalski J, Rodriguez B, Moir S, Anthony D. Peripheral blood B cell subset skewing is associated with altered cell cycling and intrinsic resistance to apoptosis and reflects a state of immune activation in chronic hepatitis C virus infection. J Immunol. 2010;185:3019-27 pubmed publisher
Zarkhin V, Li L, Sarwal M. BAFF may modulate the rate of B-cell repopulation after rituximab therapy for acute renal transplant rejection. Transplantation. 2009;88:1229-30 pubmed publisher
Chauhan D, Singh A, Brahmandam M, Carrasco R, Bandi M, Hideshima T, et al. Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target. Cancer Cell. 2009;16:309-23 pubmed publisher
Thompson S, Jones J, Cox A, Compston D, Coles A. B-cell reconstitution and BAFF after alemtuzumab (Campath-1H) treatment of multiple sclerosis. J Clin Immunol. 2010;30:99-105 pubmed publisher
Bloom D, Chang Z, Pauly K, Kwun J, Fechner J, Hayes C, et al. BAFF is increased in renal transplant patients following treatment with alemtuzumab. Am J Transplant. 2009;9:1835-45 pubmed publisher
Bojarska Junak A, Hus I, Chocholska S, Wasik Szczepanek E, Sieklucka M, Dmoszynska A, et al. BAFF and APRIL expression in B-cell chronic lymphocytic leukemia: correlation with biological and clinical features. Leuk Res. 2009;33:1319-27 pubmed publisher
Fühlhuber V, Bick S, Kirsten A, Hahn A, Gerriets T, Tschernatsch M, et al. Elevated B-cell activating factor BAFF, but not APRIL, correlates with CSF cerebellar autoantibodies in pediatric opsoclonus-myoclonus syndrome. J Neuroimmunol. 2009;210:87-91 pubmed publisher
Nagel A, Podstawa E, Eickmann M, Muller H, Hertl M, Eming R. Rituximab mediates a strong elevation of B-cell-activating factor associated with increased pathogen-specific IgG but not autoantibodies in pemphigus vulgaris. J Invest Dermatol. 2009;129:2202-10 pubmed publisher
Takeda T, Sakurai Y, Tatsumi K, Kato J, Kasuda S, Yoshioka A, et al. Elevation of B cell-activating factor belonging to the tumour necrosis factor [corrected] family (BAFF) in haemophilia A patients with inhibitor. Thromb Haemost. 2009;101:408-10 pubmed
Sarantopoulos S, Stevenson K, Kim H, Cutler C, Bhuiya N, Schowalter M, et al. Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease. Blood. 2009;113:3865-74 pubmed publisher
Zdzisinska B, Bojarska Junak A, Dmoszynska A, Kandefer Szerszen M. Abnormal cytokine production by bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells. Arch Immunol Ther Exp (Warsz). 2008;56:207-21 pubmed publisher
Kato A, Peters A, Suh L, Carter R, Harris K, Chandra R, et al. Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 2008;121:1385-92, 1392.e1-2 pubmed publisher
Breitkreutz I, Raab M, Vallet S, Hideshima T, Raje N, Chauhan D, et al. Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma. Br J Haematol. 2007;139:55-63 pubmed
Tai Y, Li X, Breitkreutz I, Song W, Neri P, Catley L, et al. Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment. Cancer Res. 2006;66:6675-82 pubmed
product information
master code :
DBLYS0B
SKU :
DBLYS0B
product name :
Human BAFF/BLyS/TNFSF13B Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Human BAFF/BLyS/TNFSF13B Quantikine ELISA Kit from R&D Systems quantifies human BAFF/BLyS/TNFSF13B in cell culture supernates (25 ul), serum (25 ul), edta plasma (25 ul), heparin plasma (25 ul).
target :
BAFF/BLyS/TNFSF13B
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human BAFF/BLyS
gene symbol :
TNFSF13B
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (25 uL), Serum (25 uL), EDTA Plasma (25 uL), Heparin Plasma (25 uL)
elisaSensitivity :
6.44 pg/mL
elisaRange :
62.50 - 4000 pg/mL
top caption :
Human BAFF/BLyS/TNFSF13B ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human BAFF/BLyS Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human BAFF/BLyS in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human BAFF/BLyS and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human BAFF/BLyS showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human BAFF.
alt names :
ApoL related ligand TALL-1, B lymphocyte stimulator, BAFFB-cell activating factor, B-cell-activating factor, BLyS, BLYSB-lymphocyte stimulator, CD257, CD257 antigen, Dendritic cell-derived TNF-like molecule, DTL, TALL1, TALL-1delta BAFF, TALL1Delta4 BAFF, THANK, TNF and ApoL-related leukocyte expressed ligand 1, TNF- and APOL-related leukocyte expressed ligand 1, TNF homolog that activates apoptosis, TNFSF13B, TNFSF20, tumor necrosis factor (ligand) superfamily, member 13b, tumor necrosis factor (ligand) superfamily, member 20, tumor necrosis factor ligand superfamily member 13B, tumor necrosis factor superfamily, member 13b, tumor necrosis factor-like protein ZTNF4, ZTNF4
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.