Human Amphiregulin Quantikine ELISA Kit | R&D Systems DAR00 product information

product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human Amphiregulin Quantikine ELISA Kit

catalog :

DAR00

quantity :

1 Kit

price :

655 USD

more info or order :

R&D Systems product webpage

citations: 19

Reference
Yoon S, Jeong Y, Ryu J, Lee S, Chae B, Yu J, et al. 17β-Estradiol Promotes Tumorigenicity Through an Autocrine AREG/EGFR Loop in ER-α-Positive Breast Cancer Cells. Cells. 2025;14: pubmed publisher
Das A, Ariyakumar G, Gupta N, Kamdar S, Barugahare A, Deveson Lucas D, et al. Identifying immune signatures of sepsis to increase diagnostic accuracy in very preterm babies. Nat Commun. 2024;15:388 pubmed publisher
Kamentseva R, Kharchenko M, Gabdrahmanova G, Kotov M, Kosheverova V, Kornilova E. EGF, TGF-α and Amphiregulin Differently Regulate Endometrium-Derived Mesenchymal Stromal/Stem Cells. Int J Mol Sci. 2023;24: pubmed publisher
Liu Y, Zhong Y, Shen X, Guo X, Wu R, Yang T, et al. Luteinizing hormone stimulates the expression of amphiregulin in human theca cells. J Ovarian Res. 2022;15:129 pubmed publisher
Sieber B, Lu F, Stribbling S, Grieve A, Ryan A, Freeman M. iRhom2 regulates ERBB signalling to promote KRAS-driven tumour growth of lung cancer cells. J Cell Sci. 2022;135: pubmed publisher
Vogeley C, Sondermann N, Woeste S, Momin A, Gilardino V, Hartung F, et al. Unraveling the differential impact of PAHs and dioxin-like compounds on AKR1C3 reveals the EGFR extracellular domain as a critical determinant of the AHR response. Environ Int. 2022;158:106989 pubmed publisher
Kim S, Park H, Kim K, Kim J, Sung J, Nam M, et al. Amphiregulin can predict treatment resistance to palliative first-line cetuximab plus FOLFIRI chemotherapy in patients with RAS wild-type metastatic colorectal cancer. Sci Rep. 2021;11:23803 pubmed publisher
Fukushima K, Itaba N, Kono Y, Okazaki S, Enokida S, Kuranobu N, et al. Secreted matrix metalloproteinase-14 is a predictor for antifibrotic effect of IC-2-engineered mesenchymal stem cell sheets on liver fibrosis in mice. Regen Ther. 2021;18:292-301 pubmed publisher
Stancil I, Michalski J, Davis Hall D, Chu H, Park J, Magin C, et al. Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional. Nat Commun. 2021;12:4566 pubmed publisher
Wiedemann A, Foucat E, Hocini H, Lefebvre C, Hejblum B, Durand M, et al. Long-lasting severe immune dysfunction in Ebola virus disease survivors. Nat Commun. 2020;11:3730 pubmed publisher
Wang L, Wang L, Zhang H, Lu J, Zhang Z, Wu H, et al. AREG mediates the epithelial‑mesenchymal transition in pancreatic cancer cells via the EGFR/ERK/NF‑κB signalling pathway. Oncol Rep. 2020;43:1558-1568 pubmed publisher
Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, et al. Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. Aging Cell. 2019;18:e13027 pubmed publisher
Jia J, Li C, Yang J, Wang X, Li R, Luo S, et al. Yes-associated protein promotes the abnormal proliferation of psoriatic keratinocytes via an amphiregulin dependent pathway. Sci Rep. 2018;8:14513 pubmed publisher
Mésange P, Bouygues A, Ferrand N, Sabbah M, Escargueil A, Savina A, et al. Combinations of Bevacizumab and Erlotinib Show Activity in Colorectal Cancer Independent of RAS Status. Clin Cancer Res. 2018;24:2548-2558 pubmed publisher
Alvarado D, Ligon G, Lillquist J, Seibel S, Wallweber G, Neumeister V, et al. ErbB activation signatures as potential biomarkers for anti-ErbB3 treatment in HNSCC. PLoS ONE. 2017;12:e0181356 pubmed publisher
Holtan S, Khera N, Levine J, Chai X, Storer B, Liu H, et al. Late acute graft-versus-host disease: a prospective analysis of clinical outcomes and circulating angiogenic factors. Blood. 2016;128:2350-2358 pubmed publisher
Trussoni C, Tabibian J, Splinter P, O Hara S. Lipopolysaccharide (LPS)-Induced Biliary Epithelial Cell NRas Activation Requires Epidermal Growth Factor Receptor (EGFR). PLoS ONE. 2015;10:e0125793 pubmed publisher
Yonesaka K, Satoh T, Ueda S, Yoshida T, Takeda M, Shimizu T, et al. Circulating hepatocyte growth factor is correlated with resistance to cetuximab in metastatic colorectal cancer. Anticancer Res. 2015;35:1683-9 pubmed
Zhang Z, Dong Z, Lauxen I, Filho M, Nor J. Endothelial cell-secreted EGF induces epithelial to mesenchymal transition and endows head and neck cancer cells with stem-like phenotype. Cancer Res. 2014;74:2869-81 pubmed publisher

image

image 1 :

Human Amphiregulin ELISA Standard Curve

product information

brand :

R&D Systems

catalog number base :

DAR00

SKU :

DAR00

product name :

Human Amphiregulin Quantikine ELISA Kit

units size :

1 Kit

description :

The Human Amphiregulin Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human Amphiregulin in cell culture supernates (50 ul), cell lysates (50 ul), serum (50 ul), edta plasma (50 ul), heparin plasma (50 ul), saliva (50 ul), urine (50 ul).

target :

Amphiregulin

category :

ELISAs

all_available conjugate :

HRP

species :

Human

specificity :

Recombinant and natural human Amphiregulin

gene symbol :

AREG

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Cell Lysates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL), Saliva (50 uL), Urine (50 uL)

elisaSensitivity :

3.56 pg/mL

elisaRange :

15.60 - 1000 pg/mL

top caption :

Human Amphiregulin ELISA Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human Amphiregulin Immunoassay is a 4.5 hour solid phase ELISA designed to measure human Amphiregulin in cell culture supernates, cell lysates serum, plasma, saliva, and urine. It contains E. coli -derived recombinant human Amphiregulin and has been shown to accurately quantitate the recombinant factor. Results obtained with natural human Amphiregulin showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Amphiregulin.

alt names :

amphiregulin, AR, AREG, AREGB, Colorectum cell-derived growth factor, CRDGF, MGC13647, schwannoma-derived growth factor, SDGF

storage :

Store the unopened product at 2 - 8 Â°C. Do not use past expiration date.

more info or order :

R&D Systems product webpage