This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human Angiopoietin-2 Quantikine ELISA Kit
catalog :
DANG20
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 105
Reference
Bucher V, Graf H, Zander J, Liebchen U, Hackner D, Gr xe4 fe C, et al. Angiopoietin II in Critically Ill Septic Patients: A Post Hoc Analysis of the DRAK Study. Biomedicines. 2024;12: pubmed publisher
Keller S, Kunz U, Schmid U, Beusmans J, B xfc chert M, He M, et al. Comprehensive biomarker and modeling approach to support dose finding for BI 836880, a VEGF/Ang-2 inhibitor. J Transl Med. 2024;22:934 pubmed publisher
Serlo M, Inkinen N, Lakkisto P, Valkonen M, Pulkkinen A, Selander T, et al. Fluid bolus increases plasma hyaluronan concentration compared to follow-up strategy without a bolus in oliguric intensive care unit patients. Sci Rep. 2024;14:20808 pubmed publisher
Roos Mattila M, Kaprio T, Mustonen H, Hagstr xf6 m J, Saharinen P, Haglund C, et al. The possible dual role of Ang-2 in the prognosis of pancreatic cancer. Sci Rep. 2023;13:18725 pubmed publisher
Arakélian L, Lion J, Churlaud G, Bargui R, Thierry B, Mutabazi E, et al. Endothelial CD34 expression and regulation of immune cell response in-vitro. Sci Rep. 2023;13:13512 pubmed publisher
Szymczak A, Kusztal M, Go x142 x119 biowski T, Letachowicz K, Go x17a dzik A, Ko x15b cielska Kasprzak K, et al. High Plasma Angiopoietin-2 Levels Predict the Need to Initiate Dialysis within Two Years in Patients with Chronic Kidney Disease. Int J Mol Sci. 2023;24: pubmed publisher
Balerdi Sarasola L, Parolo C, Fleitas P, Cruz A, Subir xe0 C, Rodr xed guez Valero N, et al. Host biomarkers for early identification of severe imported Plasmodium falciparum malaria. Travel Med Infect Dis. 2023;54:102608 pubmed publisher
Subramanian N, Hofwimmer K, Tavira B, Massier L, Andersson D, Arner P, et al. Adipose tissue specific CCL18 associates with cardiometabolic diseases in non-obese individuals implicating CD4+ T cells. Cardiovasc Diabetol. 2023;22:84 pubmed publisher
Tsai T, Alwees M, Asaad M, Theile J, Kakkassery V, Dick H, et al. Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy. PLoS ONE. 2023;18:e0280488 pubmed publisher
Dumnicka P, Mazur Laskowska M, Ceranowicz P, Sporek M, Kolber W, Tiso x144 czyk J, et al. Acute Changes in Serum Creatinine and Kinetic Glomerular Filtration Rate Estimation in Early Phase of Acute Pancreatitis. J Clin Med. 2022;11: pubmed publisher
Critelli R, Milosa F, Romanzi A, Lasagni S, Marcelli G, Di Marco L, et al. Upregulation of the oestrogen target gene SIX1 is associated with higher growth speed and decreased survival in HCV-positive women with hepatocellular carcinoma. Oncol Lett. 2022;24:395 pubmed publisher
Ni B, Chen S, Ryan K, Maitland M, Farrar J, Witzenrath M, et al. Selective adipocyte loss of Angiopoietin-2 prompts female-specific obesity and metabolic syndrome. Mol Metab. 2022;65:101588 pubmed publisher
Hultstr xf6 m M, Fromell K, Larsson A, Persson B, Nilsson B, Quaggin S, et al. Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation-A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients. Biomedicines. 2022;10: pubmed publisher
Kaur J, Kamboj K, Yadav A, Kaur P, Kumar V, Jha V. Cholecalciferol supplementation and angiogenic markers in chronic kidney disease. PLoS ONE. 2022;17:e0268946 pubmed publisher
Qin Y, Dinabandhu A, Cao X, Sanchez J, Jee K, Rodrigues M, et al. ANGPTL4 influences the therapeutic response of patients with neovascular age-related macular degeneration by promoting choroidal neovascularization. JCI Insight. 2022;7: pubmed publisher
Yamada Y, Zhong Y, Miki S, Taura A, Rabbitts T. The transcription factor complex LMO2/TAL1 regulates branching and endothelial cell migration in sprouting angiogenesis. Sci Rep. 2022;12:7226 pubmed publisher
Haffke M, Freitag H, Rudolf G, Seifert M, Doehner W, Scherbakov N, et al. Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS). J Transl Med. 2022;20:138 pubmed publisher
Karabid N, Wiedemann T, Gulde S, Mohr H, Segaran R, Geppert J, et al. Angpt2/Tie2 autostimulatory loop controls tumorigenesis. EMBO Mol Med. 2022;14:e14364 pubmed publisher
Sibila O, Perea L, Albacar N, Mois xe9 s J, Cruz T, Mendoza N, et al. Elevated plasma levels of epithelial and endothelial cell markers in COVID-19 survivors with reduced lung diffusing capacity six months after hospital discharge. Respir Res. 2022;23:37 pubmed publisher
Woś J, Chocholska S, Kowalska W, Tomczak W, Szymańska A, Karczmarczyk A, et al. Prognostic Value of Tie2-Expressing Monocytes in Chronic Lymphocytic Leukemia Patients. Cancers (Basel). 2021;13: pubmed publisher
Fujiwara Sumiyoshi S, Ueda Y, Fujikawa M, Osaki M, Yamanaka N, Matsumoto T. Mucopolysaccharide polysulfate promotes microvascular stabilization and barrier integrity of dermal microvascular endothelial cells via activation of the angiopoietin-1/Tie2 pathway. J Dermatol Sci. 2021;103:25-32 pubmed publisher
Barber B, Grigg M, Piera K, Chen Y, William T, Weinberg J, et al. Endothelial glycocalyx degradation and disease severity in Plasmodium vivax and Plasmodium knowlesi malaria. Sci Rep. 2021;11:9741 pubmed publisher
Seki T, Yanaihara N, SHAPIRO J, Saito M, Tabata J, Yokomizo R, et al. Interleukin-6 as an enhancer of anti-angiogenic therapy for ovarian clear cell carcinoma. Sci Rep. 2021;11:7689 pubmed publisher
Crake R, Strother M, Phillips E, Doogue M, Zhang M, Frampton C, et al. Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study. Sci Rep. 2021;11:5648 pubmed publisher
Osawa Y, Yoshio S, Aoki Y, Korenaga M, Imamura M, Oide T, et al. Blood angiopoietin-2 predicts liver angiogenesis and fibrosis in hepatitis C patients. BMC Gastroenterol. 2021;21:55 pubmed publisher
Hannappe M, Arnould L, Meloux A, Mouhat B, Bichat F, Zeller M, et al. Vascular density with optical coherence tomography angiography and systemic biomarkers in low and high cardiovascular risk patients. Sci Rep. 2020;10:16718 pubmed publisher
Kennedy S, Morrissey M, Dunne M, O Connell F, Butler C, Cathcart M, et al. Combining 1,4-dihydroxy quininib with Bevacizumab/FOLFOX alters angiogenic and inflammatory secretions in ex vivo colorectal tumors. BMC Cancer. 2020;20:952 pubmed publisher
Terlikowska K, Dobrzycka B, Terlikowski R, Sienkiewicz A, Kinalski M, Terlikowski S. Clinical value of selected markers of angiogenesis, inflammation, insulin resistance and obesity in type 1 endometrial cancer. BMC Cancer. 2020;20:921 pubmed publisher
Wajda J, Dumnicka P, Sporek M, Maziarz B, Kolber W, Zabek Adamska A, et al. Does Beta-Trace Protein (BTP) Outperform Cystatin C as a Diagnostic Marker of Acute Kidney Injury Complicating the Early Phase of Acute Pancreatitis?. J Clin Med. 2020;9: pubmed publisher
Gao C, Gong Z, Wang D, Huang J, Qian Y, Nie M, et al. Hematoma-derived exosomes of chronic subdural hematoma promote abnormal angiogenesis and inhibit hematoma absorption through miR-144-5p. Aging (Albany NY). 2019;11:12147-12164 pubmed publisher
Scurt F, Menne J, Brandt S, Bernhardt A, Mertens P, Haller H, et al. Systemic Inflammation Precedes Microalbuminuria in Diabetes. Kidney Int Rep. 2019;4:1373-1386 pubmed publisher
Klinger M, Zugmaier G, Nägele V, Goebeler M, Brandl C, Stelljes M, et al. Adhesion of T Cells to Endothelial Cells Facilitates Blinatumomab-Associated Neurologic Adverse Events. Cancer Res. 2020;80:91-101 pubmed publisher
Kazune S, Caica A, Volceka K, Suba O, Rubins U, Grabovskis A. Relationship of mottling score, skin microcirculatory perfusion indices and biomarkers of endothelial dysfunction in patients with septic shock: an observational study. Crit Care. 2019;23:311 pubmed publisher
Dekker N, van Leeuwen A, van Strien W, Majolee J, Szulcek R, Vonk A, et al. Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels. Crit Care. 2019;23:117 pubmed publisher
de Oliveira Neves F, Araújo C, de Freitas D, Arruda B, de Macêdo Filho L, Salles V, et al. Fibroblast growth factor 23, endothelium biomarkers and acute kidney injury in critically-ill patients. J Transl Med. 2019;17:121 pubmed publisher
Wang R, Yamada T, Arai S, Fukuda K, Taniguchi H, Tanimoto A, et al. Distribution and Activity of Lenvatinib in Brain Tumor Models of Human Anaplastic Thyroid Cancer Cells in Severe Combined Immune Deficient Mice. Mol Cancer Ther. 2019;18:947-956 pubmed publisher
Varas Godoy M, Acuña Gallardo S, Venegas Duarte S, Hill C, Caceres Verschae A, Realini O, et al. Angiogenic Properties of Menstrual Stem Cells Are Impaired in Women with a History of Preeclampsia. Stem Cells Int. 2019;2019:1916542 pubmed publisher
Kolber W, Dumnicka P, Maraj M, Kusnierz Cabala B, Ceranowicz P, Pędziwiatr M, et al. Does the Automatic Measurement of Interleukin 6 Allow for Prediction of Complications during the First 48 h of Acute Pancreatitis?. Int J Mol Sci. 2018;19: pubmed publisher
Shi Y, Yan H, Yuan J, Zhang H, Huang J, Ni Z, et al. Different patterns of inflammatory and angiogenic factors are associated with peritoneal small solute transport and peritoneal protein clearance in peritoneal dialysis patients. BMC Nephrol. 2018;19:119 pubmed publisher
Robinson C, Tsang L, Solomon A, Woodiwiss A, Gunter S, Mer M, et al. Nesfatin-1 and visfatin expression is associated with reduced atherosclerotic disease risk in patients with rheumatoid arthritis. Peptides. 2018;102:31-37 pubmed publisher
Meyer N, Reilly J, Feng R, Christie J, Hazen S, Albert C, et al. Myeloperoxidase-derived 2-chlorofatty acids contribute to human sepsis mortality via acute respiratory distress syndrome. JCI Insight. 2017;2: pubmed publisher
Moritz F, Schniering J, Distler J, Gay R, Gay S, Distler O, et al. Tie2 as a novel key factor of microangiopathy in systemic sclerosis. Arthritis Res Ther. 2017;19:105 pubmed publisher
Gozal D, Khalyfa A, Qiao Z, Smith D, Philby M, Koren D, et al. Angiopoietin-2 and soluble Tie-2 receptor plasma levels in children with obstructive sleep apnea and obesity. Obesity (Silver Spring). 2017;25:1083-1090 pubmed publisher
Demolli S, Doddaballapur A, Devraj K, Stark K, Manavski Y, Eckart A, et al. Shear stress-regulated miR-27b controls pericyte recruitment by repressing SEMA6A and SEMA6D. Cardiovasc Res. 2017;113:681-691 pubmed publisher
Wang K, Liu W, Song Y, Wu X, Zhang Y, Li S, et al. The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration. Lab Invest. 2017;97:971-982 pubmed publisher
Dumnicka P, Kusnierz Cabala B, Sporek M, Mazur Laskowska M, Gil K, Kuzniewski M, et al. Serum Concentrations of Angiopoietin-2 and Soluble fms-Like Tyrosine Kinase 1 (sFlt-1) Are Associated with Coagulopathy among Patients with Acute Pancreatitis. Int J Mol Sci. 2017;18: pubmed publisher
Kuć P, Charkiewicz R, Klasa Mazurkiewicz D, Milczek T, Mroczko B, Nikliński J, et al. Profiling of selected angiogenesis-related genes in serous ovarian cancer patients. Adv Med Sci. 2017;62:116-120 pubmed publisher
Tsai Y, Lee C, Chiu Y, Kuo H, Lee S, Hwang S, et al. Angiopoietin-2, Angiopoietin-1 and subclinical cardiovascular disease in Chronic Kidney Disease. Sci Rep. 2016;6:39400 pubmed publisher
Jiang S, Li Y, Lin T, Yuan L, Li Y, Wu S, et al. IL-35 Inhibits Angiogenesis through VEGF/Ang2/Tie2 Pathway in Rheumatoid Arthritis. Cell Physiol Biochem. 2016;40:1105-1116 pubmed
Hossain M, Shifat R, Johnson D, Bedford M, Gabrusiewicz K, Cortes Santiago N, et al. TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1. Sci Adv. 2016;2:e1501290 pubmed
Chou C, Modo M. Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling. Sci Rep. 2016;6:29029 pubmed publisher
Dauwe D, Pelacho B, Wibowo A, Walravens A, Verdonck K, Gillijns H, et al. Neovascularization Potential of Blood Outgrowth Endothelial Cells From Patients With Stable Ischemic Heart Failure Is Preserved. J Am Heart Assoc. 2016;5:e002288 pubmed publisher
Jongman R, van Klarenbosch J, Molema G, Zijlstra J, de Vries A, van Meurs M. Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass. PLoS ONE. 2015;10:e0136205 pubmed publisher
Salazar R, Capdevila J, Laquente B, Manzano J, Pericay C, Villacampa M, et al. A randomized phase II study of capecitabine-based chemoradiation with or without bevacizumab in resectable locally advanced rectal cancer: clinical and biological features. BMC Cancer. 2015;15:60 pubmed publisher
Verstraete M, Debucquoy A, Dekervel J, Van Pelt J, Verslype C, Devos E, et al. Combining bevacizumab and chemoradiation in rectal cancer. Translational results of the AXEBeam trial. Br J Cancer. 2015;112:1314-25 pubmed publisher
Dessein P, Hsu H, Tsang L, Millen A, Woodiwiss A, Norton G, et al. Kidney function, endothelial activation and atherosclerosis in black and white Africans with rheumatoid arthritis. PLoS ONE. 2015;10:e0121693 pubmed publisher
Zheng X, Ohsaki E, Ueda K. Mechanism of angiopoietin-1 upregulation in Kaposi's sarcoma-associated herpesvirus-infected PEL cell lines. J Virol. 2015;89:4786-97 pubmed publisher
Tsai Y, Chiu Y, Tsai J, Kuo H, Lee S, Hung C, et al. Association of angiopoietin-2 with renal outcome in chronic kidney disease. PLoS ONE. 2014;9:e108862 pubmed publisher
Gomes L, Alves Junior E, Rodrigues Jesus C, Nery A, Gasquez Martin T, Fontes C. Angiopoietin-2 and angiopoietin-2/angiopoietin-1 ratio as indicators of potential severity of Plasmodium vivax malaria in patients with thrombocytopenia. PLoS ONE. 2014;9:e109246 pubmed publisher
Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla Herttuala S, et al. Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer. BMC Cancer. 2014;14:696 pubmed publisher
Voigtländer T, David S, Thamm K, Schlue J, Metzger J, Manns M, et al. Angiopoietin-2 and biliary diseases: elevated serum, but not bile levels are associated with cholangiocarcinoma. PLoS ONE. 2014;9:e97046 pubmed publisher
Krautkrämer E, Grouls S, Hettwer D, Rafat N, Tönshoff B, Zeier M. Mobilization of circulating endothelial progenitor cells correlates with the clinical course of hantavirus disease. J Virol. 2014;88:483-9 pubmed publisher
Wertenbroek M, Schepers M, Kamminga Rasker H, Bottema J, Muller Kobold A, Roelofsen H, et al. Clinical outcome, proteome kinetics and angiogenic factors in serum after thermoablation of colorectal liver metastases. BMC Cancer. 2013;13:266 pubmed publisher
Schauer D, Starlinger P, Reiter C, Jahn N, Zajc P, Buchberger E, et al. Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer. PLoS ONE. 2012;7:e44450 pubmed publisher
Ghosh C, Mukherjee A, David S, Knaus U, Stearns Kurosawa D, Kurosawa S, et al. Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax. Proc Natl Acad Sci U S A. 2012;109:10024-9 pubmed publisher
Llovet J, Peña C, Lathia C, Shan M, Meinhardt G, Bruix J. Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma. Clin Cancer Res. 2012;18:2290-300 pubmed publisher
Rasul S, Reiter M, Ilhan A, Lampichler K, Wagner L, Kautzky Willer A. Circulating angiopoietin-2 and soluble Tie-2 in type 2 diabetes mellitus: a cross-sectional study. Cardiovasc Diabetol. 2011;10:55 pubmed publisher
Ricciuto D, dos Santos C, Hawkes M, Toltl L, Conroy A, Rajwans N, et al. Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med. 2011;39:702-10 pubmed publisher
Volkova E, Willis J, Wells J, Robinson B, Dachs G, Currie M. Association of angiopoietin-2, C-reactive protein and markers of obesity and insulin resistance with survival outcome in colorectal cancer. Br J Cancer. 2011;104:51-9 pubmed publisher
Li T, Cheng K, Malliaras K, Matsushita N, Sun B, Marbán L, et al. Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair. Cardiovasc Res. 2011;89:157-65 pubmed publisher
Maffei R, Martinelli S, Santachiara R, Rossi D, Guarnotta C, Sozzi E, et al. Angiopoietin-2 plasma dosage predicts time to first treatment and overall survival in chronic lymphocytic leukemia. Blood. 2010;116:584-92 pubmed publisher
Boucherat O, Franco Montoya M, Delacourt C, Martinovic J, Masse V, Elie C, et al. Defective angiogenesis in hypoplastic human fetal lungs correlates with nitric oxide synthase deficiency that occurs despite enhanced angiopoietin-2 and VEGF. Am J Physiol Lung Cell Mol Physiol. 2010;298:L849-56 pubmed publisher
Berisha B, Meyer H, Schams D. Effect of prostaglandin F2 alpha on local luteotropic and angiogenic factors during induced functional luteolysis in the bovine corpus luteum. Biol Reprod. 2010;82:940-7 pubmed publisher
Sorensen A, Batchelor T, Zhang W, Chen P, Yeo P, Wang M, et al. A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients. Cancer Res. 2009;69:5296-300 pubmed publisher
Hurliman A, Speroff L, Stouffer R, Patton P, Lee A, Molskness T. Changes in circulating levels and ratios of angiopoietins during pregnancy but not during the menstrual cycle and controlled ovarian stimulation. Fertil Steril. 2010;93:1493-9 pubmed publisher
Kumara H, Shantha Kumara H, Feingold D, Kalady M, Dujovny N, Senagore A, et al. Colorectal resection is associated with persistent proangiogenic plasma protein changes: postoperative plasma stimulates in vitro endothelial cell growth, migration, and invasion. Ann Surg. 2009;249:973-7 pubmed publisher
Labonté L, Li Y, Yang L, Gillingham A, Halpenny M, Giulivi A, et al. Increased plasma EPO and MIP-1 alpha are associated with recruitment of vascular progenitors but not CD34(+) cells in autologous peripheral blood stem cell grafts. Exp Hematol. 2009;37:673-8 pubmed publisher
Bourlev V, Iljasova N, Adamyan L, Larsson A, Olovsson M. Signs of reduced angiogenic activity after surgical removal of deeply infiltrating endometriosis. Fertil Steril. 2010;94:52-7 pubmed publisher
Helfrich I, Edler L, Sucker A, Thomas M, Christian S, Schadendorf D, et al. Angiopoietin-2 levels are associated with disease progression in metastatic malignant melanoma. Clin Cancer Res. 2009;15:1384-92 pubmed publisher
Serefhanoglu S, Goker H, Buyukasik Y, Turgut M, Sayinalp N, Haznedaroglu I, et al. Changes in vascular endothelial growth factor, angiopoietins, and Tie-2 levels with G-CSF stimulation in healthy donors. Ann Hematol. 2009;88:667-71 pubmed publisher
Yeo T, Lampah D, Gitawati R, Tjitra E, Kenangalem E, Piera K, et al. Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria. Proc Natl Acad Sci U S A. 2008;105:17097-102 pubmed publisher
FINDLEY C, Mitchell R, Duscha B, Annex B, Kontos C. Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease. J Am Coll Cardiol. 2008;52:387-93 pubmed publisher
Shim W, Lim S, Li S, Gu Y, Ong H, Song I, et al. Structural stability of neoangiogenic intramyocardial microvessels supports functional recovery in chronic ischemic myocardium. J Mol Cell Cardiol. 2008;45:70-80 pubmed publisher
Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, et al. Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp Hematol. 2008;36:1035-46 pubmed publisher
Ganter M, Cohen M, Brohi K, Chesebro B, Staudenmayer K, Rahn P, et al. Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?. Ann Surg. 2008;247:320-6 pubmed publisher
Choudhury A, Freestone B, Patel J, Lip G. Relationship of soluble CD40 ligand to vascular endothelial growth factor, angiopoietins, and tissue factor in atrial fibrillation: a link among platelet activation, angiogenesis, and thrombosis?. Chest. 2007;132:1913-9 pubmed
Kanazawa H, Tochino Y, Asai K. Angiopoietin-2 as a contributing factor of exercise-induced bronchoconstriction in asthmatic patients receiving inhaled corticosteroid therapy. J Allergy Clin Immunol. 2008;121:390-5 pubmed
Lee C, Tien H, Hu C, Chou W, Lin L. Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia. Br J Cancer. 2007;97:877-82 pubmed
Park J, Park K, Kim Y, Sheen S, Lee K, Lee H, et al. Serum angiopoietin-2 as a clinical marker for lung cancer. Chest. 2007;132:200-6 pubmed
Vart R, Nikitenko L, Lagos D, Trotter M, Cannon M, Bourboulia D, et al. Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoietin-2 expression in lymphatic endothelial cells. Cancer Res. 2007;67:4042-51 pubmed
Anagnostopoulos A, Eleftherakis Papaiakovou V, Kastritis E, Tsionos K, Bamias A, Meletis J, et al. Serum concentrations of angiogenic cytokines in Waldenstrom macroglobulinaemia: the ration of angiopoietin-1 to angiopoietin-2 and angiogenin correlate with disease severity. Br J Haematol. 2007;137:560-8 pubmed
Kanazawa H, Nomura S, Asai K. Roles of angiopoietin-1 and angiopoietin-2 on airway microvascular permeability in asthmatic patients. Chest. 2007;131:1035-41 pubmed
Niedzwiecki S, Stepien T, Kopeć K, Kuzdak K, Komorowski J, Krupinski R, et al. Angiopoietin 1 (Ang-1), angiopoietin 2 (Ang-2) and Tie-2 (a receptor tyrosine kinase) concentrations in peripheral blood of patients with thyroid cancers. Cytokine. 2006;36:291-5 pubmed
Caine G, Ryan P, Lip G, Blann A. Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients. Cancer Lett. 2007;251:296-301 pubmed
Bhandari V, Choo Wing R, Lee C, Zhu Z, Nedrelow J, Chupp G, et al. Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med. 2006;12:1286-93 pubmed
Fearon U, Mullan R, Markham T, Connolly M, Sullivan S, Poole A, et al. Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures. Arthritis Rheum. 2006;54:3152-62 pubmed
Molskness T, Stouffer R, Burry K, Gorrill M, Lee D, Patton P. Circulating levels of total angiopoietin-2 and the soluble Tie-2 receptor in women during ovarian stimulation and early gestation. Fertil Steril. 2006;86:1531-3 pubmed
Quartarone E, Alonci A, Allegra A, Bellomo G, Calabro L, D Angelo A, et al. Differential levels of soluble angiopoietin-2 and Tie-2 in patients with haematological malignancies. Eur J Haematol. 2006;77:480-5 pubmed
Caine G, Stonelake P, Lip G, Blann A. Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer. Cancer Lett. 2007;248:131-6 pubmed
Tseng J, Hsu S, Ho E, Hsieh Y, Wen M, Chou M. Differential expression of angiopoietin-1, angiopoietin-2, and Tie receptors in placentas from pregnancies complicated by placenta accreta. Am J Obstet Gynecol. 2006;194:564-71 pubmed
Furstenberger G, von Moos R, Lucas R, Thurlimann B, Senn H, Hamacher J, et al. Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer. Br J Cancer. 2006;94:524-31 pubmed
Koutroubakis I, Xidakis C, Karmiris K, Sfiridaki A, Kandidaki E, Kouroumalis E. Potential role of soluble angiopoietin-2 and Tie-2 in patients with inflammatory bowel disease. Eur J Clin Invest. 2006;36:127-32 pubmed
Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, et al. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol. 2005;175:6177-89 pubmed
Watanabe D, Suzuma K, Suzuma I, Ohashi H, Ojima T, Kurimoto M, et al. Vitreous levels of angiopoietin 2 and vascular endothelial growth factor in patients with proliferative diabetic retinopathy. Am J Ophthalmol. 2005;139:476-81 pubmed
Stahl A, Wenger A, Weber H, Stark G, Augustin H, Finkenzeller G. Bi-directional cell contact-dependent regulation of gene expression between endothelial cells and osteoblasts in a three-dimensional spheroidal coculture model. Biochem Biophys Res Commun. 2004;322:684-92 pubmed
product information
master code :
DANG20
SKU :
DANG20
product name :
Human Angiopoietin-2 Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Human Angiopoietin-2 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human Angiopoietin-2 in cell culture supernates (50 ul), serum (10 ul), edta plasma (10 ul), heparin plasma (10 ul), saliva (50 ul).
target :
Angiopoietin-2
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human Angiopoietin-2
gene symbol :
ANGPT2
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Saliva (50 uL)
elisaSensitivity :
21.3 pg/mL
elisaRange :
46.90 - 3000 pg/mL
top caption :
Human Angiopoietin-2 ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human Angiopoietin-2 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Angiopoietin-2 in cell culture supernates, serum, plasma, and saliva. It contains NS0-expressed recombinant human Angiopoietin-2 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Angiopoietin-2 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Angiopoietin-2.
alt names :
AGPT2, ANG2, ANG-2, angiopoietin 2, angiopoietin-2, angiopoietin-2a, angiopoietin-2B, angiopoitin 2, ANGPT2, Tie2-ligand
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.