Human Angiopoietin-1 Quantikine ELISA Kit | R&D Systems DANG10 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human Angiopoietin-1 Quantikine ELISA Kit

catalog :

DANG10

quantity :

1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))

price :

655 USD

citations: 55

Reference
Sch xf6 nborn M, Gregorczyk Maga I, Batko K, Maga M, Bogucka K, Gawlik K, et al. Angiogenic and Microvascular Status Alterations after Endovascular Revascularization of Lower Limb Arteries among Patients with Diabetic Foot Syndrome: A Prospective 12-Month Follow-Up Study. J Clin Med. 2023;12: pubmed publisher
Gregorczyk Maga I, Szustkiewicz Karo x144 A, Gajda M, Kapusta M, Maga W, Sch xf6 nborn M. The Concentration of Pro- and Antiangiogenic Factors in Saliva and Gingival Crevicular Fluid Compared to Plasma in Patients with Peripheral Artery Disease and Type 2 Diabetes. Biomedicines. 2023;11: pubmed publisher
Sch xf6 nborn M, Gregorczyk Maga I, Batko K, Bogucka K, Maga M, P x142 otek A, et al. Circulating Angiogenic Factors and Ischemic Diabetic Foot Syndrome Advancement-A Pilot Study. Biomedicines. 2023;11: pubmed publisher
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Tsai T, Alwees M, Asaad M, Theile J, Kakkassery V, Dick H, et al. Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy. PLoS ONE. 2023;18:e0280488 pubmed publisher
Moxon J, Kraeuter A, Phie J, Juliano S, Anderson G, Standley G, et al. Serum angiopoietin-1 concentration does not distinguish patients with ischaemic stroke from those presenting to hospital with ischaemic stroke mimics. BMC Cardiovasc Disord. 2022;22:462 pubmed publisher
Critelli R, Milosa F, Romanzi A, Lasagni S, Marcelli G, Di Marco L, et al. Upregulation of the oestrogen target gene SIX1 is associated with higher growth speed and decreased survival in HCV-positive women with hepatocellular carcinoma. Oncol Lett. 2022;24:395 pubmed publisher
Hultstr xf6 m M, Fromell K, Larsson A, Persson B, Nilsson B, Quaggin S, et al. Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation-A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients. Biomedicines. 2022;10: pubmed publisher
Biswas Shivhare S, Lu Q, Sun D, Hou H, Bulmer J, Innes B, et al. Platelet-derived growth factor BB is reduced in endometrial endothelial cells of women with abnormal uterine bleeding-endometrial disorder. Reprod Biomed Online. 2022;45:531-543 pubmed publisher
Kobari L, Auclair M, Piau O, Ferrand N, Zaoui M, Delhommeau F, et al. Circulating cytokines present in multiple myeloma patients inhibit the osteoblastic differentiation of adipose stem cells. Leukemia. 2022;36:540-548 pubmed publisher
Fujiwara Sumiyoshi S, Ueda Y, Fujikawa M, Osaki M, Yamanaka N, Matsumoto T. Mucopolysaccharide polysulfate promotes microvascular stabilization and barrier integrity of dermal microvascular endothelial cells via activation of the angiopoietin-1/Tie2 pathway. J Dermatol Sci. 2021;103:25-32 pubmed publisher
Kim J, Rhim W, Yoo Y, Kim D, Ko K, Heo Y, et al. Defined MSC exosome with high yield and purity to improve regenerative activity. J Tissue Eng. 2021;12:20417314211008626 pubmed publisher
Seki T, Yanaihara N, SHAPIRO J, Saito M, Tabata J, Yokomizo R, et al. Interleukin-6 as an enhancer of anti-angiogenic therapy for ovarian clear cell carcinoma. Sci Rep. 2021;11:7689 pubmed publisher
Hastreiter A, Dos Santos G, Makiyama E, Santos E, Borelli P, Fock R. Effects of protein malnutrition on hematopoietic regulatory activity of bone marrow mesenchymal stem cells. J Nutr Biochem. 2021;93:108626 pubmed publisher
Gao C, Gong Z, Wang D, Huang J, Qian Y, Nie M, et al. Hematoma-derived exosomes of chronic subdural hematoma promote abnormal angiogenesis and inhibit hematoma absorption through miR-144-5p. Aging (Albany NY). 2019;11:12147-12164 pubmed publisher
Scurt F, Menne J, Brandt S, Bernhardt A, Mertens P, Haller H, et al. Systemic Inflammation Precedes Microalbuminuria in Diabetes. Kidney Int Rep. 2019;4:1373-1386 pubmed publisher
van der Kwast R, Woudenberg T, Quax P, Nossent A. MicroRNA-411 and Its 5'-IsomiR Have Distinct Targets and Functions and Are Differentially Regulated in the Vasculature under Ischemia. Mol Ther. 2020;28:157-170 pubmed publisher
Dekker N, van Leeuwen A, van Strien W, Majolee J, Szulcek R, Vonk A, et al. Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels. Crit Care. 2019;23:117 pubmed publisher
Varas Godoy M, Acuña Gallardo S, Venegas Duarte S, Hill C, Caceres Verschae A, Realini O, et al. Angiogenic Properties of Menstrual Stem Cells Are Impaired in Women with a History of Preeclampsia. Stem Cells Int. 2019;2019:1916542 pubmed publisher
Shi Y, Yan H, Yuan J, Zhang H, Huang J, Ni Z, et al. Different patterns of inflammatory and angiogenic factors are associated with peritoneal small solute transport and peritoneal protein clearance in peritoneal dialysis patients. BMC Nephrol. 2018;19:119 pubmed publisher
Moritz F, Schniering J, Distler J, Gay R, Gay S, Distler O, et al. Tie2 as a novel key factor of microangiopathy in systemic sclerosis. Arthritis Res Ther. 2017;19:105 pubmed publisher
Wang K, Liu W, Song Y, Wu X, Zhang Y, Li S, et al. The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration. Lab Invest. 2017;97:971-982 pubmed publisher
Desbourdes L, Javary J, Charbonnier T, Ishac N, Bourgeais J, Iltis A, et al. Alteration Analysis of Bone Marrow Mesenchymal Stromal Cells from De Novo Acute Myeloid Leukemia Patients at Diagnosis. Stem Cells Dev. 2017;26:709-722 pubmed publisher
Tsai Y, Lee C, Chiu Y, Kuo H, Lee S, Hwang S, et al. Angiopoietin-2, Angiopoietin-1 and subclinical cardiovascular disease in Chronic Kidney Disease. Sci Rep. 2016;6:39400 pubmed publisher
Stone O, Carter J, Lin P, Paleolog E, Machado M, Bates D. Differential regulation of blood flow-induced neovascularization and mural cell recruitment by vascular endothelial growth factor and angiopoietin signalling. J Physiol. 2017;595:1575-1591 pubmed publisher
Richter M, Tiede S, Sommer N, Schmidt T, Seeger W, Ghofrani H, et al. Circulating Angiopoietin-1 Is Not a Biomarker of Disease Severity or Prognosis in Pulmonary Hypertension. PLoS ONE. 2016;11:e0165982 pubmed publisher
Hossain M, Shifat R, Johnson D, Bedford M, Gabrusiewicz K, Cortes Santiago N, et al. TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1. Sci Adv. 2016;2:e1501290 pubmed
Chou C, Modo M. Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling. Sci Rep. 2016;6:29029 pubmed publisher
Jongman R, van Klarenbosch J, Molema G, Zijlstra J, de Vries A, van Meurs M. Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass. PLoS ONE. 2015;10:e0136205 pubmed publisher
Nguyen T, Arthur A, Panagopoulos R, Paton S, Hayball J, Zannettino A, et al. EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance. Stem Cells. 2015;33:2838-49 pubmed publisher
Gomes L, Alves Junior E, Rodrigues Jesus C, Nery A, Gasquez Martin T, Fontes C. Angiopoietin-2 and angiopoietin-2/angiopoietin-1 ratio as indicators of potential severity of Plasmodium vivax malaria in patients with thrombocytopenia. PLoS ONE. 2014;9:e109246 pubmed publisher
Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla Herttuala S, et al. Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer. BMC Cancer. 2014;14:696 pubmed publisher
Ghosh C, Mukherjee A, David S, Knaus U, Stearns Kurosawa D, Kurosawa S, et al. Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax. Proc Natl Acad Sci U S A. 2012;109:10024-9 pubmed publisher
Rahbari N, Schmidt T, Falk C, Hinz U, Herber M, Bork U, et al. Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer. BMC Cancer. 2011;11:286 pubmed publisher
Aronis K, Diakopoulos K, Fiorenza C, Chamberland J, Mantzoros C. Leptin administered in physiological or pharmacological doses does not regulate circulating angiogenesis factors in humans. Diabetologia. 2011;54:2358-67 pubmed publisher
Sobrino T, Arias S, Pérez Mato M, Agulla J, Brea D, Rodríguez Yáñez M, et al. Cd34+ progenitor cells likely are involved in the good functional recovery after intracerebral hemorrhage in humans. J Neurosci Res. 2011;89:979-85 pubmed publisher
Ricciuto D, dos Santos C, Hawkes M, Toltl L, Conroy A, Rajwans N, et al. Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med. 2011;39:702-10 pubmed publisher
Boucherat O, Franco Montoya M, Delacourt C, Martinovic J, Masse V, Elie C, et al. Defective angiogenesis in hypoplastic human fetal lungs correlates with nitric oxide synthase deficiency that occurs despite enhanced angiopoietin-2 and VEGF. Am J Physiol Lung Cell Mol Physiol. 2010;298:L849-56 pubmed publisher
Sorensen A, Batchelor T, Zhang W, Chen P, Yeo P, Wang M, et al. A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients. Cancer Res. 2009;69:5296-300 pubmed publisher
Hurliman A, Speroff L, Stouffer R, Patton P, Lee A, Molskness T. Changes in circulating levels and ratios of angiopoietins during pregnancy but not during the menstrual cycle and controlled ovarian stimulation. Fertil Steril. 2010;93:1493-9 pubmed publisher
Kumara H, Shantha Kumara H, Feingold D, Kalady M, Dujovny N, Senagore A, et al. Colorectal resection is associated with persistent proangiogenic plasma protein changes: postoperative plasma stimulates in vitro endothelial cell growth, migration, and invasion. Ann Surg. 2009;249:973-7 pubmed publisher
Labonté L, Li Y, Yang L, Gillingham A, Halpenny M, Giulivi A, et al. Increased plasma EPO and MIP-1 alpha are associated with recruitment of vascular progenitors but not CD34(+) cells in autologous peripheral blood stem cell grafts. Exp Hematol. 2009;37:673-8 pubmed publisher
Serefhanoglu S, Goker H, Buyukasik Y, Turgut M, Sayinalp N, Haznedaroglu I, et al. Changes in vascular endothelial growth factor, angiopoietins, and Tie-2 levels with G-CSF stimulation in healthy donors. Ann Hematol. 2009;88:667-71 pubmed publisher
Shim W, Lim S, Li S, Gu Y, Ong H, Song I, et al. Structural stability of neoangiogenic intramyocardial microvessels supports functional recovery in chronic ischemic myocardium. J Mol Cell Cardiol. 2008;45:70-80 pubmed publisher
Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, et al. Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp Hematol. 2008;36:1035-46 pubmed publisher
Ganter M, Cohen M, Brohi K, Chesebro B, Staudenmayer K, Rahn P, et al. Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?. Ann Surg. 2008;247:320-6 pubmed publisher
Choudhury A, Freestone B, Patel J, Lip G. Relationship of soluble CD40 ligand to vascular endothelial growth factor, angiopoietins, and tissue factor in atrial fibrillation: a link among platelet activation, angiogenesis, and thrombosis?. Chest. 2007;132:1913-9 pubmed
Kanazawa H, Tochino Y, Asai K. Angiopoietin-2 as a contributing factor of exercise-induced bronchoconstriction in asthmatic patients receiving inhaled corticosteroid therapy. J Allergy Clin Immunol. 2008;121:390-5 pubmed
Lee C, Tien H, Hu C, Chou W, Lin L. Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia. Br J Cancer. 2007;97:877-82 pubmed
Anagnostopoulos A, Eleftherakis Papaiakovou V, Kastritis E, Tsionos K, Bamias A, Meletis J, et al. Serum concentrations of angiogenic cytokines in Waldenstrom macroglobulinaemia: the ration of angiopoietin-1 to angiopoietin-2 and angiogenin correlate with disease severity. Br J Haematol. 2007;137:560-8 pubmed
Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, et al. Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts. Stem Cells. 2007;25:1862-71 pubmed
Kanazawa H, Nomura S, Asai K. Roles of angiopoietin-1 and angiopoietin-2 on airway microvascular permeability in asthmatic patients. Chest. 2007;131:1035-41 pubmed
Niedzwiecki S, Stepien T, Kopeć K, Kuzdak K, Komorowski J, Krupinski R, et al. Angiopoietin 1 (Ang-1), angiopoietin 2 (Ang-2) and Tie-2 (a receptor tyrosine kinase) concentrations in peripheral blood of patients with thyroid cancers. Cytokine. 2006;36:291-5 pubmed
Caine G, Ryan P, Lip G, Blann A. Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients. Cancer Lett. 2007;251:296-301 pubmed
Caine G, Stonelake P, Lip G, Blann A. Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer. Cancer Lett. 2007;248:131-6 pubmed

product information

master code :

DANG10

SKU :

DANG10

product name :

Human Angiopoietin-1 Quantikine ELISA Kit

unit size :

1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))

description :

The Human Angiopoietin-1 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human Angiopoietin-1 in cell culture supernates (50 ul), serum (10 ul), edta plasma (10 ul), heparin plasma (10 ul), platelet-poor citrate plasma (10 ul), saliva (25 ul), human milk (25 ul).

target :

Angiopoietin-1

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human Angiopoietin-1

gene symbol :

ANGPT1

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Platelet-poor Citrate Plasma (10 uL), Saliva (25 uL), Human Milk (25 uL)

elisaSensitivity :

10.3 pg/mL

elisaRange :

62.50 - 4000 pg/mL

top caption :

Human Angiopoietin-1 ELISA Calibrator Diluent RD5P (1X) Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human Angiopoietin-1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Angiopoietin-1 in cell culture supernates, serum, plasma, saliva, and human milk. It contains NS0-expressed recombinant human Angiopoietin-1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Angiopoietin-1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Angiopoietin-1.

alt names :

AGP1, AGPT, Ang1, ANG-1, angiopoietin 1, angiopoietin-1, ANGPT1, KIAA0003

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.