This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human IL-17 Quantikine ELISA Kit
catalog :
D1700
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 96
Reference
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Pastwi x144 ska J, Kara x15b K, Sa x142 kowska A, Karwaciak I, Cha x142 a x15b kiewicz K, Wojtczak B, et al. Identification of Corosolic and Oleanolic Acids as Molecules Antagonizing the Human RORγT Nuclear Receptor Using the Calculated Fingerprints of the Molecular Similarity. Int J Mol Sci. 2022;23: pubmed publisher
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Ribeiro I, Pereira Í, Galantini M, Santos D, Teles M, Muniz I, et al. Regular physical activity reduces the effects of inflammaging in diabetic and hypertensive men. Exp Gerontol. 2021;155:111558 pubmed publisher
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Margiotta E, Caldiroli L, Callegari M, Miragoli F, Zanoni F, Armelloni S, et al. Association of Sarcopenia and Gut Microbiota Composition in Older Patients with Advanced Chronic Kidney Disease, Investigation of the Interactions with Uremic Toxins, Inflammation and Oxidative Stress. Toxins (Basel). 2021;13: pubmed publisher
Tu B, Yu B, Wang W, Li J, Yuan F, Zhu J, et al. Inhibition of IL-17 prevents the progression of traumatic heterotopic ossification. J Cell Mol Med. 2021;25:7709-7719 pubmed publisher
Lopes D, Ribeiro I, Santos D, Lima F, Santos A, Souza D, et al. Regular physical activity reduces the proinflammatory response in older women with diabetes and hypertension in the postmenopausal phase. Exp Gerontol. 2021;152:111449 pubmed publisher
Zhang C, Xu C, Gao L, Li X, Zhao C. Porphyromonas gingivalis lipopolysaccharide promotes T-hel per17 cell differentiation by upregulating Delta-like ligand 4 expression on CD14+ monocytes. Peerj. 2021;9:e11094 pubmed publisher
Zhou J, Zhang N, Zhang W, Lu C, Xu F. The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation. Cell Biosci. 2021;11:84 pubmed publisher
Jeong B, Kim J, Jung M, Kang K, Lee Y. Cytokine Profiles of Non-Small Cell Lung Cancer Patients Treated with Concurrent Chemoradiotherapy with Regards to Radiation Pneumonitis Severity. J Clin Med. 2021;10: pubmed publisher
Gałecka M, Bliźniewska Kowalska K, Orzechowska A, Szemraj J, Maes M, Berk M, et al. Inflammatory versus Anti-inflammatory Profiles in Major Depressive Disorders-The Role of IL-17, IL-21, IL-23, IL-35 and Foxp3. J Pers Med. 2021;11: pubmed publisher
Sun J, Jia H, Bao X, Wu Y, Zhu T, Li R, et al. Tumor exosome promotes Th17 cell differentiation by transmitting the lncRNA CRNDE-h in colorectal cancer. Cell Death Dis. 2021;12:123 pubmed publisher
Helmke A, Hüsing A, Gaedcke S, Brauns N, Balzer M, Reinhardt M, et al. Peritoneal dialysate-range hypertonic glucose promotes T-cell IL-17 production that induces mesothelial inflammation. Eur J Immunol. 2021;51:354-367 pubmed publisher
Zychowska M, Batycka Baran A, Baran W. Increased Serum Level and High Tissue Immunoexpression of Interleukin 17 in Cutaneous Lichen Planus: A Novel Therapeutic Target for Recalcitrant Cases?. Dis Markers. 2020;2020:6521274 pubmed publisher
Sałkowska A, Karaś K, Karwaciak I, Walczak Drzewiecka A, Krawczyk M, Sobalska Kwapis M, et al. Identification of Novel Molecular Markers of Human Th17 Cells. Cells. 2020;9: pubmed publisher
Kütük M, Tufan E, Gokcen C, Kilicaslan F, Karadag M, Mutluer T, et al. Cytokine expression profiles in Autism spectrum disorder: A multi-center study from Turkey. Cytokine. 2020;133:155152 pubmed publisher
Auguet T, Bertran L, Binetti J, Aguilar C, Mart xed nez S, Sabench F, et al. Relationship between IL-8 Circulating Levels and TLR2 Hepatic Expression in Women with Morbid Obesity and Nonalcoholic Steatohepatitis. Int J Mol Sci. 2020;21: pubmed publisher
Dozio E, Passeri E, Vianello E, Palmieri S, Eller Vainicher C, Corsi Romanelli M, et al. Circulating IL-17A Levels in Postmenopausal Women with Primary Hyperparathyroidism. Mediators Inflamm. 2020;2020:3417329 pubmed publisher
Liu C, Guo X, Bai S, Zeng G, Wang H. lncRNA CASC2 downregulation participates in rheumatoid arthritis, and CASC2 overexpression promotes the apoptosis of fibroblast‑like synoviocytes by downregulating IL‑17. Mol Med Rep. 2020;21:2131-2137 pubmed publisher
Gabsi A, Heim X, Dlala A, Gati A, Sakhri H, Abidi A, et al. TH17 cells expressing CD146 are significantly increased in patients with Systemic sclerosis. Sci Rep. 2019;9:17721 pubmed publisher
Ribeiro I, Pereira Í, Santos D, Lopes D, Prado A, Calado S, et al. Association between body composition and inflammation: A central role of IL-17 and IL-10 in diabetic and hypertensive elderly women. Exp Gerontol. 2019;127:110734 pubmed publisher
Yu H, Cui S, Mei Y, Li Q, Wu L, Duan S, et al. Mesangial Cells Exhibit Features of Antigen-Presenting Cells and Activate CD4+ T Cell Responses. J Immunol Res. 2019;2019:2121849 pubmed publisher
Vettoretti S, Caldiroli L, Armelloni S, Ferrari C, Cesari M, Messa P. Sarcopenia is Associated with Malnutrition but Not with Systemic Inflammation in Older Persons with Advanced CKD. Nutrients. 2019;11: pubmed publisher
Sun J, Zhang W, Chen W, Wang X, Mu X. Effects of early enteral nutrition on Th17/Treg cells and IL-23/IL-17 in septic patients. World J Gastroenterol. 2019;25:2799-2808 pubmed publisher
Muñoz D, Yannone S, Daemen A, Sun Y, Vakar Lopez F, Kawahara M, et al. Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging. JCI Insight. 2019;5: pubmed publisher
Huang T, Wang J, Zhou Y, Zhao Y, Hang D, Cao Y. LncRNA CASC2 is up-regulated in osteoarthritis and participates in the regulation of IL-17 expression and chondrocyte proliferation and apoptosis. Biosci Rep. 2019;39: pubmed publisher
Clayton S, Cauble E, Kumar A, Patil N, Ledford D, Kolliputi N, et al. Plasma levels of TNF-α, IL-6, IFN-γ, IL-12, IL-17, IL-22, and IL-23 in achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD). BMC Gastroenterol. 2019;19:28 pubmed publisher
Karaś K, Sałkowska A, Sobalska Kwapis M, Walczak Drzewiecka A, Strapagiel D, Dastych J, et al. Digoxin, an Overlooked Agonist of RORγ/RORγT. Front Pharmacol. 2018;9:1460 pubmed publisher
Anzalone G, Albano G, Montalbano A, Riccobono L, Bonanno A, Gagliardo R, et al. IL-17A-associated IKK-α signaling induced TSLP production in epithelial cells of COPD patients. Exp Mol Med. 2018;50:131 pubmed publisher
Wang J, Wu G, Manick B, Hernandez V, Renelt M, Erickson C, et al. VSIG-3 as a ligand of VISTA inhibits human T-cell function. Immunology. 2019;156:74-85 pubmed publisher
Qian L. Decreased interleukin-11 levels in the semen of infertile males. Cytokine. 2018;108:57-59 pubmed publisher
Liu Y, Zhao Q, Yin Y, McNutt M, Zhang T, Cao Y. Serum levels of IL-17 are elevated in patients with acute gouty arthritis. Biochem Biophys Res Commun. 2018;497:897-902 pubmed publisher
Arts R, Moorlag S, Novakovic B, Li Y, Wang S, Oosting M, et al. BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity. Cell Host Microbe. 2018;23:89-100.e5 pubmed publisher
Kuca Warnawin E, Kurowska W, Prochorec Sobieszek M, Radzikowska A, Burakowski T, Skalska U, et al. Rheumatoid arthritis bone marrow environment supports Th17 response. Arthritis Res Ther. 2017;19:274 pubmed publisher
Bughani U, Saha A, Kuriakose A, Nair R, Sadashivarao R, Venkataraman R, et al. T cell activation and differentiation is modulated by a CD6 domain 1 antibody Itolizumab. PLoS ONE. 2017;12:e0180088 pubmed publisher
Meng Z, Zhang Y, Wei Z, Liu P, Kang J, Zhang Y, et al. High serum resistin associates with intrahepatic inflammation and necrosis: an index of disease severity for patients with chronic HBV infection. BMC Gastroenterol. 2017;17:6 pubmed publisher
Ji Y, Mittal S, Hwang H, Chang E, Lee J, Seo Y, et al. Lacrimal gland-derived IL-22 regulates IL-17-mediated ocular mucosal inflammation. Mucosal Immunol. 2017;10:1202-1210 pubmed publisher
Matusiak Ł, Szczęch J, Bieniek A, Nowicka Suszko D, Szepietowski J. Increased interleukin (IL)-17 serum levels in patients with hidradenitis suppurativa: Implications for treatment with anti-IL-17 agents. J Am Acad Dermatol. 2017;76:670-675 pubmed publisher
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Ratajewski M, Walczak Drzewiecka A, Gorzkiewicz M, Sałkowska A, Dastych J. Expression of human gene coding ROR?T receptor depends on the Sp2 transcription factor. J Leukoc Biol. 2016;100:1213-1223 pubmed
Li W, Liu H. CCL20-CCR6 Cytokine Network Facilitate Treg Activity in Advanced Grades and Metastatic Variants of Hepatocellular Carcinoma. Scand J Immunol. 2016;83:33-7 pubmed publisher
Zhao R, Chen N, Zhou X, Miao P, Hu C, Qian L, et al. Exogenous IFN-beta regulates the RANKL-c-Fos-IFN-beta signaling pathway in the collagen antibody-induced arthritis model. J Transl Med. 2014;12:330 pubmed publisher
Chou C, Lin F, Tsai H, Chang S. The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia. BMC Pulm Med. 2014;14:182 pubmed publisher
Schiavoni I, Fedele G, Quattrini A, Bianco M, Schnoeller C, Openshaw P, et al. Live attenuated B. pertussis BPZE1 rescues the immune functions of Respiratory Syncytial virus infected human dendritic cells by promoting Th1/Th17 responses. PLoS ONE. 2014;9:e100166 pubmed publisher
Wu W, Jin M, Wang Y, Liu B, Shen D, Chen P, et al. Overexpression of IL-17RC associated with ocular sarcoidosis. J Transl Med. 2014;12:152 pubmed publisher
Ballantine L, Ong J, Midgley A, Watson L, Flanagan B, Beresford M. The pro-inflammatory potential of T cells in juvenile-onset systemic lupus erythematosus. Pediatr Rheumatol Online J. 2014;12:4 pubmed publisher
Biancheri P, Di Sabatino A, Ammoscato F, Facciotti F, Caprioli F, Curciarello R, et al. Absence of a role for interleukin-13 in inflammatory bowel disease. Eur J Immunol. 2014;44:370-85 pubmed publisher
Kleinnijenhuis J, Quintin J, Preijers F, Benn C, Joosten L, Jacobs C, et al. Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity. J Innate Immun. 2014;6:152-8 pubmed publisher
Vincenzi F, Corciulo C, Targa M, Merighi S, Gessi S, Casetta I, et al. Multiple sclerosis lymphocytes upregulate A2A adenosine receptors that are antiinflammatory when stimulated. Eur J Immunol. 2013;43:2206-16 pubmed publisher
Zheng M, Zhang Z, Bemis K, Belch A, Pilarski L, Shively J, et al. The systemic cytokine environment is permanently altered in multiple myeloma. PLoS ONE. 2013;8:e58504 pubmed publisher
Al Ayadhi L, Mostafa G. Elevated serum levels of interleukin-17A in children with autism. J Neuroinflammation. 2012;9:158 pubmed publisher
Miyagaki T, Sugaya M, Suga H, Kamata M, Ohmatsu H, Fujita H, et al. IL-22, but not IL-17, dominant environment in cutaneous T-cell lymphoma. Clin Cancer Res. 2011;17:7529-38 pubmed publisher
Pandya A, Al Jaderi Z, Høglund R, Holmøy T, Harbo H, Norgauer J, et al. Identification of human NK17/NK1 cells. PLoS ONE. 2011;6:e26780 pubmed publisher
Lee N, Wong C, Chan P, Chan M, Wong R, Lun S, et al. Cytokine response patterns in severe pandemic 2009 H1N1 and seasonal influenza among hospitalized adults. PLoS ONE. 2011;6:e26050 pubmed publisher
Liu B, Wei L, Meyerle C, Tuo J, Sen H, Li Z, et al. Complement component C5a promotes expression of IL-22 and IL-17 from human T cells and its implication in age-related macular degeneration. J Transl Med. 2011;9:1-12 pubmed publisher
Nakajima H, Nakajima K, Tarutani M, Morishige R, Sano S. Kinetics of circulating Th17 cytokines and adipokines in psoriasis patients. Arch Dermatol Res. 2011;303:451-5 pubmed publisher
Fridman J, Scherle P, Collins R, Burn T, Neilan C, Hertel D, et al. Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammation. J Invest Dermatol. 2011;131:1838-44 pubmed publisher
Jun A, Cope L, Speck C, Feng X, Lee S, Meng H, et al. Subnormal cytokine profile in the tear fluid of keratoconus patients. PLoS ONE. 2011;6:e16437 pubmed publisher
Bachert C, Zhang N, Holtappels G, De Lobel L, Van Cauwenberge P, Liu S, et al. Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma. J Allergy Clin Immunol. 2010;126:962-8, 968.e1-6 pubmed publisher
Zhang G, Wang J, Kelly J, Gu G, Hou J, Zhou Y, et al. B7-H3 augments the inflammatory response and is associated with human sepsis. J Immunol. 2010;185:3677-84 pubmed publisher
Doe C, Bafadhel M, Siddiqui S, Desai D, Mistry V, Rugman P, et al. Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD. Chest. 2010;138:1140-7 pubmed publisher
Bakker G, van Erk M, Pellis L, Wopereis S, Rubingh C, Cnubben N, et al. An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach. Am J Clin Nutr. 2010;91:1044-59 pubmed publisher
Xu G, Zhang L, Wang D, Xu R, Liu Z, Han D, et al. Opposing roles of IL-17A and IL-25 in the regulation of TSLP production in human nasal epithelial cells. Allergy. 2010;65:581-9 pubmed publisher
Lee W, Kang S, Choi J, Lee S, Shah K, Eynon E, et al. Regulating human Th17 cells via differential expression of IL-1 receptor. Blood. 2010;115:530-40 pubmed publisher
Sadeghi M, Daniel V, Schnitzler P, Lahdou I, Naujokat C, Zeier M, et al. Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruria. Transplantation. 2009;88:1109-16 pubmed publisher
Wolk K, Witte E, Warszawska K, Schulze Tanzil G, Witte K, Philipp S, et al. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur J Immunol. 2009;39:3570-81 pubmed publisher
Murakami Y, Akahoshi T, Aoki N, Toyomoto M, Miyasaka N, Kohsaka H. Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis. Arthritis Rheum. 2009;60:1615-23 pubmed publisher
Boniface K, Bak Jensen K, Li Y, Blumenschein W, McGeachy M, McClanahan T, et al. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J Exp Med. 2009;206:535-48 pubmed publisher
Shahrara S, Pickens S, Dorfleutner A, Pope R. IL-17 induces monocyte migration in rheumatoid arthritis. J Immunol. 2009;182:3884-91 pubmed publisher
Ciprandi G, De Amici M, Murdaca G, Fenoglio D, Ricciardolo F, Marseglia G, et al. Serum interleukin-17 levels are related to clinical severity in allergic rhinitis. Allergy. 2009;64:1375-8 pubmed publisher
Patel K, Murphy R, White M, Gasparro D, Kelleher D, Ryan T, et al. Interleukin 17: an unlikely marker of acute coronary syndrome?. Atherosclerosis. 2009;205:33-4 pubmed publisher
Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, et al. IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. J Allergy Clin Immunol. 2009;123:59-66.e4 pubmed publisher
Wendling D, Cedoz J, Racadot E. Serum levels of MMP-3 and cathepsin K in patients with ankylosing spondylitis: effect of TNFalpha antagonist therapy. Joint Bone Spine. 2008;75:559-62 pubmed publisher
Jandus C, Bioley G, Rivals J, Dudler J, Speiser D, Romero P. Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides. Arthritis Rheum. 2008;58:2307-17 pubmed publisher
Pene J, Chevalier S, Preisser L, Venereau E, Guilleux M, Ghannam S, et al. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J Immunol. 2008;180:7423-30 pubmed
Zhou M, Yang B, Ma R, Wu C. Memory Th-17 cells specific for C. albicans are persistent in human peripheral blood. Immunol Lett. 2008;118:72-81 pubmed publisher
Schmechel S, Konrad A, Diegelmann J, Glas J, Wetzke M, Paschos E, et al. Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status. Inflamm Bowel Dis. 2008;14:204-12 pubmed
Rao D, Tracey K, Pober J. IL-1alpha and IL-1beta are endogenous mediators linking cell injury to the adaptive alloimmune response. J Immunol. 2007;179:6536-46 pubmed
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Vaknin Dembinsky A, Balashov K, Weiner H. IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol. 2006;176:7768-74 pubmed
Vernal R, Dutzan N, Chaparro A, Puente J, Antonieta Valenzuela M, Gamonal J. Levels of interleukin-17 in gingival crevicular fluid and in supernatants of cellular cultures of gingival tissue from patients with chronic periodontitis. J Clin Periodontol. 2005;32:383-9 pubmed
Hamzaoui K, Hamzaoui A, Guemira F, Bessioud M, Hamza M, Ayed K. Cytokine profile in Behçet's disease patients. Relationship with disease activity. Scand J Rheumatol. 2002;31:205-10 pubmed
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product information
master code :
D1700
SKU :
D1700
product name :
Human IL-17 Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Human IL-17 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human IL-17/IL-17A in cell culture supernates (100 ul), serum (100 ul), edta plasma (100 ul), heparin plasma (100 ul), citrate plasma (100 ul).
target :
IL-17/IL-17A
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human IL-17
gene symbol :
IL17A
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (100 uL), Serum (100 uL), EDTA Plasma (100 uL), Heparin Plasma (100 uL), Citrate Plasma (100 uL)
elisaSensitivity :
15 pg/mL
elisaRange :
31.20 - 2000 pg/mL
top caption :
Human IL-17/IL-17A ELISA Cell Culture Supernate Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human IL-17 Immunoassay is a 4.5 hour solid phase ELISA designed to measure human IL-17 in cell culture supernates, serum, and plasma. It contains E. coli -expressed recombinant human IL-17 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant human IL-17 accurately. Results obtained using natural human IL-17 showed linear curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-17.
alt names :
CTLA8, CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.