Human IL-11 Quantikine ELISA Kit | R&D Systems D1100 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human IL-11 Quantikine ELISA Kit

catalog :

D1100

quantity :

1 Kit

price :

655 USD

citations: 32

Reference
Wang S, Wang P, Zhang M, Song X, Wei L, Ma X, et al. Blocking GP130 binding in interleukin-11 through site-specific PEGylation attenuates bleomycin-induced pulmonary fibrosis in mice. Int J Pharm. 2024;667:124916 pubmed publisher
Widjaja A, Lim W, Viswanathan S, Chothani S, Corden B, Dasan C, et al. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature. 2024;632:157-165 pubmed publisher
Widjaja A, Viswanathan S, Shekeran S, Adami E, Lim W, Chothani S, et al. Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease. Nat Commun. 2022;13:7497 pubmed publisher
Luo Q, Liu J, Fu Q, Zhang X, Yu P, Liu P, et al. Identifying cancer cell-secreted proteins that activate cancer-associated fibroblasts as prognostic factors for patients with pancreatic cancer. J Cell Mol Med. 2022;26:5657-5669 pubmed publisher
Gallo A, Cuscino N, Contino F, Bulati M, Pampalone M, Amico G, et al. Changes in the Transcriptome Profiles of Human Amnion-Derived Mesenchymal Stromal/Stem Cells Induced by Three-Dimensional Culture: A Potential Priming Strategy to Improve Their Properties. Int J Mol Sci. 2022;23: pubmed publisher
Widjaja A, Viswanathan S, Jinrui D, Singh B, Tan J, Wei Ting J, et al. Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts. Front Mol Biosci. 2021;8:740650 pubmed publisher
Hastreiter A, Dos Santos G, Makiyama E, Santos E, Borelli P, Fock R. Effects of protein malnutrition on hematopoietic regulatory activity of bone marrow mesenchymal stem cells. J Nutr Biochem. 2021;93:108626 pubmed publisher
Panahipour L, Omerbasic A, Nasirzade J, Gruber R. TGF-β Activity of a Demineralized Bone Matrix. Int J Mol Sci. 2021;22: pubmed publisher
Dong J, Viswanathan S, Adami E, Singh B, Chothani S, Ng B, et al. Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH. Nat Commun. 2021;12:66 pubmed publisher
Gamage A, Tan K, Chan W, Liu J, Tan C, Ong Y, et al. Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. PLoS Pathog. 2020;16:e1009130 pubmed publisher
Tylicka M, Matuszczak E, Hermanowicz A, D x119 bek W, Karpi x144 ska M, Kami x144 ska J, et al. BDNF and IL-8, But Not UCHL-1 and IL-11, Are Markers of Brain Injury in Children Caused by Mild Head Trauma. Brain Sci. 2020;10: pubmed publisher
Agulló Ortuño M, Gómez Martín O, Ponce S, Iglesias L, Ojeda L, Ferrer I, et al. Blood Predictive Biomarkers for Patients With Non-small-cell Lung Cancer Associated With Clinical Response to Nivolumab. Clin Lung Cancer. 2020;21:75-85 pubmed publisher
Chen Z, Chen X, Xie R, Huang M, Dong W, Han J, et al. DANCR Promotes Metastasis and Proliferation in Bladder Cancer Cells by Enhancing IL-11-STAT3 Signaling and CCND1 Expression. Mol Ther. 2019;27:326-341 pubmed publisher
Terawaki K, Kashiwase Y, Uzu M, Nonaka M, Sawada Y, Miyano K, et al. Leukemia inhibitory factor via the Toll-like receptor 5 signaling pathway involves aggravation of cachexia induced by human gastric cancer-derived 85As2 cells in rats. Oncotarget. 2018;9:34748-34764 pubmed publisher
Qian L. Decreased interleukin-11 levels in the semen of infertile males. Cytokine. 2018;108:57-59 pubmed publisher
Lewis V, Devarajan E, Card Vila M, Thomas D, Kleinerman E, Marchi S, et al. BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translation. Proc Natl Acad Sci U S A. 2017;114:8065-8070 pubmed publisher
Onnis B, Fer N, Rapisarda A, Perez V, Melillo G. Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cells. J Clin Invest. 2013;123:1615-29 pubmed publisher
Rufo A, Del Fattore A, Capulli M, Carvello F, De Pasquale L, Ferrari S, et al. Mechanisms inducing low bone density in Duchenne muscular dystrophy in mice and humans. J Bone Miner Res. 2011;26:1891-903 pubmed publisher
Jung Y, Ahn H, Kim D, Hwang Y, Ho S, Kim J, et al. Improvement of biological and pharmacokinetic features of human interleukin-11 by site-directed mutagenesis. Biochem Biophys Res Commun. 2011;405:399-404 pubmed publisher
Yang L, Wang L, Zhao C, Zhu X, Hou Y, Jun P, et al. Contributions of TRAIL-mediated megakaryocyte apoptosis to impaired megakaryocyte and platelet production in immune thrombocytopenia. Blood. 2010;116:4307-16 pubmed publisher
Liem Moolenaar M, Cerneus D, Molloy C, End D, Brown K, de Kam M, et al. Pharmacodynamics and pharmacokinetics of the novel thrombopoietin mimetic peptide RWJ-800088 in humans. Clin Pharmacol Ther. 2008;84:481-7 pubmed
Bronte Tinkew D, Terebiznik M, Franco A, Ang M, Ahn D, Mimuro H, et al. Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo. Cancer Res. 2009;69:632-9 pubmed publisher
Zdzisinska B, Bojarska Junak A, Dmoszynska A, Kandefer Szerszen M. Abnormal cytokine production by bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells. Arch Immunol Ther Exp (Warsz). 2008;56:207-21 pubmed publisher
Siddappa R, Martens A, Doorn J, Leusink A, Olivo C, Licht R, et al. cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo. Proc Natl Acad Sci U S A. 2008;105:7281-6 pubmed publisher
Zhang Y, Taveggia C, MELENDEZ VASQUEZ C, Einheber S, Raine C, Salzer J, et al. Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation. J Neurosci. 2006;26:12174-85 pubmed
Vergne Salle P, Leger D, Bertin P, Treves R, Beneytout J, Liagre B. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes. Cytokine. 2005;31:335-48 pubmed
Chung H, Kim W, Kim J, Choi E, Lee J, Lee G, et al. Relationship between atopic status and nasal interleukin 10 and 11 levels in infants with respiratory syncytial virus bronchiolitis. Ann Allergy Asthma Immunol. 2005;94:267-72 pubmed
Hirota H, Izumi M, Hamaguchi T, Sugiyama S, Murakami E, Kunisada K, et al. Circulating interleukin-6 family cytokines and their receptors in patients with congestive heart failure. Heart Vessels. 2004;19:237-41 pubmed
López Karpovitch X, Barrales Benitez O, Flores M, Piedras J. Effect of azacytidine in the release of leukemia inhibitory factor, oncostatin m, interleukin (IL)-6, and IL-11 by mononuclear cells of patients with refractory anemia. Cytokine. 2002;20:154-62 pubmed
Dimitriadis E, Robb L, Salamonsen L. Interleukin 11 advances progesterone-induced decidualization of human endometrial stromal cells. Mol Hum Reprod. 2002;8:636-43 pubmed
Carstanjen D, Regenfus M, Muller C, Salama A. Interleukin-6 is a major effector molecule of short-term G-CSF treatment inducing bone metabolism and an acute-phase response. Exp Hematol. 2001;29:812-21 pubmed
Curti A, Ratta M, Corinti S, Girolomoni G, Ricci F, Tazzari P, et al. Interleukin-11 induces Th2 polarization of human CD4(+) T cells. Blood. 2001;97:2758-63 pubmed

product information

master code :

D1100

SKU :

D1100

product name :

Human IL-11 Quantikine ELISA Kit

unit size :

1 Kit

description :

The Human IL-11 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human IL-11 in cell culture supernates (10 ul), serum (100 ul), edta plasma (100 ul), heparin plasma (100 ul), citrate plasma (100 ul).

target :

IL-11

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human IL-11

gene symbol :

IL11

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours or 5 hours

elisaSampleTypes :

Cell Culture Supernates (10 uL), Serum (100 uL), EDTA Plasma (100 uL), Heparin Plasma (100 uL), Citrate Plasma (100 uL)

elisaSensitivity :

8 pg/mL

elisaRange :

15.60 - 1000 pg/mL (Cell Culture Supernates), 31.20 - 2000 pg/mL (Serum, Heparin Plasma, Citrate Plasma, EDTA Plasma)

top caption :

Human IL-11 ELISA Cell Culture Supernate Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human IL-11 Immunoassay is a 4.5-5.0 hour, solid-phase ELISA designed to measure IL-11 in cell culture supernates, serum, or plasma. It contains Sf 21-expressed recombinant human IL-11 and antibodies raised against recombinant human IL-11. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural human IL-11 showed dose curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural IL-11.

alt names :

Adipogenesis inhibitory factor, AGIF, AGIFoprelvekin, IL11, IL-11Oprelvekin, interleukin 11, interleukin-11, Oprelvekin

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.