Human IL-18/IL-1F4 Biotinylated Antibody | R&D Systems D045-6 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-18/IL-1F4 Biotinylated Antibody

catalog :

D045-6

quantity :

50 uL

price :

519 USD

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

159-12B

reactivity :

human

application :

ELISA

more info or order :

R&D Systems product webpage

citations: 11

Reference
Menachem A, Alteber Z, Cojocaru G, Fridman Kfir T, Blat D, Leiderman O, et al. Unleashing Natural IL18 Activity Using an Anti-IL18BP Blocker Induces Potent Immune Stimulation and Antitumor Effects. Cancer Immunol Res. 2024;12:687-703 pubmed publisher
Gavrilin M, Prather E, Vompe A, McAndrew C, Wewers M. cAbl Kinase Regulates Inflammasome Activation and Pyroptosis via ASC Phosphorylation. J Immunol. 2021;206:1329-1336 pubmed publisher
Nuñez S, Ziblat A, Secchiari F, Torres N, Sierra J, Raffo Iraolagoitia X, et al. Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-? and Engagement of CD85j. J Immunol. 2018;200:1008-1015 pubmed publisher
Briend E, Ferguson G, Mori M, Damera G, Stephenson K, Karp N, et al. IL-18 associated with lung lymphoid aggregates drives IFN? production in severe COPD. Respir Res. 2017;18:159 pubmed publisher
Scott L, Bryant A, Rees A, Down B, Jones R, Thornton C. Production and regulation of interleukin-1 family cytokines at the materno-fetal interface. Cytokine. 2017;99:194-202 pubmed publisher
Spallanzani R, Torres N, Avila D, Ziblat A, Iraolagoitia X, Rossi L, et al. Regulatory Dendritic Cells Restrain NK Cell IFN-Î³ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors. J Immunol. 2015;195:2141-8 pubmed publisher
Jitprasertwong P, Jaedicke K, Nile C, Preshaw P, Taylor J. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1β, from human monocytes via activation of caspase-1. Cytokine. 2014;65:222-30 pubmed publisher
Hu H, Kwun J, Aizenstein B, Knechtle S. Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation. 2009;87:1814-20 pubmed publisher
Madsen E, Bruun J, Skogstrand K, Hougaard D, Christiansen T, Richelsen B. Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects. Metabolism. 2009;58:946-53 pubmed publisher
Gonzalez R, Seurynck Servoss S, Crowley S, Brown M, Omenn G, Hayes D, et al. Development and validation of sandwich ELISA microarrays with minimal assay interference. J Proteome Res. 2008;7:2406-14 pubmed publisher
Pfleger C, Schloot N, ter Veld F. Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays. J Immunol Methods. 2008;329:214-8 pubmed

product information

brand :

R&D Systems

master code :

D045-6

SKU :

D045-6

product name :

Human IL-18/IL-1F4 Biotinylated Antibody

unit size :

50 uL

seo description :

The Human IL-18/IL-1F4 Biotinylated Antibody from R&D Systems is a rat monoclonal antibody to IL-18/IL-1F4. This antibody reacts with human. The Human IL-18/IL-1F4 Biotinylated Antibody has been validated for the following applications: ELISA Detection,Antibody Array Development,ELISA Development (Capture),ELISA Development (Detection),ELISA Microarray Development,Luminex Development,ELISA Detection (Matched Antibody Pair).

target :

IL-18/IL-1F4

category :

Primary Antibodies

buffer :

25 ╡g IgG in 50 ╡L volume of PBS containing 1% BSA and 0.09% sodium azide

clonality :

Monoclonal

clone :

159-12B

conjugate :

Biotin

dilution :

ELISA Detection (Matched Antibody Pair) 0.5-2.0 ug/mL

host :

Rat

immunogen :

Human IL-18/IL-1F4

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

This antibody reacts with human IL-18 on ELISA.

gene symbol :

IL18

applications :

ELISA Detection (Matched Antibody Pair),Antibody Array Development,ELISA Development (Capture),ELISA Development (Detection),ELISA Microarray Development,Luminex Development,ELISA Detection

USD :

519 USD

alt names :

Iboctadekin, IFN-gamma-inducing factor, IGIF, IGIFIL-1 gamma, IL18, IL-18MGC12320, IL-1F4, IL1F4iboctadekin, IL-1g, Interferon gamma-inducing factor, interleukin 18 (interferon-gamma-inducing factor), Interleukin-1 gamma, interleukin-18

storage :

This antibody solution is stable for one year from the date of purchase when stored at 4░C.

more info or order :

R&D Systems product webpage