Human IL-18/IL-1F4 Antibody | R&D Systems D044-3 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-18/IL-1F4 Antibody

catalog :

D044-3

quantity :

100 ug

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

125-2H

reactivity :

human

application :

ELISA, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 27

Reference
Mysore V, Cullere X, Settles M, Ji X, Kattan M, Desjardins M, et al. Protective heterologous T cell immunity in COVID-19 induced by the trivalent MMR and Tdap vaccine antigens. Med (N Y). 2021;2:1050-1071.e7 pubmed publisher
Gavrilin M, Prather E, Vompe A, McAndrew C, Wewers M. cAbl Kinase Regulates Inflammasome Activation and Pyroptosis via ASC Phosphorylation. J Immunol. 2021;206:1329-1336 pubmed publisher
Flament H, Rouland M, Beaudoin L, Toubal A, Bertrand L, Lebourgeois S, et al. Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity. Nat Immunol. 2021;22:322-335 pubmed publisher
Ashander L, Lie S, Ma Y, Rochet E, Washington J, Furtado J, et al. Neutrophil Activities in Human Ocular Toxoplasmosis: An In Vitro Study With Human Cells. Invest Ophthalmol Vis Sci. 2019;60:4652-4660 pubmed publisher
Suliman S, Murphy M, Musvosvi M, Gela A, Meermeier E, Geldenhuys H, et al. MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria. J Immunol. 2019;203:2917-2927 pubmed publisher
Magnotti F, Lefeuvre L, Benezech S, Malsot T, Waeckel L, Martin A, et al. Pyrin dephosphorylation is sufficient to trigger inflammasome activation in familial Mediterranean fever patients. EMBO Mol Med. 2019;11:e10547 pubmed publisher
Zhang X, He D, Gao S, Wei Y, Wang L. Aspergillus fumigatus enhances human NK cell activity by regulating M1 macrophage polarization. Mol Med Rep. 2019;20:1241-1249 pubmed publisher
Nuñez S, Ziblat A, Secchiari F, Torres N, Sierra J, Raffo Iraolagoitia X, et al. Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-? and Engagement of CD85j. J Immunol. 2018;200:1008-1015 pubmed publisher
Briend E, Ferguson G, Mori M, Damera G, Stephenson K, Karp N, et al. IL-18 associated with lung lymphoid aggregates drives IFN? production in severe COPD. Respir Res. 2017;18:159 pubmed publisher
Scott L, Bryant A, Rees A, Down B, Jones R, Thornton C. Production and regulation of interleukin-1 family cytokines at the materno-fetal interface. Cytokine. 2017;99:194-202 pubmed publisher
Liu J, Song G, Lin X, Pang X, Meng T. Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells. Exp Ther Med. 2017;13:1447-1455 pubmed publisher
Jiang J, Chen X, An H, Yang B, Zhang F, Cheng X. Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling. Sci Rep. 2016;6:32320 pubmed publisher
Suliman S, Geldenhuys H, Johnson J, Hughes J, Smit E, Murphy M, et al. Bacillus Calmette-Guérin (BCG) Revaccination of Adults with Latent Mycobacterium tuberculosis Infection Induces Long-Lived BCG-Reactive NK Cell Responses. J Immunol. 2016;197:1100-1110 pubmed publisher
Goodier M, Rodríguez Galán A, Lusa C, Nielsen C, Darboe A, Moldoveanu A, et al. Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection. J Immunol. 2016;197:313-25 pubmed publisher
Spallanzani R, Torres N, Avila D, Ziblat A, Iraolagoitia X, Rossi L, et al. Regulatory Dendritic Cells Restrain NK Cell IFN-Î³ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors. J Immunol. 2015;195:2141-8 pubmed publisher
Tsai C, Liong K, Gunalan M, Li N, Lim D, Fisher D, et al. Type I IFNs and IL-18 regulate the antiviral response of primary human Î³Î´ T cells against dendritic cells infected with Dengue virus. J Immunol. 2015;194:3890-900 pubmed publisher
Hedl M, Zheng S, Abraham C. The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways. J Immunol. 2014;192:5924-32 pubmed publisher
Jitprasertwong P, Jaedicke K, Nile C, Preshaw P, Taylor J. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1β, from human monocytes via activation of caspase-1. Cytokine. 2014;65:222-30 pubmed publisher
Valente A, Yoshida T, Izadpanah R, Delafontaine P, Siebenlist U, Chandrasekar B. Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin. Cell Signal. 2013;25:1447-56 pubmed publisher
Venkatesan B, Valente A, Reddy V, Siwik D, Chandrasekar B. Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration. Am J Physiol Heart Circ Physiol. 2009;297:H874-86 pubmed publisher
Hu H, Kwun J, Aizenstein B, Knechtle S. Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation. 2009;87:1814-20 pubmed publisher
Gonzalez R, Seurynck Servoss S, Crowley S, Brown M, Omenn G, Hayes D, et al. Development and validation of sandwich ELISA microarrays with minimal assay interference. J Proteome Res. 2008;7:2406-14 pubmed publisher
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Haas C, Amin M, Allen B, Ruth J, Haines G, Woods J, et al. Inhibition of angiogenesis by interleukin-4 gene therapy in rat adjuvant-induced arthritis. Arthritis Rheum. 2006;54:2402-14 pubmed
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product information

brand :

R&D Systems

master code :

D044-3

SKU :

D044-3

product name :

Human IL-18/IL-1F4 Antibody

unit size :

100 ug

seo description :

The Human IL-18/IL-1F4 Antibody from R&D Systems is a mouse monoclonal antibody to IL-18/IL-1F4. This antibody reacts with human. The Human IL-18/IL-1F4 Antibody has been validated for the following applications: Antibody Array Development,ELISA Development (Capture),ELISA Development (Detection),ELISA Microarray Development,Luminex Development,Flow Cytometry,Neutralization,Functional Assay,Cell Culture,Immunocytochemistry,Immunoprecipitation,ELISA Capture (Matched Antibody Pair).

target :

IL-18/IL-1F4

category :

Primary Antibodies

buffer :

100 ╡g IgG in 100 ╡L volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.

clonality :

Monoclonal

clone :

125-2H

conjugate :

Unconjugated

dilution :

Immunoprecipitation, Neutralization, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL

host :

Mouse

immunogen :

Human IL-18/IL-1F4

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

This antibody reacts with human IL-18 on Immunoprecipitation.

gene symbol :

IL18

applications :

Immunoprecipitation,ELISA Capture (Matched Antibody Pair),Antibody Array Development,ELISA Development (Capture),ELISA Development (Detection),ELISA Microarray Development,Luminex Development,Flow Cytometry,Neutralization,Immunocytochemistry,Functional Assay,Cell Culture

USD :

479 USD

alt names :

Iboctadekin, IFN-gamma-inducing factor, IGIF, IGIFIL-1 gamma, IL18, IL-18MGC12320, IL-1F4, IL1F4iboctadekin, IL-1g, Interferon gamma-inducing factor, interleukin 18 (interferon-gamma-inducing factor), Interleukin-1 gamma, interleukin-18

storage :

This antibody solution is stable for one year from the date of purchase when stored at -20░C.

more info or order :

R&D Systems product webpage