Recombinant Human ACE-2 His-tag Biotinylated Protein, CF | R&D Systems BT933-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human ACE-2 His-tag Biotinylated Protein, CF

catalog :

BT933-020

quantity :

20 ug

price :

564 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Pandey B, Wang Z, Jimenez A, Bhatia E, Jain R, Beach A, et al. A multiadjuvant polysaccharide-amino acid-lipid (PAL) subunit nanovaccine generates robust systemic and lung-specific mucosal immune responses against SARS-CoV-2 in mice. bioRxiv. 2023;: pubmed publisher
Otsubo R, Minamitani T, Kobiyama K, Fujita J, Ito T, Ueno S, et al. Human antibody recognition and neutralization mode on the NTD and RBD domains of SARS-CoV-2 spike protein. Sci Rep. 2022;12:20120 pubmed publisher

image

image 1 :

Recombinant Human ACE-2 His-tag Biotinylated Protein Binding Activity

product information

master code :

BT933

SKU :

BT933-020

product name :

Recombinant Human ACE-2 His-tag Biotinylated Protein, CF

unit size :

20 ug

description :

The Recombinant Human ACE-2 His-tag Biotinylated Protein, CF from R&D Systems is derived from NS0. The Recombinant Human ACE-2 His-tag Biotinylated Protein, CF has been validated for the following applications: Bioactivity, Enzyme Activity.

target :

ACE-2

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl, ZnCl2 and Glycerol.

conjugate :

Biotin

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

100-110 kDa, under reducing conditions

theoretical molecular weight :

85 kDa

details of functionality :

Biotinylated Recombinant Human ACE-2 His-tag (Catalog # BT933) binds Recombinant Viral SARS-CoV-2 S Protein RBD Fc Chimera (Catalog # 10499-CV ) in a functional ELISA. Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH (Catalog # ES007 ). The specific activity is 600 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human ACE-2 His-tag Biotinylated Protein Binding Activity

accessionNumbers :

Q9BYF1.2

applications :

Bioactivity, Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived human ACE-2 protein Gln18-Ser740 with a C-terminal 10-His tag

source short :

NS0

extended description :

Biotinylated via Amines

USD :

564 USD

product details :

Biotinylated via Amines

alt names :

ACE2, ACEH, ACEHangiotensin I converting enzyme 2, ACE-related carboxypeptidase, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, DKFZp434A014, EC 3.4.17, EC 3.4.17.23, Metalloprotease MPROT15

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage