product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human FGF basic/FGF2/bFGF Protein, CF
catalog :
BT-FGFB-020
quantity :
20 ug (also 50 ug, 100 ug, 250 ug, 500 ug, 1 mg)
price :
107 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Ge Y, Cheng Y, Yin T, Peng X, Xiong Z, Wu B, et al. Generation of a human induced pluripotent stem cell line (FDCHi012-A) from a patient with DYRK1A-related intellectual disability syndrome carrying DYRK1A mutation (c.1024G > T). Stem Cell Res. 2024;76:103345 pubmed publisher
Xue H, Gate S, Gentry E, Losert W, Cao K. Development of an accelerated cellular model for early changes in Alzheimer's disease. Sci Rep. 2023;13:18384 pubmed publisher
Johnstone B, Gu D, Lin C, Du J, Woods E. Identification of a fundamental cryoinjury mechanism in MSCs and its mitigation through cell-cycle synchronization prior to freezing. Cryobiology. 2023;113:104592 pubmed publisher
product information
master code :
BT-FGFB
SKU :
BT-FGFB-020
product name :
Recombinant Human FGF basic/FGF2/bFGF Protein, CF
unit size :
20 ug (also 50 ug, 100 ug, 250 ug, 500 ug, 1 mg)
description :
The Recombinant Human FGF basic/FGF2/bFGF Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human FGF basic/FGF2/bFGF Protein, CF has been validated for the following applications: Bioactivity.
target :
FGF basic/FGF2/bFGF
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in HEPES and Sodium Sulfate with Trehalose.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
18 kDa, under reducing conditions.
theoretical molecular weight :
17 kDa
details of functionality :
Measured by its ability to inhibit human FGF-basic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120; Watson, J.B. et al . (1994) J. Clin. Invest. 94 :261. The ED50 for this effect is 0.100-1.00 ng/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_001997.5
applications :
Bioactivity
source long :
E. coli -derived human FGF basic/FGF2/bFGF protein Ala135-Ser288
source short :
E. coli
USD :
107 USD
alt names :
Basic fibroblast growth factor, basic fibroblast growth factor bFGF, bFGF, FGF2, FGF-2, FGFBprostatropin, fibroblast growth factor 2 (basic), HBGF-2, heparin-binding growth factor 2, Prostatropin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.