product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-7 Protein, Animal-Free
catalog :
BT-007-AFL-025
quantity :
25 ug (also 1 mg)
price :
694 USD
more info or order :
citations: 1
Reference
Somasundaram A, Cillo A, Lampenfeld C, Workman C, Kunning S, Oliveri L, et al. Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells. Cancer Immunol Res. 2022;10:885-899 pubmed publisher
image
image 1 :
R&D Systems BT-007-AFL-025 image 1
product information
master code :
BT-007-AFL
SKU :
BT-007-AFL-025
product name :
Recombinant Human IL-7 Protein, Animal-Free
unit size :
25 ug (also 1 mg)
description :
The Recombinant Human IL-7 Protein, Animal-Free from R&D Systems is derived from E. coli. The Recombinant Human IL-7 Protein, Animal-Free has been validated for the following applications: Bioactivity.
target :
IL-7
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
species :
Human
observed molecular weight :
17 kDa, under reducing conditions.
theoretical molecular weight :
17 kDa
details of functionality :
Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). Yokota, T. et al . (1986) Proc. Natl. Acad. Sci. USA 83 :5894. The ED50 for this effect is 0.100-0.500 ng/mL.The specific activity of Recombinant Human IL-7 is 1.00 x 108 units/mg, which is calibrated against the human IL-7 reference standard (NIBSC code: 90/530).
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P13232.1
applications :
Bioactivity
source long :
E. coli -derived human IL-7 protein Asp26-His177, with an N-terminal Met Produced using non-animal reagents in an animal-free laboratory.
source short :
E. coli
extended description :
Intended for preclinical researchers who may transition to GMP IL-7 for their clinical work
USD :
694 USD
product details :
Intended for preclinical researchers who may transition to GMP IL-7 for their clinical work
alt names :
IL7, IL-7interleukin-7, interleukin 7, Lymphopoietin-1, PBGF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.