protein

Recombinant Human IL-2 GMP Protein, CF

BT-002-GMP-050/LQ

50 ug (also 1 mg)

524 USD

BT-002-GMP-050/LQ

Recombinant Human IL-2 GMP Protein, CF

50 ug (also 1 mg)

The Recombinant Human IL-2 GMP Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human IL-2 GMP Protein, CF has been validated for the following applications: Bioactivity.

IL-2

Proteins and Enzymes

Supplied as a 0.2 ╡m filtered solution in Sodium Acetate.

Unconjugated

97%, by SDS-PAGE with quantitative densitometry by Coomassie« Blue Staining. The molecular weight by mass spectrometry is 15521 ▒ 5 Da, and a second 15390 ▒ 5 Da product may be present

13 kDa, under reducing conditions.

15.5 kDa

Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. Gearing, A.J.H. and C.B. Bird (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 295. The ED50 for this effect is 0.0300-0.250 ng/mL. The specific activity of recombinant human IL-2 is 5.00 x 106 IU/mg, which is calibrated against an internal reference standard value assigned against the human IL-2 WHO International Standard (NIBSC code: 86/500).

<0.01 EU per 1 ╡g of the protein by the LAL method.

P60568.1

Bioactivity

E. coli -derived human IL-2 protein Ala21-Thr153 (Cys145Ser), with and without an N-terminal Met Produced using non-animal reagents in an animal-free laboratory. Manufactured and tested under cGMP guidelines.

E. coli

Animal-Free. Contains the Cysteine to Serine substitution found in Proleukin« (aldesleukin)

524 USD

Animal-Free. Contains the Cysteine to Serine substitution found in Proleukin« (aldesleukin)

aldesleukin, IL2, IL-2, IL-2lymphokine, interleukin 2, interleukin-2, involved in regulation of T-cell clonal expansion, Proleukin, T cell growth factor, T-cell growth factor, TCGF

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. A minimum of 6 months when stored at <= -65 ░C as supplied. Refer to lot specific COA for the Use by Date. 1 month, 2 to 8 ░C under sterile conditions after opening. 3 months, <= -20 ░C under sterile conditions after opening.