Recombinant Human IL-2 Protein, Animal-Free | R&D Systems BT-002-AFL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-2 Protein, Animal-Free

catalog :

BT-002-AFL-050

quantity :

50 ug (also 1 mg)

price :

311 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Lv H, Zong Q, Chen C, Lv G, Xiang W, Xing F, et al. TET2-mediated tumor cGAS triggers endothelial STING activation to regulate vasculature remodeling and anti-tumor immunity in liver cancer. Nat Commun. 2024;15:6 pubmed publisher

image

image 1 :

product information

master code :

BT-002-AFL

SKU :

BT-002-AFL-050

product name :

Recombinant Human IL-2 Protein, Animal-Free

unit size :

50 ug (also 1 mg)

description :

The Recombinant Human IL-2 Protein, Animal-Free from R&D Systems is derived from E. coli. The Recombinant Human IL-2 Protein, Animal-Free has been validated for the following applications: Bioactivity.

target :

IL-2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Sodium Acetate with Trehalose.

conjugate :

Unconjugated

species :

Human

observed molecular weight :

13 kDa, under reducing conditions.

theoretical molecular weight :

15.5 kDa

details of functionality :

Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. Gearing, A.J.H. and C.B. Bird (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 295. The ED50 for this effect is 0.0300-0.250 ng/mL. . The specific activity of recombinant human IL-2 is 5.00 x 106 IU/mg, which is calibrated against an internal reference standard value assigned against the human IL-2 WHO International Standard (NIBSC code: 86/500).

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P60568.1

applications :

Bioactivity

source long :

E. coli -derived human IL-2 protein Ala21-Thr153 (Cys145Ser), with and without an N-terminal Met Produced using non-animal reagents in an animal-free laboratory.

source short :

E. coli

extended description :

Contains the cysteine to serine mutation found in Proleukin« (aldesleukin); Intended for preclinical researchers who may transition to GMP IL-2 for their clinical work

USD :

311 USD

product details :

Contains the cysteine to serine mutation found in Proleukin« (aldesleukin); Intended for preclinical researchers who may transition to GMP IL-2 for their clinical work

alt names :

aldesleukin, IL2, IL-2, IL-2lymphokine, interleukin 2, interleukin-2, involved in regulation of T-cell clonal expansion, Proleukin, T cell growth factor, T-cell growth factor, TCGF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage