Human P-Selectin/CD62P Antibody | R&D Systems BBA30 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human P-Selectin/CD62P Antibody

catalog :

BBA30

quantity :

200 ug

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9.00E+01

reactivity :

human

application :

immunohistochemistry, neutralization, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 9

Reference
Hottz E, Martins Gon xe7 alves R, Palhinha L, Azevedo Quintanilha I, de Campos M, Sacramento C, et al. Platelet-monocyte interaction amplifies thromboinflammation through tissue factor signaling in COVID-19. Blood Adv. 2022;6:5085-5099 pubmed publisher
Perico L, Morigi M, Galbusera M, Pezzotta A, Gastoldi S, Imberti B, et al. SARS-CoV-2 Spike Protein 1 Activates Microvascular Endothelial Cells and Complement System Leading to Platelet Aggregation. Front Immunol. 2022;13:827146 pubmed publisher
Li T, Yang Y, Li Y, Wang Z, Ma F, Luo R, et al. Platelets mediate inflammatory monocyte activation by SARS-CoV-2 spike protein. J Clin Invest. 2022;132: pubmed publisher
Mistry H, Ogalde M, Broughton Pipkin F, Escher G, Kurlak L. Maternal, Fetal, and Placental Selectins in Women With Pre-eclampsia; Association With the Renin-Angiotensin-System. Front Med (Lausanne). 2020;7:270 pubmed publisher
Klinger M, Zugmaier G, Nägele V, Goebeler M, Brandl C, Stelljes M, et al. Adhesion of T Cells to Endothelial Cells Facilitates Blinatumomab-Associated Neurologic Adverse Events. Cancer Res. 2020;80:91-101 pubmed publisher
Hottz E, Medeiros de Moraes I, Vieira de Abreu A, de Assis E, Vals de Souza R, Castro Faria Neto H, et al. Platelet activation and apoptosis modulate monocyte inflammatory responses in dengue. J Immunol. 2014;193:1864-72 pubmed publisher
Singh M, Davidson D, Jackson J, Singh V, Silva J, Ramirez S, et al. Characterization of platelet-monocyte complexes in HIV-1-infected individuals: possible role in HIV-associated neuroinflammation. J Immunol. 2014;192:4674-84 pubmed publisher
Prakobphol A, Genbacev O, Gormley M, Kapidzic M, Fisher S. A role for the L-selectin adhesion system in mediating cytotrophoblast emigration from the placenta. Dev Biol. 2006;298:107-17 pubmed
Gao Y, Li N, Fei R, Chen Z, Zheng S, Zeng X. P-Selectin-mediated acute inflammation can be blocked by chemically modified heparin, RO-heparin. Mol Cells. 2005;19:350-5 pubmed

product information

master code :

BBA30

SKU :

BBA30

product name :

Human P-Selectin/CD62P Antibody

unit size :

200 ug

description :

The Human P-Selectin/CD62P Antibody from R&D Systems is a mouse monoclonal antibody to P-Selectin/CD62P. This antibody reacts with human. The Human P-Selectin/CD62P Antibody has been validated for the following applications: Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Adhesion Blockade.

target :

P-Selectin/CD62P

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

clonality :

Monoclonal

clone :

9.00E+01

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant human P-Selectin, Extracellular domain

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

This antibody binds to CHO cells transfected with human P-Selectin but not to CHO cells transfected with either human E-Selectin or human L-Selectin.

gene symbol :

SELP

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

P-Selectin/CD62P antibody in Human Breast Cancer Tissue by Immunohistochemistry (IHC-P).

applications :

Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Adhesion Blockade

USD :

499 USD

alt names :

CD62P, CD62P antigen, FLJ45155, GMP140, GRMP, PADGEM, PADGEMantigen CD62), PSEL, selectin P (granule membrane protein 140kDa, antigen CD62), SELP

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage