product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human E-Selectin/CD62E Antibody
catalog :
BBA26-200
quantity :
200 ug
price :
399 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BBIG-E1
reactivity :
human
application :
western blot, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry
more info or order :
R&D Systems product webpage
citations: 8
Reference
Banka A, Guevara M, Brannon E, Nguyen N, Song S, Cady G, et al. Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation. Nat Commun. 2023;14:2462 pubmed publisher
Clé M, Desmetz C, Barthelemy J, Martin M, Constant O, Maarifi G, et al. Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier. MBio. 2020;11: pubmed publisher
Lam F, Da Q, Guillory B, Cruz M. Recombinant Human Vimentin Binds to P-Selectin and Blocks Neutrophil Capture and Rolling on Platelets and Endothelium. J Immunol. 2018;200:1718-1726 pubmed publisher
Pachón Peña G, Donnelly C, Ruiz Cañada C, Katz A, Fernández Veledo S, Vendrell J, et al. A Glycovariant of Human CD44 is Characteristically Expressed on Human Mesenchymal Stem Cells. Stem Cells. 2017;35:1080-1092 pubmed publisher
Poeter M, Brandherm I, Rossaint J, Rosso G, Shahin V, Skryabin B, et al. Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63. Nat Commun. 2014;5:3738 pubmed publisher
Pezeshkian B, Donnelly C, Tamburo K, Geddes T, Madlambayan G. Leukemia Mediated Endothelial Cell Activation Modulates Leukemia Cell Susceptibility to Chemotherapy through a Positive Feedback Loop Mechanism. PLoS ONE. 2013;8:e60823 pubmed publisher
Fitau J, Boulday G, Coulon F, Quillard T, Charreau B. The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways. J Biol Chem. 2006;281:20148-59 pubmed
Lawson C, Ainsworth M, Yacoub M, Rose M. Ligation of ICAM-1 on endothelial cells leads to expression of VCAM-1 via a nuclear factor-kappaB-independent mechanism. J Immunol. 1999;162:2990-6 pubmed
product information
brand :
R&D Systems
master code :
BBA26
SKU :
BBA26-200
product name :
Human E-Selectin/CD62E Antibody
unit size :
200 ug
seo description :
The Human E-Selectin/CD62E Antibody from R&D Systems is a mouse monoclonal antibody to E-Selectin/CD62E. This antibody reacts with human. The Human E-Selectin/CD62E Antibody has been validated for the following applications: Blocking,Flow Cytometry,Western Blot,Neutralization,Functional Assay,Immunocytochemistry,Immunoprecipitation,Adhesion Blockade,Immunofluorescence,CyTOF-ready.
target :
E-Selectin/CD62E
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
clonality :
Monoclonal
clone :
BBIG-E1
conjugate :
Unconjugated
dilution :
Flow Cytometry 0.25 ug/10^6 cells, Immunoprecipitation, Adhesion Blockade, Immunofluorescence, Immunocytochemistry 8-25 ug/mL, CyTOF-ready
host :
Mouse
immunogen :
Activated HUVEC human umbilical vein endothelial cells
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
This antibody binds to CHO cells transfected with human E-Selectin. It does not bind to COS cells transfected with human PECAM-1, P-Selectin, L-Selectin, VCAM-1, or ICAM-1.
gene symbol :
SELE
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
applications :
Immunoprecipitation,Adhesion Blockade,Immunofluorescence,CyTOF-ready,Blocking,Flow Cytometry,Western Blot,Neutralization,Immunocytochemistry,Functional Assay
USD :
399 USD
alt names :
CD62 antigen-like family member E, CD62E, CD62E antigen, ELAM, ELAM1, ELAM-1, ELAM1E-selectin, endothelial adhesion molecule 1, Endothelial leukocyte adhesion molecule 1, ESEL, LECAM2, leukocyte endothelial cell adhesion molecule 2, Leukocyte-endothelial cell adhesion molecule 2, SELE, selectin E
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.