Human CD44v3 Antibody | R&D Systems BBA11 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD44v3 Antibody

catalog :

BBA11

quantity :

200 ug

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3G5

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 8

Reference
Hofmann L, Ludwig S, Schuler P, Hoffmann T, Brunner C, Theodoraki M. The Potential of CD16 on Plasma-Derived Exosomes as a Liquid Biomarker in Head and Neck Cancer. Int J Mol Sci. 2020;21: pubmed publisher
Theodoraki M, Matsumoto A, Beccard I, Hoffmann T, Whiteside T. CD44v3 protein-carrying tumor-derived exosomes in HNSCC patients' plasma as potential noninvasive biomarkers of disease activity. Oncoimmunology. 2020;9:1747732 pubmed publisher
Tirella A, Kloc Muniak K, Good L, Ridden J, Ashford M, Puri S, et al. CD44 targeted delivery of siRNA by using HA-decorated nanotechnologies for KRAS silencing in cancer treatment. Int J Pharm. 2019;561:114-123 pubmed publisher
Yoo S, Leng L, Kim B, Du X, Tilstam P, Kim K, et al. MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2016;113:E7917-E7926 pubmed
Bailon E, Ugarte Berzal E, Amigo Jiménez I, Van den Steen P, Opdenakker G, Garcia Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed publisher
Shannon Lowe C, Rowe M. Epstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection. PLoS Pathog. 2011;7:e1001338 pubmed publisher
Barbour A, Reeder J, Walsh M, Fawcett J, Antalis T, Gotley D. Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3. Cancer Res. 2003;63:887-92 pubmed
Dingemans K, Ramkema M, Pals S. CD44 is exposed to the extracellular matrix at invasive sites in basal cell carcinomas. Lab Invest. 2002;82:313-22 pubmed

product information

master code :

BBA11

SKU :

BBA11

product name :

Human CD44v3 Antibody

unit size :

200 ug

description :

The Human CD44v3 Antibody from R&D Systems is a mouse monoclonal antibody to CD44. This antibody reacts with human,mouse. The Human CD44v3 Antibody has been validated for the following applications: Immunogold Electron Microscopy,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunoprecipitation,Western Blot,CyTOF-ready.

target :

CD44

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

clonality :

Monoclonal

clone :

3G5

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant human CD44v3-10

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human CD44v3 in Western blots. The specificity of monoclonal antibody clone 3G5 was determined by FACS analysis on a panel of CD44 transfected COS cells, and was deduced to be specific for CD44 protein isoforms containing human variant exon 3 (9).

gene symbol :

CD44

top caption :

CD44 antibody in Human PBMCs by Immunocytochemistry (ICC).

applications :

Immunogold Electron Microscopy,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunoprecipitation,Western Blot,CyTOF-ready

USD :

489 USD

alt names :

CD44, CD44 antigen, CD44 molecule (Indian blood group), CD44R, CDw44, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan sulfate proteoglycan, Hermes antigen, homing function and Indian blood group system, HUTCH-I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU2CD44 antigen (homing function and Indian blood group system), MDU3, MDU3CDW44, MIC4, MIC4MGC10468, MUTCH-I, Pgp1, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage