Human E-Selectin/P-Selectin (CD62E/P) Antibody | R&D Systems BBA1 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human E-Selectin/P-Selectin (CD62E/P) Antibody

catalog :

BBA1

quantity :

100 ug

price :

419 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

BBIG-E6 (13D5)

reactivity :

human, rat

application :

ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 19

Reference
Koshrovski Michael S, Ajamil D, Dey P, Kleiner R, Tevet S, Epshtein Y, et al. Two-in-one nanoparticle platform induces a strong therapeutic effect of targeted therapies in P-selectin-expressing cancers. Sci Adv. 2024;10:eadr4762 pubmed publisher
Kintos D, Salagiannis K, Sgouros A, Nikolaropoulos S, Topouzis S, Fousteris M. Identification of new multi-substituted 1H-pyrazolo[3,4-c]pyridin-7(6H)-ones as soluble guanylyl cyclase (sGC) stimulators with vasoprotective and anti-inflammatory activities. Bioorg Chem. 2024;144:107170 pubmed publisher
Constant O, Maarifi G, Barthelemy J, Martin M, Tinto B, Savini G, et al. Differential effects of Usutu and West Nile viruses on neuroinflammation, immune cell recruitment and blood-brain barrier integrity. Emerg Microbes Infect. 2023;12:2156815 pubmed publisher
Krivitsky A, Pozzi S, Yeini E, Israeli Dangoor S, Zur T, Golan S, et al. Sulfonated Amphiphilic Poly(α)glutamate Amine-A Potential siRNA Nanocarrier for the Treatment of Both Chemo-Sensitive and Chemo-Resistant Glioblastoma Tumors. Pharmaceutics. 2021;13: pubmed publisher
Neufeld L, Yeini E, Reisman N, Shtilerman Y, Ben Shushan D, Pozzi S, et al. Microengineered perfusable 3D-bioprinted glioblastoma model for in vivo mimicry of tumor microenvironment. Sci Adv. 2021;7: pubmed publisher
Yeini E, Ofek P, Pozzi S, Albeck N, Ben Shushan D, Tiram G, et al. P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression. Nat Commun. 2021;12:1912 pubmed publisher
Clé M, Desmetz C, Barthelemy J, Martin M, Constant O, Maarifi G, et al. Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier. MBio. 2020;11: pubmed publisher
Sabol R, Villela V, Denys A, Freeman B, Hartono A, Wise R, et al. Obesity-Altered Adipose Stem Cells Promote Radiation Resistance of Estrogen Receptor Positive Breast Cancer through Paracrine Signaling. Int J Mol Sci. 2020;21: pubmed publisher
Belcher J, Chen C, Nguyen J, Abdulla F, Zhang P, Nguyen H, et al. Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction. PLoS ONE. 2018;13:e0196455 pubmed publisher
Morrogh Bernard H, Foitova I, Yeen Z, Wilkin P, de Martin R, Rárová L, et al. Self-medication by orang-utans (Pongo pygmaeus) using bioactive properties of Dracaena cantleyi. Sci Rep. 2017;7:16653 pubmed publisher
Rouger C, Pagie S, Derbré S, Le Ray A, Richomme P, Charreau B. Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells. PLoS ONE. 2016;11:e0167361 pubmed publisher
Liu Z, Tian R, Li Y, Zhang L, Shao H, Yang C, et al. SDF-1?-induced dual pairs of E-selectin/ligand mediate endothelial progenitor cell homing to critical ischemia. Sci Rep. 2016;6:34416 pubmed publisher
Liu Z, Daftarian P, Kovalski L, Wang B, Tian R, Castilla D, et al. Directing and Potentiating Stem Cell-Mediated Angiogenesis and Tissue Repair by Cell Surface E-Selectin Coating. PLoS ONE. 2016;11:e0154053 pubmed publisher
MacKay J, Hammer D. Stiff substrates enhance monocytic cell capture through E-selectin but not P-selectin. Integr Biol (Camb). 2016;8:62-72 pubmed publisher
JÃ¸rgensen M, BÃ¦k R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed publisher
Roe K, Orillo B, Verma S. West Nile virus-induced cell adhesion molecules on human brain microvascular endothelial cells regulate leukocyte adhesion and modulate permeability of the in vitro blood-brain barrier model. PLoS ONE. 2014;9:e102598 pubmed publisher
Duluc D, Gannevat J, Anguiano E, Zurawski S, Carley M, Boreham M, et al. Functional diversity of human vaginal APC subsets in directing T-cell responses. Mucosal Immunol. 2013;6:626-38 pubmed publisher
Sackmann E, Berthier E, Young E, Shelef M, Wernimont S, Huttenlocher A, et al. Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assays. Blood. 2012;120:e45-53 pubmed publisher
Cunningham D, Dos Santos Cruz G, Fernandez Suarez X, Whittam A, Herring C, Copeman L, et al. Activation of primary porcine endothelial cells induces release of porcine endogenous retroviruses. Transplantation. 2004;77:1071-9 pubmed

product information

master code :

BBA1

SKU :

BBA1

product name :

Human E-Selectin/P-Selectin (CD62E/P) Antibody

unit size :

100 ug

description :

The Human E-Selectin/P-Selectin (CD62E/P) Antibody from R&D Systems is a mouse monoclonal antibody to E-Selectin (CD62E)/P-Selectin (CD62P). This antibody reacts with human,porcine,rat,insect - aedes albopictus (asian tiger mosquito). The Human E-Selectin/P-Selectin (CD62E/P) Antibody has been validated for the following applications: ELISA Capture,Flow Cytometry,Neutralization,Immunohistochemistry,Immunocytochemistry,Immunoprecipitation,Adhesion Blockade,CyTOF-ready.

target :

E-Selectin (CD62E)/P-Selectin (CD62P)

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

clonality :

Monoclonal

clone :

BBIG-E6 (13D5)

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Activated HUVEC human umbilical vein endothelial cells

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Porcine,Rat,Insect - Aedes albopictus (Asian tiger mosquito)

specificity :

Detects human E-Selectin/P-Selectin (CD62E/P). Binds to COS cells transfected with human E-Selectin or human P-Selectin. It does not bind to CHO cells transfected with human ICAM-1, L-Selectin, PECAM-1 or VCAM-1.

top caption :

E-Selectin (CD62E)/P-Selectin (CD62P) antibody in HUVEC Human Cells by Immunocytochemistry (ICC).

applications :

Flow Cytometry,Neutralization,Immunohistochemistry,ELISA Capture,Immunocytochemistry,Immunoprecipitation,Adhesion Blockade,CyTOF-ready

USD :

419 USD

alt names :

CD62E, CD62P, ELAM, ELAM1, ESEL, Eselectin, GMP140, GRMP, LECAM2, PADGEM, PSEL, PSelectin, SELE, SELP

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage