product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CD45 Biotinylated Antibody
catalog :
BAM1430
quantity :
100 ug
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
2D1
reactivity :
human
application :
immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 12
Reference
Guo H, Vuille J, Wittner B, Lachtara E, Hou Y, Lin M, et al. DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs. Cell. 2023;186:2765-2782.e28 pubmed publisher
Ebright R, Zachariah M, Micalizzi D, Wittner B, Niederhoffer K, Nieman L, et al. HIF1A signaling selectively supports proliferation of breast cancer in the brain. Nat Commun. 2020;11:6311 pubmed publisher
Franses J, Philipp J, Missios P, Bhan I, Liu A, Yashaswini C, et al. Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target. Nat Commun. 2020;11:3303 pubmed publisher
Inan H, Kingsley J, Ozen M, Tekin H, Hoerner C, Imae Y, et al. Monitoring Neutropenia for Cancer Patients at the Point of Care. Small Methods. 2017;1: pubmed publisher
Aceto N, Bardia A, Wittner B, Donaldson M, O Keefe R, Engstrom A, et al. AR Expression in Breast Cancer CTCs Associates with Bone Metastases. Mol Cancer Res. 2018;16:720-727 pubmed publisher
Hong X, Sullivan R, Kalinich M, Kwan T, Giobbie Hurder A, Pan S, et al. Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy. Proc Natl Acad Sci U S A. 2018;115:2467-2472 pubmed publisher
Franses J, Basar O, Kadayifci A, Yuksel O, Choz M, Kulkarni A, et al. Improved Detection of Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasms. Oncologist. 2018;23:121-127 pubmed publisher
Zheng Y, Miyamoto D, Wittner B, Sullivan J, Aceto N, Jordan N, et al. Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination. Nat Commun. 2017;8:14344 pubmed publisher
Jordan N, Bardia A, Wittner B, Benes C, Ligorio M, Zheng Y, et al. HER2 expression identifies dynamic functional states within circulating breast cancer cells. Nature. 2016;537:102-106 pubmed publisher
Tseng C, Biancotti J, Berg B, Gate D, Kolar S, Müller S, et al. Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection. PLoS Pathog. 2015;11:e1005292 pubmed publisher
Ting D, Wittner B, Ligorio M, Vincent Jordan N, Shah A, Miyamoto D, et al. Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells. Cell Rep. 2014;8:1905-1918 pubmed publisher
Brownell J, Wagoner J, Lovelace E, Thirstrup D, Mohar I, Smith W, et al. Independent, parallel pathways to CXCL10 induction in HCV-infected hepatocytes. J Hepatol. 2013;59:701-8 pubmed publisher
product information
master code :
BAM1430
SKU :
BAM1430
product name :
Human CD45 Biotinylated Antibody
unit size :
100 ug
description :
The Human CD45 Biotinylated Antibody from R&D Systems is a mouse monoclonal antibody to CD45. This antibody reacts with human. The Human CD45 Biotinylated Antibody has been validated for the following applications: Bioassay,Cell Capture,Flow Cytometry,Neutralization,Cell Selection,Immunohistochemistry-Paraffin,Immunocytochemistry.
target :
CD45
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Monoclonal
clone :
2D1
concentration :
LYOPH
conjugate :
Biotin
host :
Mouse
immunogen :
Human peripheral blood mononuclear cells
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human CD45. This antibody recognizes all isoforms of human CD45.
gene symbol :
PTPRC
top caption :
CD45 antibody in human PBMCs by Immunocytochemistry (ICC).
applications :
Bioassay,Flow Cytometry,Neutralization,Cell Selection,Immunohistochemistry-Paraffin,Immunocytochemistry
USD :
459 USD
alt names :
B220, CD_antigen: CD45, CD45, CD45 antigen, CD45R, EC 3.1.3.48, EC:3.1.3.48, GP180, LCA, L-CA, Leukocyte common antigen, LY5, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, receptor-type tyrosine-protein phosphatase C, T200, T200 glycoprotein, T200 leukocyte common antigen
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.