product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Wnt-5a Biotinylated Antibody
catalog :
BAF645
quantity :
50 ug
price :
529 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
biotin
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 7
Reference
Fane M, Chhabra Y, Alicea G, Maranto D, Douglass S, Webster M, et al. Stromal changes in the aged lung induce an emergence from melanoma dormancy. Nature. 2022;606:396-405 pubmed publisher
Douglass S, Fane M, Sanseviero E, Ecker B, Kugel C, Behera R, et al. Myeloid-Derived Suppressor Cells Are a Major Source of Wnt5A in the Melanoma Microenvironment and Depend on Wnt5A for Full Suppressive Activity. Cancer Res. 2021;81:658-670 pubmed publisher
Fane M, Ecker B, Kaur A, Marino G, Alicea G, Douglass S, et al. sFRP2 Supersedes VEGF as an Age-related Driver of Angiogenesis in Melanoma, Affecting Response to Anti-VEGF Therapy in Older Patients. Clin Cancer Res. 2020;26:5709-5719 pubmed publisher
Webster M, Fane M, Alicea G, Basu S, Kossenkov A, Marino G, et al. Paradoxical Role for Wild-Type p53 in Driving Therapy Resistance in Melanoma. Mol Cell. 2020;77:633-644.e5 pubmed publisher
Gao B, Ajima R, Yang W, Li C, Song H, Anderson M, et al. Coordinated directional outgrowth and pattern formation by integration of Wnt5a and Fgf signaling in planar cell polarity. Development. 2018;145: pubmed publisher
Ndoye A, Budina Kolomets A, Kugel C, Webster M, Kaur A, Behera R, et al. ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma. Cancer Res. 2017;77:5873-5885 pubmed publisher
Behera R, Kaur A, Webster M, Kim S, Ndoye A, Kugel C, et al. Inhibition of Age-Related Therapy Resistance in Melanoma by Rosiglitazone-Mediated Induction of Klotho. Clin Cancer Res. 2017;23:3181-3190 pubmed publisher
product information
master code :
BAF645
SKU :
BAF645
product name :
Mouse Wnt-5a Biotinylated Antibody
unit size :
50 ug
description :
The Mouse Wnt-5a Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to Wnt-5a. This antibody reacts with human,mouse. The Mouse Wnt-5a Biotinylated Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Western Blot.
target :
Wnt-5a
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Biotin
host :
Goat
immunogen :
E. coli -derived recombinant mouse Wnt-5a peptide, Gln254-Cys334, Accession # P22725
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects mouse Wnt-5a in Western blots. In this format, approximately 2% cross-reactivity with recombinant mouse Wnt-4 is observed.
gene symbol :
WNT5A
accessionNumbers :
P22725
applications :
Immunohistochemistry,Immunocytochemistry,Western Blot
USD :
529 USD
alt names :
hWNT5A, protein Wnt-5a, wingless-type MMTV integration site family, member 5A, Wnt5a, WNT-5A protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.