product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Mouse Mer Biotinylated Antibody
catalog :
BAF591
quantity :
50 ug
price :
609 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
biotin
reactivity :
mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, FACS
more info or order :
citations: 17
Reference
Bhattacharya P, Dhawan U, Hussain M, Singh P, Bhagat K, Singhal A, et al. Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling. Cell Rep. 2023;42:112808 pubmed publisher
Manickam V, Dhawan U, Singh D, Gupta M, Subramanian M. Pomegranate Peel Extract Decreases Plaque Necrosis and Advanced Atherosclerosis Progression in Apoe -/- Mice. Front Pharmacol. 2022;13:888300 pubmed publisher
Zhen Y, McGaha T, Finkelman F, Shao W. The Akt-mTORC1 pathway mediates Axl receptor tyrosine kinase-induced mesangial cell proliferation. J Leukoc Biol. 2022;111:563-571 pubmed publisher
Jesser E, Brady N, Huggins D, Witschen P, O Connor C, Schwertfeger K. STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment. Breast Cancer Res. 2021;23:104 pubmed publisher
Leach S, Gibbings S, Tewari A, Atif S, Vestal B, Danhorn T, et al. Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes. Cell Rep. 2020;33:108337 pubmed publisher
Bellomo A, Mondor I, Spinelli L, Lagueyrie M, Stewart B, Brouilly N, et al. Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages. Immunity. 2020;53:127-142.e7 pubmed publisher
Gay D, Ghinatti G, Guerrero Juarez C, Ferrer R, Ferri F, Lim C, et al. Phagocytosis of Wnt inhibitor SFRP4 by late wound macrophages drives chronic Wnt activity for fibrotic skin healing. Sci Adv. 2020;6:eaay3704 pubmed publisher
Salei N, Rambichler S, Salvermoser J, Papaioannou N, Schuchert R, Pakalniškytė D, et al. The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory Properties. J Am Soc Nephrol. 2020;31:257-278 pubmed publisher
Fujino N, Brand O, Morgan D, Fujimori T, Grabiec A, Jagger C, et al. Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases. J Exp Med. 2019;216:2184-2201 pubmed publisher
Mondor I, Baratin M, Lagueyrie M, Saro L, Henri S, Gentek R, et al. Lymphatic Endothelial Cells Are Essential Components of the Subcapsular Sinus Macrophage Niche. Immunity. 2019;50:1453-1466.e4 pubmed publisher
Nishi C, Yanagihashi Y, Segawa K, Nagata S. MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferation. J Biol Chem. 2019;294:7221-7230 pubmed publisher
Lee M, Chakhtoura M, Sriram U, Caricchio R, Gallucci S. Conventional DCs from Male and Female Lupus-Prone B6.NZM Sle1/Sle2/Sle3 Mice Express an IFN Signature and Have a Higher Immunometabolism That Are Enhanced by Estrogen. J Immunol Res. 2018;2018:1601079 pubmed publisher
Gounder A, Yokoyama C, Jarjour N, Bricker T, Edelson B, Boon A. Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer. PLoS Pathog. 2018;14:e1007001 pubmed publisher
Sheng J, Chen Q, Soncin I, Ng S, Karjalainen K, Ruedl C. A Discrete Subset of Monocyte-Derived Cells among Typical Conventional Type 2 Dendritic Cells Can Efficiently Cross-Present. Cell Rep. 2017;21:1203-1214 pubmed publisher
Doran A, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond C, et al. CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. J Clin Invest. 2017;127:4075-4089 pubmed publisher
Yanagihashi Y, Segawa K, Maeda R, Nabeshima Y, Nagata S. Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis. Proc Natl Acad Sci U S A. 2017;114:8800-8805 pubmed publisher
Barreiro O, Cibrian D, Clemente C, Alvarez D, Moreno V, Valiente I, et al. Pivotal role for skin transendothelial radio-resistant anti-inflammatory macrophages in tissue repair. elife. 2016;5: pubmed publisher
product information
master code :
BAF591
SKU :
BAF591
product name :
Mouse Mer Biotinylated Antibody
unit size :
50 ug
description :
The Mouse Mer Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to Mer. This antibody reacts with mouse,transgenic mouse. The Mouse Mer Biotinylated Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,ELISA Detection,FACS,Immunoprecipitation,Western Blot,Cell Culture,Immunocytochemistry.
target :
Mer
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Biotin
host :
Goat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Mer, Glu23-Phe498, Accession # Q60805
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Transgenic Mouse
specificity :
Detects mouse Mer in Western blots. In Western blots, no cross-reactivity with recombinant mouse (rm) Axl and rmDtk is observed.
gene symbol :
MERTK
top caption :
Detection of Mer antibody in J774A.1 Mouse Cell line antibody by Flow Cytometry.
accessionNumbers :
Q60805
applications :
Flow Cytometry,Immunohistochemistry,ELISA Detection,FACS,Immunoprecipitation,Western Blot,Cell Culture,Immunocytochemistry
USD :
609 USD
alt names :
c-Eyk, C-mer, c-mer proto-oncogene tyrosine kinase, EC 2.7.10, EC 2.7.10.1, MER, MER receptor tyrosine kinase, MerTK, MGC133349, Receptor tyrosine kinase MerTK, RP38Proto-oncogene c-Mer, STK kinase, tyrosine-protein kinase Mer
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.