product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse IL-12/IL-23 p40 Biotinylated Antibody
catalog :
BAF499
quantity :
50 ug
price :
569 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
biotin
reactivity :
human, mouse
application :
western blot, ELISA
more info or order :
citations: 3
Reference
Lee S, Moon S, Moon Y, Seo H, Ryu J, Lee A, et al. A novel cytokine consisting of the p40 and EBI3 subunits suppresses experimental autoimmune arthritis via reciprocal regulation of Th17 and Treg cells. Cell Mol Immunol. 2022;19:79-91 pubmed publisher
Georgy J, Arlt Y, Moll J, Ouzin M, Weitz H, Gremer L, et al. Tryptophan (W) at position 37 of murine IL-12/IL-23 p40 is mandatory for binding to IL-12Rβ1 and subsequent signal transduction. J Biol Chem. 2021;297:101295 pubmed publisher
Geissler R, Simkin A, Floss D, Patel R, Fogarty E, Scheller J, et al. A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1. Genes Dev. 2016;30:1070-85 pubmed publisher
product information
brand :
R&D Systems
master code :
BAF499
SKU :
BAF499
product name :
Mouse IL-12/IL-23 p40 Biotinylated Antibody
unit size :
50 ug
seo description :
The Mouse IL-12/IL-23 p40 Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to IL-12/IL-23 p40. This antibody reacts with human,mouse. The Mouse IL-12/IL-23 p40 Biotinylated Antibody has been validated for the following applications: ELISA Development,Western Blot,Direct ELISA,ELISA Detection (Matched Antibody Pair).
target :
IL-12/IL-23 p40
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Biotin
dilution :
Western Blot 0.1 ug/mL, ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL, ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL, ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
host :
Goat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse IL-12 p40, Met23-Ser355, Accession # P43432
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects mouse IL-12 p40 in ELISAs and Western blots. In sandwich immunoassays, approximately 30% cross-reactivity with recombinant mouse IL-12 p70 is observed.
gene symbol :
Il12b
accessionNumbers :
P43432
applications :
ELISA Detection (Matched Antibody Pair),ELISA Development,Western Blot,Direct ELISA
USD :
569 USD
alt names :
CLMF, CLMF p40, CLMF2, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL12 p40, IL-12 subunit p40, IL12B, IL-12B, IL-12BNK cell stimulatory factor chain 2, interleukin 12, p40, interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocytematuration factor 2, p40), interleukin-12 beta chain, interleukin-12 subunit beta, natural killer cell stimulatory factor, 40 kD subunit, NKSF, NKSF2, NKSF2IL12, subunit p40
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.