Mouse IL-1▀/IL-1F2 Biotinylated Antibody | R&D Systems BAF401 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-1▀/IL-1F2 Biotinylated Antibody

catalog :

BAF401

quantity :

50 ug

price :

559 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

biotin

reactivity :

human, mouse

application :

western blot, ELISA

more info or order :

R&D Systems product webpage

citations: 22

Reference
Xian H, Watari K, Sanchez Lopez E, Offenberger J, Onyuru J, Sampath H, et al. Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling. Immunity. 2022;55:1370-1385.e8 pubmed publisher
Bertheloot D, Wanderley C, Schneider A, Schiffelers L, Wuerth J, T xf6 dtmann J, et al. Nanobodies dismantle post-pyroptotic ASC specks and counteract inflammation in vivo. EMBO Mol Med. 2022;14:e15415 pubmed publisher
West A, Deswaerte V, West A, Gearing L, Tan P, Jenkins B. Inflammasome-Associated Gastric Tumorigenesis Is Independent of the NLRP3 Pattern Recognition Receptor. Front Oncol. 2022;12:830350 pubmed publisher
Xian H, Liu Y, Rundberg Nilsson A, Gatchalian R, Crother T, Tourtellotte W, et al. Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation. Immunity. 2021;54:1463-1477.e11 pubmed publisher
Kim G, Choi K, Kim H, Chung D. Alleviation of LPS-Induced Inflammation and Septic Shock by Lactiplantibacillus plantarum K8 Lysates. Int J Mol Sci. 2021;22: pubmed publisher
Childers G, Perry C, Blachut B, Martin N, Bortner C, Sieber S, et al. Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin Compounds. Environ Health Perspect. 2021;129:47015 pubmed publisher
Tsuchiya K, Hosojima S, Hara H, Kushiyama H, Mahib M, Kinoshita T, et al. Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes. Cell Rep. 2021;34:108887 pubmed publisher
Van Belle S, de Lange A, Tomes H, Lucas R, Naidoo V, Raimondo J. Peripheral Taenia infection increases immunoglobulins in the central nervous system. Int J Parasitol. 2021;51:685-692 pubmed publisher
Min H, Won J, Kim B, Lee K, Lee S, Lee S, et al. Interleukin (IL)-25 suppresses IL-22-induced osteoclastogenesis in rheumatoid arthritis via STAT3 and p38 MAPK/IκBα pathway. Arthritis Res Ther. 2020;22:222 pubmed publisher
Shippy D, Wilhelm C, Viharkumar P, Raife T, Ulland T. β-Hydroxybutyrate inhibits inflammasome activation to attenuate Alzheimer's disease pathology. J Neuroinflammation. 2020;17:280 pubmed publisher
Donado C, Cao A, Simmons D, Croker B, Brennan P, Brenner M. A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling. Cell Rep. 2020;31:107466 pubmed publisher
Kim D, Choi J, Jo I, Kim M, Lee H, Hong S, et al. Berberine ameliorates lipopolysaccharide‑induced inflammatory responses in mouse inner medullary collecting duct‑3 cells by downregulation of NF‑κB pathway. Mol Med Rep. 2020;21:258-266 pubmed publisher
Pang Z, Raudonis R, McCormick C, Cheng Z. Early Growth Response 1 Deficiency Protects the Host against Pseudomonas aeruginosa Lung Infection. Infect Immun. 2019;88: pubmed publisher
Polykratis A, Martens A, Eren R, Shirasaki Y, Yamagishi M, Yamaguchi Y, et al. A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain. Nat Cell Biol. 2019;21:731-742 pubmed publisher
Sanchez Lopez E, Zhong Z, Stubelius A, Sweeney S, Booshehri L, Antonucci L, et al. Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production. Cell Metab. 2019;29:1350-1362.e7 pubmed publisher
Orimo T, Sasaki I, Hemmi H, Ozasa T, Fukuda Ohta Y, Ohta T, et al. Cholera toxin B induces interleukin-1β production from resident peritoneal macrophages through the pyrin inflammasome as well as the NLRP3 inflammasome. Int Immunol. 2019;31:657-668 pubmed publisher
Kolb R, Kluz P, Tan Z, Borcherding N, Bormann N, Vishwakarma A, et al. Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4. Oncogene. 2019;38:2351-2363 pubmed publisher
Zhong Z, Liang S, Sanchez Lopez E, He F, Shalapour S, Lin X, et al. New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. Nature. 2018;560:198-203 pubmed publisher
Pang Z, Junkins R, MacNeil A, McCormick C, Cheng Z, Chen W, et al. The calcineurin-NFAT axis contributes to host defense during Pseudomonas aeruginosa lung infection. J Leukoc Biol. 2017;: pubmed publisher
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Ha S, Sung J, Choi I, Kim Y. Oryza sativa (Rice) Hull Extract Inhibits Lipopolysaccharide-Induced Inflammatory Response in RAW264.7 Macrophages by Suppressing Extracellular Signal-regulated Kinase, c-Jun N-terminal Kinase, and Nuclear Factor-κB Activation. Pharmacogn Mag. 2016;12:295-301 pubmed

product information

brand :

R&D Systems

master code :

BAF401

SKU :

BAF401

product name :

Mouse IL-1▀/IL-1F2 Biotinylated Antibody

unit size :

50 ug

seo description :

The Mouse IL-1ß/IL-1F2 Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to IL-1 beta/IL-1F2. This antibody reacts with human,mouse,transgenic mouse. The Mouse IL-1ß/IL-1F2 Biotinylated Antibody has been validated for the following applications: Western Blot,ELISA Detection,Bioassay,ELISA Development,ELISA Development (Detection),Luminex Development,ELISA Capture,ELISA Detection (Matched Antibody Pair).

target :

IL-1 beta/IL-1F2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Biotin

dilution :

Western Blot 0.1 ug/mL, ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant mouse IL-1▀ (R D Systems, Catalog # 401-ML), Val118-Ser269, Accession # NP_032387

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Transgenic Mouse

specificity :

Detects mouse IL-1▀ in ELISAs and Western blots. In sandwich immunoassays, less than 4% cross-reactivity with recombinant rat (rr) IL-1▀ is observed and less than 0.05% cross-reactivity with rhIL-1▀ and rmIL-1 alpha is observed.

gene symbol :

IL1B

top caption :

Detection of Mouse IL-1 beta/IL-1F2 by Western Blot

accessionNumbers :

NP_032387

applications :

ELISA Detection (Matched Antibody Pair),Bioassay,ELISA Development,ELISA Development (Detection),Luminex Development,Western Blot,ELISA Capture,ELISA Detection

USD :

559 USD

alt names :

catabolin, IL-1, IL1 beta, IL-1 beta, IL-1b, IL1B, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin 1, beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage