Human/Primate BMP-9 Biotinylated Antibody | R&D Systems BAF3209 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Primate BMP-9 Biotinylated Antibody

catalog :

BAF3209

quantity :

50 ug

price :

579 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

biotin

reactivity :

human, mouse

application :

ELISA

more info or order :

R&D Systems product webpage

citations: 7

Reference
Hodgson J, Ruiz Llorente L, McDonald J, Quarrell O, Ugonna K, Bentham J, et al. Homozygous GDF2 nonsense mutations result in a loss of circulating BMP9 and BMP10 and are associated with either PAH or an "HHT-like" syndrome in children. Mol Genet Genomic Med. 2021;9:e1685 pubmed publisher
Owen N, Alexander G, Sen S, Bunclark K, Polwarth G, Pepke Zaba J, et al. Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis. EBioMedicine. 2020;56:102794 pubmed publisher
Desroches Castan A, Tillet E, Ricard N, Ouarné M, Mallet C, Feige J, et al. Differential Consequences of Bmp9 Deletion on Sinusoidal Endothelial Cell Differentiation and Liver Fibrosis in 129/Ola and C57BL/6 Mice. Cells. 2019;8: pubmed publisher
Tillet E, Ouarné M, Desroches Castan A, Mallet C, Subileau M, Didier R, et al. A heterodimer formed by bone morphogenetic protein 9 (BMP9) and BMP10 provides most BMP biological activity in plasma. J Biol Chem. 2018;293:10963-10974 pubmed publisher
Graf S, Haimel M, Bleda M, Hadinnapola C, Southgate L, Li W, et al. Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. Nat Commun. 2018;9:1416 pubmed publisher
Breitkopf Heinlein K, Meyer C, KÃ¶nig C, Gaitantzi H, Addante A, Thomas M, et al. BMP-9 interferes with liver regeneration and promotes liver fibrosis. Gut. 2017;66:939-954 pubmed publisher
Kienast Y, Jucknischke U, Scheiblich S, Thier M, de Wouters M, Haas A, et al. Rapid Activation of Bone Morphogenic Protein 9 by Receptor-mediated Displacement of Pro-domains. J Biol Chem. 2016;291:3395-410 pubmed publisher

product information

brand :

R&D Systems

master code :

BAF3209

SKU :

BAF3209

product name :

Human/Primate BMP-9 Biotinylated Antibody

unit size :

50 ug

seo description :

The Human/Primate BMP-9 Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to BMP-9. This antibody reacts with human,mouse,primate. The Human/Primate BMP-9 Biotinylated Antibody has been validated for the following applications: ELISA (detection),ELISA Development (Detection),ELISA Detection,ELISA Detection (Matched Antibody Pair).

target :

BMP-9

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Biotin

dilution :

ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant human BMP-9, Ser320-Arg429, Accession # Q9UK05

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Primate

specificity :

Detects human and primate BMP-9 in Western blots and ELISAs. In sandwich immunoassays, less than 0.1% cross-reactivity with recombinant human (rh) BMP-3, rhBMP-4, rhBMP-5, rhBMP-6, rhBMP-7, and rhBMP-10 is observed.

gene symbol :

GDF2

accessionNumbers :

Q9UK05

applications :

ELISA Detection (Matched Antibody Pair),ELISA (detection),ELISA Development (Detection),ELISA Detection

USD :

579 USD

alt names :

BMP9, BMP9BMP-9Bone morphogenetic protein 9, GDF2, GDF-2, growth differentiation factor 2, growth/differentiation factor 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage