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company name :
R&D Systems
product type :
antibody
product name :
Human/Primate IL-17/IL-17A Biotinylated Antibody
catalog :
BAF317
quantity :
50 ug
price :
569 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
biotin
reactivity :
human
application :
ELISA, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 10
Reference
Gorchs L, Ahmed S, Mayer C, Knauf A, Fernández Moro C, Svensson M, et al. The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity. Sci Rep. 2020;10:17444 pubmed publisher
Toledo N, Li H, Omange R, Dacoba T, Crecente Campo J, Schalk D, et al. Cervico-Vaginal Inflammatory Cytokine and Chemokine Responses to Two Different SIV Immunogens. Front Immunol. 2020;11:1935 pubmed publisher
Bouhaddou M, Memon D, Meyer B, White K, Rezelj V, Correa Marrero M, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020;182:685-712.e19 pubmed publisher
Yan J, Pandey S, Barnes B, Turner J, Abraham C. T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation. Cell Rep. 2020;31:107820 pubmed publisher
Haug V, Kollar B, Tasigiorgos S, Endo Y, Kauke M, Safi A, et al. Hypothermic Ex Situ Perfusion of Human Limbs With Acellular Solution for 24 Hours. Transplantation. 2020;104:e260-e270 pubmed publisher
Teng Y, Young J, Edwards B, HAYES P, Thompson L, Johnston C, et al. Diverse human VH antibody fragments with bio-therapeutic properties from the Crescendo Mouse. N Biotechnol. 2020;55:65-76 pubmed publisher
Chamcheu J, Esnault S, Adhami V, Noll A, Banang Mbeumi S, Roy T, et al. Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models. Cells. 2019;8: pubmed publisher
Lv R, Zhao J, Lei M, Xiao D, Yu Y, Xie J. IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3. Cell Physiol Biochem. 2017;42:1961-1972 pubmed publisher
Brencicova E, Jagger A, Evans H, Georgouli M, Laios A, Attard Montalto S, et al. Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma. PLoS ONE. 2017;12:e0175712 pubmed publisher
Hull D, Cooksley H, Chokshi S, Williams R, Abraham S, Taylor P. Increase in circulating Th17 cells during anti-TNF therapy is associated with ultrasonographic improvement of synovitis in rheumatoid arthritis. Arthritis Res Ther. 2016;18:303 pubmed publisher
product information
brand :
R&D Systems
master code :
BAF317
SKU :
BAF317
product name :
Human/Primate IL-17/IL-17A Biotinylated Antibody
unit size :
50 ug
seo description :
The Human/Primate IL-17/IL-17A Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to IL-17/IL-17A. This antibody reacts with human,primate. The Human/Primate IL-17/IL-17A Biotinylated Antibody has been validated for the following applications: ELISA Development,ELISA Development (Detection),Luminex Development,Functional Assay,ELISA Capture,ELISA Detection,Immunohistochemistry-Paraffin,Immunohistochemistry,ELISA Detection (Matched Antibody Pair).
target :
IL-17/IL-17A
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Biotin
dilution :
Immunohistochemistry 0.3-15 ug/mL, ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant human IL-17, Ile20-Ala155, Accession # Q16552
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Primate
specificity :
Detects human and primate IL-17 in direct ELISAs. In sandwich immunoassays, approximately 22% cross-reactivity with rhIL-17A/F heterodimer is observed, and less than 0.05% cross-reactivity with recombinant mouse (rm) IL-17, recombinant human (rh) IL-10, rhIL-12, rhIL-16, rhIFN-gamma , rhIL-17B, rhIL-17C, rhIL-17D, rhIL-17E and rhIL-17F is observed.
gene symbol :
IL17A
top caption :
IL-17/IL-17A antibody in Human Crohn's Disease Intestine by Immunohistochemistry (IHC-P).
accessionNumbers :
Q16552
applications :
Immunohistochemistry,ELISA Detection (Matched Antibody Pair),ELISA Development,ELISA Development (Detection),Luminex Development,Immunohistochemistry-Paraffin,Functional Assay,ELISA Capture,ELISA Detection
USD :
569 USD
alt names :
CTLA8, CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.