Human IL-7R alpha /CD127 Biotinylated Antibody | R&D Systems BAF306 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-7R alpha /CD127 Biotinylated Antibody

catalog :

BAF306

quantity :

50 ug

price :

569 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

biotin

reactivity :

human

application :

western blot, ELISA, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Galarza Mu xf1 oz G, Kennedy Boone D, Schott G, Bradrick S, Garcia Blanco M. Antisense modulation of IL7R splicing to control sIL7R expression in human CD4+ T cells. RNA. 2022;28:1058-1073 pubmed publisher
Hehenkamp P, Hoffmann M, Kummer S, Reinauer C, D xf6 ing C, F xf6 rtsch K, et al. Interleukin-7-dependent nonclassical monocytes and CD40 expression are affected in children with type 1 diabetes. Eur J Immunol. 2021;51:3214-3227 pubmed publisher
Côté S, Burke Schinkel S, Berthoud T, Barros P, Sanchez Vidales M, Davidson A, et al. IL-7 induces sCD127 release and mCD127 downregulation in human CD8+ T cells by distinct yet overlapping mechanisms, both of which are impaired in HIV infection. Eur J Immunol. 2020;50:1537-1549 pubmed publisher
Al Mossawi H, Yager N, Taylor C, Lau E, Danielli S, de Wit J, et al. Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele. Nat Commun. 2019;10:4575 pubmed publisher
Judge C, Kostadinova L, Sherman K, Butt A, Falck Ytter Y, Funderburg N, et al. CD56bright NK IL-7Rα expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections. J Leukoc Biol. 2017;102:171-184 pubmed publisher
GALARZA MUNOZ G, Briggs F, Evsyukova I, Schott Lerner G, Kennedy E, Nyanhete T, et al. Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk. Cell. 2017;169:72-84.e13 pubmed publisher

product information

master code :

BAF306

SKU :

BAF306

product name :

Human IL-7R alpha /CD127 Biotinylated Antibody

unit size :

50 ug

description :

The Human IL-7R alpha /CD127 Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to IL-7R alpha/CD127. This antibody reacts with human. The Human IL-7R alpha /CD127 Biotinylated Antibody has been validated for the following applications: ELISA Detection,ELISA Development,ELISA Development (Detection),Flow Cytometry,Western Blot.

target :

IL-7R alpha/CD127

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Biotin

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IL-7 R alpha , Extracellular domain

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human IL-7 R alpha in Western blots.

gene symbol :

IL7R

applications :

ELISA Detection,ELISA Development,ELISA Development (Detection),Flow Cytometry,Western Blot

USD :

569 USD

alt names :

CD127, CD127 antigen, CD127ILRA, CDW127, IL-7 R alpha, IL-7 receptor subunit alpha, IL7R, IL7R alpha, IL-7R subunit alpha, IL7RA, IL-7RA, IL-7R-alpha, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, interleukin-7 receptor subunit alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage