product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Progranulin/PGRN Biotinylated Antibody
catalog :
BAF2420
quantity :
50 ug
price :
549 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
biotin
reactivity :
human
application :
western blot, ELISA
more info or order :
citations: 3
Reference
Schulze Edinghausen L, Dürr C, Oztürk S, Zucknick M, Benner A, Kalter V, et al. Dissecting the Prognostic Significance and Functional Role of Progranulin in Chronic Lymphocytic Leukemia. Cancers (Basel). 2019;11: pubmed publisher
Götzl J, Brendel M, Werner G, Parhizkar S, Sebastian Monasor L, Kleinberger G, et al. Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism. EMBO Mol Med. 2019;: pubmed publisher
Suarez Calvet M, Capell A, Araque Caballero M, Morenas Rodríguez E, Fellerer K, Franzmeier N, et al. CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. EMBO Mol Med. 2018;10: pubmed publisher
product information
brand :
R&D Systems
master code :
BAF2420
SKU :
BAF2420
product name :
Human Progranulin/PGRN Biotinylated Antibody
unit size :
50 ug
seo description :
The Human Progranulin/PGRN Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to Progranulin/PGRN. This antibody reacts with human. The Human Progranulin/PGRN Biotinylated Antibody has been validated for the following applications: ELISA Development,ELISA Development (Capture),ELISA Capture,ELISA Detection,Western Blot.
target :
Progranulin/PGRN
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Biotin
dilution :
Western Blot 0.1 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Progranulin (R D Systems, Catalog # 2420-PG), Thr18-Leu593, Accession # P28799
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human Progranulin in Western blots. In this format, approximately 35% cross-reactivity with recombinant mouse Progranulin is observed.
gene symbol :
GRN
accessionNumbers :
P28799
applications :
Western Blot,ELISA Development,ELISA Development (Capture),ELISA Capture,ELISA Detection
USD :
549 USD
alt names :
Acrogranin, CLN11, GEP, GP88, granulin precursor, GRN, PCDGF, PEPI, PGRN, Proepithelin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.