product summary
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company name :
R&D Systems
product type :
antibody
product name :
TGF┐▀1 Biotinylated Antibody
catalog :
BAF240
quantity :
50 ug
price :
559 USD
clonality :
polyclonal
host :
chicken
conjugate :
biotin
reactivity :
human, mouse, rat
application :
western blot, ELISA, neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 8
Reference
Gringhuis S, Kaptein T, Remmerswaal E, Drewniak A, Wevers B, Theelen B, et al. Fungal sensing by dectin-1 directs the non-pathogenic polarization of TH17 cells through balanced type I IFN responses in human DCs. Nat Immunol. 2022;23:1735-1748 pubmed publisher
Kadam A, Kandasamy K, Buss T, Cederstrom B, Yang C, Narayanapillai S, et al. Targeting caveolae to pump bispecific antibody to TGF-β into diseased lungs enables ultra-low dose therapeutic efficacy. PLoS ONE. 2022;17:e0276462 pubmed publisher
Amer S, Abdel Wareth A, Gouda A, Saleh G, Nassar A, Sherief W, et al. Impact of Dietary Lavender Essential Oil on the Growth and Fatty Acid Profile of Breast Muscles, Antioxidant Activity, and Inflammatory Responses in Broiler Chickens. Antioxidants (Basel). 2022;11: pubmed publisher
Poosti F, Soebadi M, Crijns H, De Zutter A, Metzemaekers M, Berghmans N, et al. Inhibition of renal fibrosis with a human CXCL9-derived glycosaminoglycan-binding peptide. Clin Transl Immunology. 2022;11:e1370 pubmed publisher
Li S, Liu M, Do M, Chou C, Stamatiades E, Nixon B, et al. Cancer immunotherapy via targeted TGF-β signalling blockade in TH cells. Nature. 2020;587:121-125 pubmed publisher
Kaushansky N, Bakos E, Becker Herman S, Shachar I, Ben Nun A. Circulating Picomolar Levels of CCL2 Downregulate Ongoing Chronic Experimental Autoimmune Encephalomyelitis by Induction of Regulatory Mechanisms. J Immunol. 2019;203:1857-1866 pubmed publisher
Yu H, Ma S, Sun L, Gao J, Zhao C. TGF‑β1 upregulates the expression of lncRNA‑ATB to promote atherosclerosis. Mol Med Rep. 2019;19:4222-4228 pubmed publisher
Ravi R, Noonan K, Pham V, Bedi R, Zhavoronkov A, Ozerov I, et al. Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy. Nat Commun. 2018;9:741 pubmed publisher
product information
brand :
R&D Systems
master code :
BAF240
SKU :
BAF240
product name :
TGF┐▀1 Biotinylated Antibody
unit size :
50 ug
seo description :
The TGF¿ß1 Biotinylated Antibody from R&D Systems is a chicken polyclonal antibody to TGF-beta 1. This antibody reacts with human,mouse,multi-species,porcine,primate - papio anubis (olive baboon),rat. The TGF¿ß1 Biotinylated Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,ELISA Detection,ELISA Development,ELISA Development (Detection),Luminex Development,Western Blot,Neutralization,ELISA Detection (Matched Antibody Pair).
target :
TGF-beta 1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Biotin
dilution :
Western Blot 0.1 ug/mL, ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
host :
Chicken
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human TGF┐▀1 (R D Systems, Catalog # 240-B)
isotype :
IgY
purity :
Antigen Affinity-purified from egg yolks
species :
Human,Mouse,Multi-Species,Porcine,Primate - Papio anubis (Olive Baboon),Rat
specificity :
Detects human TGF┐▀1 in ELISAs and Western blots. In sandwich immunoassays, when used in combination with the rhTGF┐▀ sRII/Fc chimera (Catalog # 341-BR), approximately 15% cross-reactivity with recombinant human (rh) Latent TGF┐▀1 is observed, 1% cross-reactivity with rhTGF┐▀1.2 is observed, and 3% cross-reactivity with recombinant amphibian (ra) TGF┐▀5 is observed. When used in combination with the monoclonal capture antibody (Catalog # MAB2402), approximately 5% cross-reactivity with TGF┐▀1.2 is observed and 1% cross-reactivity with rhTGF┐▀2, recombinant chicken TGF┐▀3, and raTGF┐▀5 is observed.
gene symbol :
TGFB1
applications :
ELISA Detection (Matched Antibody Pair),ELISA Development,ELISA Development (Detection),Luminex Development,Flow Cytometry,Western Blot,Neutralization,ELISA Detection
USD :
559 USD
alt names :
CEDLAP, DPD1, latency-associated peptide, TGF beta, TGF beta1, TGFB, TGFB1, TGFbeta, TGFbeta 1, TGF-beta 1 protein, TGF-beta-1, transforming growth factor beta-1, transforming growth factor, beta 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.