product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human GDNF Biotinylated Antibody
catalog :
BAF212
quantity :
50 ug
price :
549 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
biotin
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 5
Reference
Azevedo M, Prince N, Humbert Claude M, Mesa Infante V, Jeanneret C, Golzné V, et al. Oxidative stress induced by sustained supraphysiological intrastriatal GDNF delivery is prevented by dose regulation. Mol Ther Methods Clin Dev. 2023;31:101106 pubmed publisher
Stahn L, Rasi x144 ska J, Dehne T, Schreyer S, Hakus A, Gossen M, et al. Sleeping Beauty transposon system for GDNF overexpression of entrapped stem cells in fibrin hydrogel in a rat model of Parkinson's disease. Drug Deliv Transl Res. 2023;13:1745-1765 pubmed publisher
Baloh R, Johnson J, Avalos P, Allred P, Svendsen S, Gowing G, et al. Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial. Nat Med. 2022;28:1813-1822 pubmed publisher
Dulz S, Bassal M, Flachsbarth K, Riecken K, Fehse B, Schlichting S, et al. Intravitreal Co-Administration of GDNF and CNTF Confers Synergistic and Long-Lasting Protection against Injury-Induced Cell Death of Retinal Ganglion Cells in Mice. Cells. 2020;9: pubmed publisher
Luz M, Allen P, Bringas J, Boiko C, Stockinger D, Nikula K, et al. Intermittent convection-enhanced delivery of GDNF into rhesus monkey putamen: absence of local or cerebellar toxicity. Arch Toxicol. 2018;92:2353-2367 pubmed publisher
product information
master code :
BAF212
SKU :
BAF212
product name :
Human GDNF Biotinylated Antibody
unit size :
50 ug
description :
The Human GDNF Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to GDNF. This antibody reacts with human,mouse,primate - chlorocebus sabaeus (green monkey),rat. The Human GDNF Biotinylated Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot,ELISA Detection (Matched Antibody Pair).
target :
GDNF
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Biotin
host :
Goat
immunogen :
E. coli -derived and Mouse myeloma cell line NS0-derived recombinant human GDNF, Arg109-Ile211, Accession # P39905
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Primate - Chlorocebus sabaeus (Green Monkey),Rat
specificity :
Detects human GDNF in ELISAs and Western blots. In sandwich immunoassays, less than 30% cross-reactivity with recombinant rat GDNF is observed and less than 0.1% cross-reativity with recombinant human (rh) BDNF, rhCNTF, rhNeurturin, rh▀-NGF, rhNT-3, and rhNT-4 is observed.
gene symbol :
GDNF
accessionNumbers :
P39905
applications :
Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot,ELISA Detection (Matched Antibody Pair)
USD :
549 USD
alt names :
Astrocyte-derived trophic factor, ATF, ATF1, ATF2, glial cell derived neurotrophic factor, glial cell line derived neurotrophic factor, glial cell line-derived neurotrophic factor, HFB1-GDNF, HGDNF, HSCR3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.