Human Otx2 Biotinylated Antibody | R&D Systems BAF1979 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Otx2 Biotinylated Antibody

catalog :

BAF1979

quantity :

50 ug

price :

529 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

biotin

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 19

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:400; loading ...; fig 7h	Völkner M, Kurth T, Schor J, Ebner L, Bardtke L, Kavak C, et al. Mouse Retinal Organoid Growth and Maintenance in Longer-Term Culture. Front Cell Dev Biol. 2021;9:645704 pubmed publisher
	Tresenrider A, Hooper M, Todd L, Kierney F, Blasdel N, Trapnell C, et al. A multiplexed, single-cell sequencing screen identifies compounds that increase neurogenic reprogramming of murine Muller glia. bioRxiv. 2024;: pubmed publisher
	Palazzo I, Todd L, Hoang T, Reh T, Blackshaw S, Fischer A. NFkB-signaling promotes glial reactivity and suppresses Müller glia-mediated neuron regeneration in the mammalian retina. Glia. 2022;70:1380-1401 pubmed publisher
	Finkbeiner C, Ortu xf1 o Lizar xe1 n I, Sridhar A, Hooper M, Petter S, Reh T. Single-cell ATAC-seq of fetal human retina and stem-cell-derived retinal organoids shows changing chromatin landscapes during cell fate acquisition. Cell Rep. 2022;38:110294 pubmed publisher
	Todd L, Hooper M, Haugan A, Finkbeiner C, Jorstad N, Radulovich N, et al. Efficient stimulation of retinal regeneration from Müller glia in adult mice using combinations of proneural bHLH transcription factors. Cell Rep. 2021;37:109857 pubmed publisher
	Fishman E, Louie M, Miltner A, Cheema S, Wong J, Schlaeger N, et al. MicroRNA Signatures of the Developing Primate Fovea. Front Cell Dev Biol. 2021;9:654385 pubmed publisher
	Todd L, Finkbeiner C, Wong C, Hooper M, Reh T. Microglia Suppress Ascl1-Induced Retinal Regeneration in Mice. Cell Rep. 2020;33:108507 pubmed publisher
	Goodson N, Kaufman M, Park K, Brzezinski J. Simultaneous deletion of Prdm1 and Vsx2 enhancers in the retina alters photoreceptor and bipolar cell fate specification, yet differs from deleting both genes. Development. 2020;147: pubmed publisher
	Jorstad N, Wilken M, Todd L, Finkbeiner C, NAKAMURA P, Radulovich N, et al. STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina. Cell Rep. 2020;30:2195-2208.e5 pubmed publisher
	Sridhar A, Hoshino A, Finkbeiner C, Chitsazan A, Dai L, Haugan A, et al. Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures. Cell Rep. 2020;30:1644-1659.e4 pubmed publisher
	Bosze B, Moon M, Kageyama R, Brown N. Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. J Neurosci. 2020;40:1501-1513 pubmed publisher
	Hoshino A, Horvath S, Sridhar A, Chitsazan A, Reh T. Synchrony and asynchrony between an epigenetic clock and developmental timing. Sci Rep. 2019;9:3770 pubmed publisher
	Fairchild C, Hino K, Han J, Miltner A, Peinado Allina G, Brown C, et al. RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018;145: pubmed publisher
	Mills T, Eliseeva T, Bersie S, Randazzo G, Nahreini J, Park K, et al. Combinatorial regulation of a Blimp1 (Prdm1) enhancer in the mouse retina. PLoS ONE. 2017;12:e0176905 pubmed publisher
	Jorstad N, Wilken M, Grimes W, Wohl S, VandenBosch L, Yoshimatsu T, et al. Stimulation of functional neuronal regeneration from Müller glia in adult mice. Nature. 2017;548:103-107 pubmed publisher
	Sharma T, Wiley L, Whitmore S, Anfinson K, Cranston C, Oppedal D, et al. Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa. Stem Cell Res. 2017;21:58-70 pubmed publisher
	Moshiri A, Humpal D, Leonard B, Imai D, Tham A, Bower L, et al. Arap1 Deficiency Causes Photoreceptor Degeneration in Mice. Invest Ophthalmol Vis Sci. 2017;58:1709-1718 pubmed publisher
	Park K, Randazzo G, Jones K, Brzezinski J. Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar Interneurons in the Mouse Retina. Invest Ophthalmol Vis Sci. 2017;58:1137-1150 pubmed publisher
	Wiley L, Burnight E, DeLuca A, Anfinson K, Cranston C, Kaalberg E, et al. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Sci Rep. 2016;6:30742 pubmed publisher

product information

brand :

R&D Systems

master code :

BAF1979

SKU :

BAF1979

product name :

Human Otx2 Biotinylated Antibody

unit size :

50 ug

seo description :

The Human Otx2 Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to Otx2. This antibody reacts with human,mouse,transgenic mouse. The Human Otx2 Biotinylated Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunofluorescence,Immunocytochemistry.

target :

Otx2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Biotin

dilution :

Western Blot 0.1 ug/mL, Immunocytochemistry 5-15 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant human Otx2, Met1-Leu289, Accession # P32243

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Transgenic Mouse

specificity :

Detects human Otx2 in Western blots.

gene symbol :

OTX2

top caption :

Otx2 antibody in BG01V Human Embryonic Stem Cells by Immunocytochemistry (ICC).

accessionNumbers :

P32243

applications :

Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunofluorescence,Immunocytochemistry

USD :

529 USD

alt names :

homeobox protein OTX2, MCOPS5, MGC45000, orthodenticle homeobox 2, Orthodenticle homolog 2, orthodenticle homolog 2 (Drosophila), OTX2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage