product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-23R Biotinylated Antibody
catalog :
BAF1400
quantity :
50 ug
price :
529 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
biotin
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 5
Reference
Georgy J, Arlt Y, Moll J, Ouzin M, Weitz H, Gremer L, et al. Tryptophan (W) at position 37 of murine IL-12/IL-23 p40 is mandatory for binding to IL-12Rβ1 and subsequent signal transduction. J Biol Chem. 2021;297:101295 pubmed publisher
Kim D, Kim H, Cho S, Yoo S, Kim W, Yeon H, et al. Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells. elife. 2021;10: pubmed publisher
Esch A, Masiarz A, Mossner S, Moll J, Grötzinger J, Schröder J, et al. Deciphering site 3 interactions of interleukin 12 and interleukin 23 with their cognate murine and human receptors. J Biol Chem. 2020;295:10478-10492 pubmed publisher
Liu D, Xing S, Wang W, Huang X, Lin H, Chen Y, et al. Prognostic value of serum soluble interleukin-23 receptor and related T-helper 17 cell cytokines in non-small cell lung carcinoma. Cancer Sci. 2020;111:1093-1102 pubmed publisher
Hummel T, Ackfeld T, Schönberg M, Ciupka G, Schulz F, Oberdoerster A, et al. Synthetic Deletion of the Interleukin 23 Receptor (IL-23R) Stalk Region Led to Autonomous IL-23R Homodimerization and Activation. Mol Cell Biol. 2017;37: pubmed publisher
product information
brand :
R&D Systems
master code :
BAF1400
SKU :
BAF1400
product name :
Human IL-23R Biotinylated Antibody
unit size :
50 ug
seo description :
The Human IL-23R Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to IL-23R. This antibody reacts with human,mouse. The Human IL-23R Biotinylated Antibody has been validated for the following applications: ELISA (detection),ELISA Development,ELISA Development (Detection),Flow Cytometry,Western Blot,Immunocytochemistry.
target :
IL-23R
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Biotin
dilution :
Western Blot 0.1 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human IL-23 R, Gly24-Ile353, Accession # Q5VWK5
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human IL-23 R in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse IL-23 R is observed.
gene symbol :
IL23R
accessionNumbers :
Q5VWK5
applications :
ELISA (detection),ELISA Development,ELISA Development (Detection),Flow Cytometry,Western Blot,Immunocytochemistry
USD :
529 USD
alt names :
IBD17, IL-23 R, IL-23 receptor, IL23R, IL-23R, interleukin 23 receptor, interleukin-23 receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.