product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Galectin-3 Biotinylated Antibody
catalog :
BAF1154
quantity :
50 ug
price :
549 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
biotin
reactivity :
human
application :
western blot, ELISA, immunoprecipitation, flow cytometry
more info or order :
citations: 8
Reference
Wan Y, Adair K, Herrmann A, Shan X, Xia L, Duckworth C, et al. C1GalT1 expression reciprocally controls tumour cell-cell and tumour-macrophage interactions mediated by galectin-3 and MGL with double impact on cancer development and progression. Cell Death Dis. 2023;14:547 pubmed publisher
Hsu H, Yang Y, Huang Y, Chu C, Tu T, Wu Y, et al. Distinct features of the host-parasite interactions between nonadherent and adherent Trichomonas vaginalis isolates. PLoS Negl Trop Dis. 2023;17:e0011016 pubmed publisher
Pang Y, Maxwell E, Sindrewicz Goral P, Shapanis A, Li S, Morgan M, et al. Galectin-3 Is a Natural Binding Ligand of MCAM (CD146, MUC18) in Melanoma Cells and Their Interaction Promotes Melanoma Progression. Biomolecules. 2022;12: pubmed publisher
Faust K, Freitag N, Barrientos G, Hartel C, Blois S. Galectin-Levels Are Elevated in Infants Born Preterm Due to Amniotic Infection and Rapidly Decline in the Neonatal Period. Front Immunol. 2020;11:599104 pubmed publisher
Freichel T, Heine V, Laaf D, Mackintosh E, Sarafova S, Elling L, et al. Sequence-Defined Heteromultivalent Precision Glycomacromolecules Bearing Sulfonated/Sulfated Nonglycosidic Moieties Preferentially Bind Galectin-3 and Delay Wound Healing of a Galectin-3 Positive Tumor Cell Line in an In Vitro Wound Scratch Assay. Macromol Biosci. 2020;20:e2000163 pubmed publisher
Freitag N, Tirado Gonzalez I, Barrientos G, Powell K, Boehm Sturm P, Koch S, et al. Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency. Cell Death Dis. 2020;11:560 pubmed publisher
Gallardo Vara E, Ruiz Llorente L, Casado Vela J, Ruiz Rodríguez M, Lopez Andres N, Pattnaik A, et al. Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners. Cells. 2019;8: pubmed publisher
Colomb F, Wang W, Simpson D, Zafar M, Beynon R, Rhodes J, et al. Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells. J Biol Chem. 2017;292:8381-8389 pubmed publisher
product information
master code :
BAF1154
SKU :
BAF1154
product name :
Human Galectin-3 Biotinylated Antibody
unit size :
50 ug
description :
The Human Galectin-3 Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to Galectin-3. This antibody reacts with human,n/a. The Human Galectin-3 Biotinylated Antibody has been validated for the following applications: Western Blot,ELISA Detection,Flow Cytometry,Immunoprecipitation,ELISA Detection (Matched Antibody Pair).
target :
Galectin-3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Biotin
host :
Goat
immunogen :
E. coli -derived recombinant human Galectin-3, Ala2-Ile250, Accession # Q6IBA7
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,N/A
specificity :
Detects human Galectin-3 in ELISAs and Western blots. In sandwich ELISAs, approximately 25% cross-reactivity with recombinant mouse Galectin-3 is observed and less than 0.2% cross-reactivity with recombinant human Galectin-1, -2, -4, -7, -8, and -10 is observed.
gene symbol :
LGALS3
accessionNumbers :
Q6IBA7
applications :
ELISA Detection,Flow Cytometry,Immunoprecipitation,Western Blot,ELISA Detection (Matched Antibody Pair)
USD :
549 USD
alt names :
AGE-R3, Carbohydrate-binding protein 35, CBP 35,35 kDa lectin, CBP35, Gal-3, GAL3, galactin-3, Galactose-specific lectin 3, Galactoside-binding protein, GALBPCBP35, galectin-3, Galectin3, GALIG, IgE-binding protein, L29, L31, L-31, Laminin-binding protein, Lectin L-29, lectin, galactoside-binding, soluble, 3, LGALS2, LGALS3, Mac-2, Mac-2 antigen, MAC2GAL3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.