product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human PD-1 Biotinylated Antibody
catalog :
BAF1086
quantity :
50 ug
price :
559 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
biotin
reactivity :
human, dogs, rhesus macaque
application :
western blot, ELISA, flow cytometry
more info or order :
citations: 4
Reference
Ohkuma R, Ieguchi K, Watanabe M, Takayanagi D, Goshima T, Onoue R, et al. Increased Plasma Soluble PD-1 Concentration Correlates with Disease Progression in Patients with Cancer Treated with Anti-PD-1 Antibodies. Biomedicines. 2021;9: pubmed publisher
Tagawa M, Kurashima C, Takagi S, Maekawa N, Konnai S, Shimbo G, et al. Evaluation of costimulatory molecules in dogs with B cell high grade lymphoma. PLoS ONE. 2018;13:e0201222 pubmed publisher
Watson D, Moysi E, Valentin A, Bergamaschi C, Devasundaram S, Fortis S, et al. Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes. PLoS Pathog. 2018;14:e1006902 pubmed publisher
Maekawa N, Konnai S, Okagawa T, Nishimori A, Ikebuchi R, Izumi Y, et al. Immunohistochemical Analysis of PD-L1 Expression in Canine Malignant Cancers and PD-1 Expression on Lymphocytes in Canine Oral Melanoma. PLoS ONE. 2016;11:e0157176 pubmed publisher
product information
brand :
R&D Systems
master code :
BAF1086
SKU :
BAF1086
product name :
Human PD-1 Biotinylated Antibody
unit size :
50 ug
seo description :
The Human PD-1 Biotinylated Antibody from R&D Systems is a goat polyclonal antibody to PD-1. This antibody reacts with canine,human,primate - macaca fascicularis (crab-eating monkey or cynomolgus macaque),primate - macaca mulatta (rhesus macaque). The Human PD-1 Biotinylated Antibody has been validated for the following applications: Confocal Microscopy,ELISA Development,Flow Cytometry,Western Blot,ELISA Detection (Matched Antibody Pair).
target :
PD-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Biotin
dilution :
Western Blot 0.1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human PD-1, Leu25-Gln167, Accession # Q8IX89
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Canine,Human,Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque),Primate - Macaca mulatta (Rhesus Macaque)
specificity :
Detects human PD-1 in ELISAs and Western blots. In sandwich ELISAs, less than 2% cross-reactivity with recombinant mouse PD-1 is observed and less than 0.2% cross-reactivity with recombinant human (rh) CD28, rhICOS, and rhCTLA-4 is observed.
gene symbol :
PDCD1
top caption :
Detection of PD-1 antibody in Human PBMCs treated with PHA antibody by Flow Cytometry.
accessionNumbers :
Q8IX89
applications :
Western Blot,ELISA Detection (Matched Antibody Pair),Confocal Microscopy,ELISA Development,Flow Cytometry
USD :
559 USD
alt names :
CD279, CD279 antigen, hPD-1, PD1, PD1hPD-l, PDCD1, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.