product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse IL-18/IL-1F4 Protein, CF
catalog :
B004-2
quantity :
200 ug
price :
2526 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Muñoz M, Eidenschenk C, Ota N, Wong K, Lohmann U, Kühl A, et al. Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection. Immunity. 2015;42:321-331 pubmed publisher
Antonopoulos C, Cumberbatch M, Mee J, Dearman R, Wei X, Liew F, et al. IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis. J Leukoc Biol. 2008;83:361-7 pubmed
Morinobu A, Gadina M, Strober W, Visconti R, Fornace A, Montagna C, et al. STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation. Proc Natl Acad Sci U S A. 2002;99:12281-6 pubmed
product information
master code :
B004-2
SKU :
B004-2
product name :
Recombinant Mouse IL-18/IL-1F4 Protein, CF
unit size :
200 ug
description :
The Recombinant Mouse IL-18/IL-1F4 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse IL-18/IL-1F4 Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-18/IL-1F4
category :
Proteins and Enzymes
buffer :
Lyophilized in PBS containing 1% sucrose.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.
species :
Mouse
theoretical molecular weight :
18 kDa
gene symbol :
Il18
details of functionality :
Induction of IFN-gamma by mouse IL-18 receptor transfected KG-1 cell [human myelomonocyte; ATCC CCL246] in response to the recombinant mouse IL-18 was measured using human IFN-gamma ELISA. The activity of lot 040 was as follows: IL-18 final concentration 5 ng/mL; IFN-gamma induction 2863 IU/mL and IL-18 final concentration 10 ng/mL; IFN-gamma induction 7312 IU/mL.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
applications :
Bioactivity
source long :
E. coli -derived mouse IL-18/IL-1F4 protein 36-192 aa
source short :
E. coli
extended description :
A New rm IL-18 is Now Available! Competitively priced; Enhanced stability; Lower endotoxin specification; Made in-house!
USD :
2526 USD
product details :
A New rm IL-18 is Now Available! Competitively priced; Enhanced stability; Lower endotoxin specification; Made in-house!
alt names :
Iboctadekin, IFN-gamma-inducing factor, IGIF, IGIFIL-1 gamma, IL18, IL-18MGC12320, IL-1F4, IL1F4iboctadekin, IL-1g, Interferon gamma-inducing factor, interleukin 18 (interferon-gamma-inducing factor), Interleukin-1 gamma, interleukin-18
storage :
Store the unopened product at -20 to -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.