Recombinant Mouse IL-18/IL-1F4 Protein | R&D Systems B002-5 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IL-18/IL-1F4 Protein

catalog :

B002-5

quantity :

25 ug

price :

588 USD

more info or order :

R&D Systems product webpage

citations: 35

Reference
Yu J, Zhu H, Taheri S, Mondy W, Bonilha L, Magwood G, et al. Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia. J Neurosci. 2019;39:9465-9476 pubmed publisher
Semper R, Vieth M, Gerhard M, Mejías Luque R. Helicobacter pylori Exploits the NLRC4 Inflammasome to Dampen Host Defenses. J Immunol. 2019;203:2183-2193 pubmed publisher
Lam V, Folkersen L, Aguilar O, Lanier L. KLF12 Regulates Mouse NK Cell Proliferation. J Immunol. 2019;203:981-989 pubmed publisher
Weizman O, Song E, Adams N, Hildreth A, Riggan L, Krishna C, et al. Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12. Nat Immunol. 2019;20:1004-1011 pubmed publisher
Mace T, Ware M, King S, Loftus S, Farren M, McMichael E, et al. Soy isoflavones and their metabolites modulate cytokine-induced natural killer cell function. Sci Rep. 2019;9:5068 pubmed publisher
Kumar P, Rajasekaran K, Nanbakhsh A, Gorski J, Thakar M, Malarkannan S. IL-27 promotes NK cell effector functions via Maf-Nrf2 pathway during influenza infection. Sci Rep. 2019;9:4984 pubmed publisher
Alhallaf R, Agha Z, Miller C, Robertson A, Sotillo J, Croese J, et al. The NLRP3 Inflammasome Suppresses Protective Immunity to Gastrointestinal Helminth Infection. Cell Rep. 2018;23:1085-1098 pubmed publisher
Nabekura T, Chen Z, Schroeder C, Park T, Vivier E, Lanier L, et al. Crk Adaptor Proteins Regulate NK Cell Expansion and Differentiation during Mouse Cytomegalovirus Infection. J Immunol. 2018;200:3420-3428 pubmed publisher
Wang Z, Liu Z, Wang L, Wang J, Chen L, Xie H, et al. Altered expression of IL-18 binding protein and IL-18 receptor in basophils and mast cells of asthma patients. Scand J Immunol. 2018;87:e12658 pubmed publisher
CASTILLO G, Nishimoto Ashfield A, Jones C, Kabirov K, Zakharov A, Lyubimov A. Protected graft copolymer-formulated fibroblast growth factors mitigate the lethality of partial body irradiation injury. PLoS ONE. 2017;12:e0171703 pubmed publisher
Ibiza S, García Cassani B, Ribeiro H, Carvalho T, Almeida L, Marques R, et al. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 2016;535:440-443 pubmed publisher
Seregin S, Chen G, Laouar Y. Dissecting CD8+ NKT Cell Responses to Listeria Infection Reveals a Component of Innate Resistance. J Immunol. 2015;195:1112-20 pubmed publisher
Nabekura T, Girard J, Lanier L. IL-33 receptor ST2 amplifies the expansion of NK cells and enhances host defense during mouse cytomegalovirus infection. J Immunol. 2015;194:5948-52 pubmed publisher
Souza Fonseca Guimaraes F, Young A, Mittal D, Martinet L, Bruedigam C, Takeda K, et al. NK cells require IL-28R for optimal in vivo activity. Proc Natl Acad Sci U S A. 2015;112:E2376-84 pubmed publisher
Gandhapudi S, Tan C, Marino J, Taylor A, Pack C, Gaikwad J, et al. IL-18 acts in synergy with IL-7 to promote ex vivo expansion of T lymphoid progenitor cells. J Immunol. 2015;194:3820-8 pubmed publisher
Chen P, Aguilar O, Rahim M, Allan D, Fine J, Kirkham C, et al. Genetic investigation of MHC-independent missing-self recognition by mouse NK cells using an in vivo bone marrow transplantation model. J Immunol. 2015;194:2909-18 pubmed publisher
Oficjalska K, Raverdeau M, Aviello G, Wade S, Hickey A, Sheehan K, et al. Protective role for caspase-11 during acute experimental murine colitis. J Immunol. 2015;194:1252-60 pubmed publisher
Marcais A, Cherfils Vicini J, Viant C, Degouve S, Viel S, Fenis A, et al. The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells. Nat Immunol. 2014;15:749-757 pubmed publisher
Celis Gutierrez J, Boyron M, Walzer T, Pandolfi P, Jonjic S, Olive D, et al. Dok1 and Dok2 proteins regulate natural killer cell development and function. EMBO J. 2014;33:1928-40 pubmed publisher
He W, Yang C, Xia L, Zhao M, Ge R, Huang H, et al. CD4(+) T cells from food allergy model are resistant to TCR-dependent apoptotic induction. Cytokine. 2014;68:32-9 pubmed publisher
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product information

master code :

B002-5

SKU :

B002-5

product name :

Recombinant Mouse IL-18/IL-1F4 Protein

unit size :

25 ug

description :

The Recombinant Mouse IL-18/IL-1F4 Protein from R&D Systems is derived from E. coli.

target :

IL-18/IL-1F4

category :

Proteins and Enzymes

buffer :

25 ╡g in PBS containing 0.1% BSA and 1% sucrose.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.

species :

Mouse

theoretical molecular weight :

18 kDa

gene symbol :

Il18

details of functionality :

Induction of IFN-gamma by Mouse IL-18 receptor transfected KG-1 cell [human myelomonocyte; ATCC CCL246] in response to the recombinant mouse IL-18 was measured using human IFN-gamma ELISA. The activity of lot 040 was as follows:IL-18 final concentration 5ng/mL; IFN-gamma induction 2863 IU/mL and IL-18 final concentration 10 ng/mL; IFN-gamma induction 7312 IU/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

source long :

E. coli -derived mouse IL-18/IL-1F4 protein 36-192 aa

source short :

E. coli

extended description :

A New rm IL-18 is Now Available! Competitively priced; Lower endotoxin specifications; Made in-house!

USD :

588 USD

product details :

A New rm IL-18 is Now Available! Competitively priced; Lower endotoxin specifications; Made in-house!

alt names :

Iboctadekin, IFN-gamma-inducing factor, IGIF, IGIFIL-1 gamma, IL18, IL-18MGC12320, IL-1F4, IL1F4iboctadekin, IL-1g, Interferon gamma-inducing factor, interleukin 18 (interferon-gamma-inducing factor), Interleukin-1 gamma, interleukin-18

storage :

Store the unopened product at -20 to -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

R&D Systems product webpage