product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-10 R alpha Fc Avi-tag Protein, CF
catalog :
AVI9044-050
quantity :
50 ug
price :
564 USD
more info or order :
citations: 1
Reference
Bennett N, Coventry B, Goreshnik I, Huang B, Allen A, Vafeados D, et al. Improving de novo protein binder design with deep learning. Nat Commun. 2023;14:2625 pubmed publisher
image
image 1 :
R&D Systems AVI9044-050 image 1
product information
master code :
AVI9044
SKU :
AVI9044-050
product name :
Recombinant Human IL-10 R alpha Fc Avi-tag Protein, CF
unit size :
50 ug
description :
The Recombinant Human IL-10 R alpha Fc Avi-tag Protein, CF from R&D Systems is derived from CHO. The Recombinant Human IL-10 R alpha Fc Avi-tag Protein, CF has been validated for the following applications: Bioactivity, Gel Filtration Chromatography.
target :
IL-10 R alpha
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Biotin
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
74-85 kDa, under reducing conditions
theoretical molecular weight :
53 kDa
details of functionality :
The biotin to protein ratio is greater than 0.7 as determined by the HABA assay. Measured by its binding ability in a functional ELISA. When Recombinant Human IL-10 (Catalog # 217-IL/CF or Catalog # 217-ILB/CF ) is coated at 2 ╡g/mL (100 ╡L/well), Biotinylated Recombinant Human IL-10 R alpha Fc Chimera Avi-tag binds with an ED50 of 20-100 ng/mL Measured by its ability to inhibit IL-10-dependent proliferation of MC/9-2 mouse mast cells. Thompson-Snipes, L.á et al . (1991) J. Exp. Med. 173 :507. The ED50 for this effect is 6-48 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q13651.2
applications :
Bioactivity, Gel Filtration Chromatography
source long :
Chinese Hamster Ovary cell line, CHO-derived human IL-10 R alpha protein Human IL-10 R alpha (His22-Asn235) Accession # Q13651.2 IEGRMD Human IgG1 (Pro100-Lys330) Avi-tag N-terminus C-terminus
source short :
CHO
extended description :
Biotinylated
USD :
564 USD
product details :
Biotinylated
alt names :
CD210 antigen, CDw210a, HIL-10R, IBD28, IL-10 receptor subunit alpha, IL10R alpha, IL-10R subunit 1, IL-10R1, IL10RA, IL-10RA, IL10RIL-10R subunit alpha, interleukin 10 receptor, alpha, interleukin-10 receptor alpha chain, Interleukin-10 receptor subunit 1, interleukin-10 receptor subunit alpha
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.