Recombinant Human HSP70/HSPA1A Protein, CF | R&D Systems AP-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human HSP70/HSPA1A Protein, CF

catalog :

AP-100

quantity :

50 ug (also 100 ug)

price :

309 USD

citations: 2

Reference
Borges T, Murakami N, Machado F, Murshid A, Lang B, Lopes R, et al. March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity. Nat Commun. 2018;9:3482 pubmed publisher
Ohara K, Shimizu K, Matsuura S, Ogiso B, Omagari D, Asano M, et al. Toll-like receptor 4 signaling in trigeminal ganglion neurons contributes tongue-referred pain associated with tooth pulp inflammation. J Neuroinflammation. 2013;10:139 pubmed publisher

product information

brand :

R&D Systems, powered by Boston Biochem

master code :

AP-100

SKU :

AP-100-050

product name :

Recombinant Human HSP70/HSPA1A Protein, CF

description :

The Recombinant Human HSP70/HSPA1A Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human HSP70/HSPA1A Protein, CF has been validated for the following applications: Enzyme Activity.

target :

HSP70 / HSPA1A

category :

Proteins and Enzymes

unit size :

50 ug (also 100 ug)

buffer :

X mg/ml (X µM) in 50 mM HEPES pH 8, 100 mM NaCl, 5 mM DTT

conjugate :

Unconjugated

main entrez gene id :

3303

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain.

species :

Human

theoretical molecular weight :

70 kDa

gene symbol :

HSPA1A

details of functionality :

HSP70/HSPA1A is a molecular chaperone that assists in the folding of nascent polypeptides and the refolding of denatured proteins, but can also promote their degradation in conjunction with specific E3 ligases, such as CHIP, if either of these processes proceeds inefficiently. Reaction conditions will need to be optimized for each specific application. We recommend an initial HSP70/HSPA1A concentration of 2-3 µM for in vitro use. IMPORTANT: HSP40/DNAJB1 (Catalog # AP-110), or another suitable co-chaperone, is required for HSP70/HSPA1A activity and should be used at a concentration that is equimolar to HSP70/HSPA1A.

catalog number base :

AP-100

accessionNumbers :

AAD21816

applications :

Enzyme Activity

source :

The Recombinant Human HSP70 / HSPA1A Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human HSP70 / HSPA1A Protein, CF has been validated for the following applications: Enzyme Activity.

USD :

309 USD

alt names :

dnaK-type molecular chaperone HSP70-1, FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, Heat shock 70 kDa protein 1/2, heat shock 70 kDa protein 1A/1B, heat shock 70kD protein 1A, heat shock 70kDa protein 1A, heat shock-induced protein, HSP70.1/HSP70.2, HSP70-1, HSP70-1/HSP70-2, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1A, HSPA1B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.