Recombinant Human HSP70/HSPA1A Protein, CF | R&D Systems AP-100-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human HSP70/HSPA1A Protein, CF

catalog :

AP-100-050

quantity :

50 ug (also 100 ug)

price :

402 USD

citations: 5

Reference
Zhou L, Fang L, Tamm M, Stolz D, Roth M. Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual-Specificity Phosphatase 1 via Toll-like Receptor 4 and Attenuates Inflammation in Airway Epithelial Cells. Int J Mol Sci. 2023;24: pubmed publisher
Kanno K, Shimizu K, Shinoda M, Hayashi M, Takeichi O, Iwata K. Role of macrophage-mediated Toll-like receptor 4-interleukin-1R signaling in ectopic tongue pain associated with tooth pulp inflammation. J Neuroinflammation. 2020;17:312 pubmed publisher
Borges T, Murakami N, Machado F, Murshid A, Lang B, Lopes R, et al. March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity. Nat Commun. 2018;9:3482 pubmed publisher
Ali Y, Allen H, Yu L, Li Kroeger D, Bakhshizadehmahmoudi D, Hatcher A, et al. NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. PLoS Biol. 2016;14:e1002472 pubmed publisher
Ohara K, Shimizu K, Matsuura S, Ogiso B, Omagari D, Asano M, et al. Toll-like receptor 4 signaling in trigeminal ganglion neurons contributes tongue-referred pain associated with tooth pulp inflammation. J Neuroinflammation. 2013;10:139 pubmed publisher

product information

master code :

AP-100

SKU :

AP-100-050

product name :

Recombinant Human HSP70/HSPA1A Protein, CF

unit size :

50 ug (also 100 ug)

description :

The Recombinant Human HSP70/HSPA1A Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human HSP70/HSPA1A Protein, CF has been validated for the following applications: Enzyme Activity.

target :

HSP70/HSPA1A

category :

Proteins and Enzymes

buffer :

Supplied as a solution in HEPES, NaCl, DTT.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.

species :

Human

theoretical molecular weight :

70 kDa

gene symbol :

HSPA1A

details of functionality :

Reaction conditions will need to be optimized for each specific application. We recommend an initial HSP70/HSPA1A concentration of 2-3 ╡M for in vitro use. IMPORTANT: HSP40/DNAJB1 (Catalog # AP-110), or another suitable co-chaperone, is required for HSP70/HSPA1A activity and should be used at a concentration that is equimolar to HSP70/HSPA1A.

accessionNumbers :

AAD21816.1

applications :

Enzyme Activity

source long :

E. coli -derived human HSP70/HSPA1A protein Met1 - Asp641

source short :

E. coli

USD :

402 USD

alt names :

dnaK-type molecular chaperone HSP70-1, FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, Heat shock 70 kDa protein 1/2, heat shock 70 kDa protein 1A/1B, heat shock 70kD protein 1A, heat shock 70kDa protein 1A, heat shock-induced protein, HSP70.1/HSP70.2, HSP70-1, HSP70-1/HSP70-2, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1A, HSPA1B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.