product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human HSP70/HSPA1A Protein, CF
catalog :
AP-100-050
quantity :
50 ug (also 100 ug)
price :
402 USD
more info or order :
R&D Systems product webpage
citations: 5
Reference
Zhou L, Fang L, Tamm M, Stolz D, Roth M. Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual-Specificity Phosphatase 1 via Toll-like Receptor 4 and Attenuates Inflammation in Airway Epithelial Cells. Int J Mol Sci. 2023;24: pubmed publisher
Kanno K, Shimizu K, Shinoda M, Hayashi M, Takeichi O, Iwata K. Role of macrophage-mediated Toll-like receptor 4-interleukin-1R signaling in ectopic tongue pain associated with tooth pulp inflammation. J Neuroinflammation. 2020;17:312 pubmed publisher
Borges T, Murakami N, Machado F, Murshid A, Lang B, Lopes R, et al. March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity. Nat Commun. 2018;9:3482 pubmed publisher
Ali Y, Allen H, Yu L, Li Kroeger D, Bakhshizadehmahmoudi D, Hatcher A, et al. NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. PLoS Biol. 2016;14:e1002472 pubmed publisher
Ohara K, Shimizu K, Matsuura S, Ogiso B, Omagari D, Asano M, et al. Toll-like receptor 4 signaling in trigeminal ganglion neurons contributes tongue-referred pain associated with tooth pulp inflammation. J Neuroinflammation. 2013;10:139 pubmed publisher
product information
master code :
AP-100
SKU :
AP-100-050
product name :
Recombinant Human HSP70/HSPA1A Protein, CF
unit size :
50 ug (also 100 ug)
description :
The Recombinant Human HSP70/HSPA1A Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human HSP70/HSPA1A Protein, CF has been validated for the following applications: Enzyme Activity.
target :
HSP70/HSPA1A
category :
Proteins and Enzymes
buffer :
Supplied as a solution in HEPES, NaCl, DTT.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.
species :
Human
theoretical molecular weight :
70 kDa
gene symbol :
HSPA1A
details of functionality :
Reaction conditions will need to be optimized for each specific application. We recommend an initial HSP70/HSPA1A concentration of 2-3 ╡M for in vitro use. IMPORTANT: HSP40/DNAJB1 (Catalog # AP-110), or another suitable co-chaperone, is required for HSP70/HSPA1A activity and should be used at a concentration that is equimolar to HSP70/HSPA1A.
accessionNumbers :
AAD21816.1
applications :
Enzyme Activity
source long :
E. coli -derived human HSP70/HSPA1A protein Met1 - Asp641
source short :
E. coli
USD :
402 USD
alt names :
dnaK-type molecular chaperone HSP70-1, FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, Heat shock 70 kDa protein 1/2, heat shock 70 kDa protein 1A/1B, heat shock 70kD protein 1A, heat shock 70kDa protein 1A, heat shock-induced protein, HSP70.1/HSP70.2, HSP70-1, HSP70-1/HSP70-2, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1A, HSPA1B
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.