Recombinant Human IGF-I/IGF-1, Animal-Free Protein | R&D Systems AFL291-01M product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IGF-I/IGF-1, Animal-Free Protein

catalog :

AFL291-01M

quantity :

1 mg (also 200 ug)

price :

822 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Sharma R, George A, Nimmagadda M, Ortolan D, Karla B, Qureshy Z, et al. Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model. Nat Commun. 2021;12:7293 pubmed publisher
Zheng Q, Gan H, Yang F, Yao Y, Hao F, Hong L, et al. Cytoplasmic m1A reader YTHDF3 inhibits trophoblast invasion by downregulation of m1A-methylated IGF1R. Cell Discov. 2020;6:12 pubmed publisher

product information

master code :

AFL291

SKU :

AFL291-01M

product name :

Recombinant Human IGF-I/IGF-1, Animal-Free Protein

unit size :

1 mg (also 200 ug)

description :

The Recombinant Human IGF-I/IGF-1, Animal-Free Protein from R&D Systems is derived from E. coli. The Recombinant Human IGF-I/IGF-1, Animal-Free Protein has been validated for the following applications: Bioactivity.

target :

IGF-I/IGF-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

7.6 kDa

gene symbol :

IGF1

details of functionality :

Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is 0.3-1.5 ng/mL. The specific activity of recombinant human IGF-I/IGF-1 is 1000 IU/mg, which is calibrated against the human IGF-I/IGF-1 WHO International Standard (NIBSC code: 91/554).

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P05019.1

applications :

Bioactivity

source long :

E. coli -derived human IGF-I/IGF-1 protein Gly49-Ala118 Produced using non-animal reagents in an animal-free laboratory.

source short :

E. coli

extended description :

Intended for preclinical researchers who may transition to GMP IGF-I/IGF-1 for their clinical work

USD :

822 USD

product details :

Intended for preclinical researchers who may transition to GMP IGF-I/IGF-1 for their clinical work

alt names :

IBP1, IGF1, IGF-1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, Somatomedin A, Somatomedin C, Somatomedin-C

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage