Recombinant Human IL-1 beta/IL-1F2, Animal-Free Protein | R&D Systems AFL201 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-1 beta/IL-1F2, Animal-Free Protein

catalog :

AFL201

quantity :

1 mg (also 25 ug)

price :

6415 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Younes S, Freeman M, Mudd J, Shive C, Reynaldi A, Panigrahi S, et al. IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection. J Clin Invest. 2016;126:2745-56 pubmed publisher

product information

master code :

AFL201

SKU :

AFL201

product name :

Recombinant Human IL-1 beta/IL-1F2, Animal-Free Protein

unit size :

1 mg (also 25 ug)

description :

The Recombinant Human IL-1 beta/IL-1F2, Animal-Free Protein from R&D Systems is derived from E. coli. The Recombinant Human IL-1 beta/IL-1F2, Animal-Free Protein has been validated for the following applications: Bioactivity.

target :

IL-1 beta/IL-1F2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

theoretical molecular weight :

17 kDa

gene symbol :

IL1B

details of functionality :

Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons, J.A. etáal . (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. etáal . (eds): IRL Press. 272. The ED50 for this effect is 12 pg/mL. The specific activity of Recombinant Human IL-1▀ is 5.0 x 107 IU/mg, which is calibrated against recombinant human IL-1▀ WHO International Standard (NIBSC code: 86/680).

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_000567.1

applications :

Bioactivity

source long :

E. coli -derived human IL-1 beta/IL-1F2 protein Ala117-Ser269 Produced using non-animal reagents in an animal-free laboratory.

source short :

E. coli

extended description :

Intended for preclinical researchers who may transition to GMP IL-1beta for their clinical work

USD :

6415 USD

product details :

Intended for preclinical researchers who may transition to GMP IL-1beta for their clinical work

alt names :

catabolin, IL-1, IL1 beta, IL-1 beta, IL-1b, IL1B, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin 1, beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 12 months, 2 to 8 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage